ChemicalBook > CAS DataBase List > ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid

Product Name
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
CAS No.
1132709-14-8
Chemical Name
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
Synonyms
2S)-Bortezomib;(1S,2S)-BortezoMib;Bortezomib (1S, 2S);Bortizomib SS-isomer;Bortezomib S,S Isomer;Bortezomib Impurity PS619;Bortezomib USP Impurity G;Bortezomib (1S,2S) isomer;(1S,2S)-Bortezomib Impurity;Bortezomib Diastereomer (S,S)
CBNumber
CB12661930
Molecular Formula
C19H25BN4O4
Formula Weight
384.24
MOL File
1132709-14-8.mol
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((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Property

Density 
1.214±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (130.13 mM; Need ultrasonic)
form 
Solid
pka
9.66±0.43(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
InChIKey
GXJABQQUPOEUTA-DOTOQJQBSA-N
SMILES
B([C@H](NC(=O)[C@@H](NC(C1=NC=CN=C1)=O)CC1=CC=CC=C1)CC(C)C)(O)O
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B675715
Product name
(1S,2S)-Bortezomib
Packaging
1mg
Price
$205
Updated
2021/12/16
Alichem
Product number
1132709148
Product name
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid
Packaging
100mg
Price
$956.8
Updated
2021/12/16
Alichem
Product number
1132709148
Product name
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid
Packaging
250mg
Price
$1501.44
Updated
2021/12/16
Alichem
Product number
1132709148
Product name
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid
Packaging
1g
Price
$3900.8
Updated
2021/12/16
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((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Chemical Properties,Usage,Production

Uses

(1S,2S)-Bortezomib is an isomer of Bortezomib (B675700), proteasome inhibitor. (1S,2S)-Bortezomib has been seen to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer’s or hypertension.

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Suppliers

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1132709-14-8, ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acidRelated Search:

Bortezomib Impurity 1 (R,S-Isomer) BortezoMib IMpurity 2 (RR-IsoMer) 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Bortezomib ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- ANTI-ESTROGEN RECEPTOR FARNESENE ESTETROL 2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris- BORTEZOMIB-PINANEDIOL Bortezomib Impurity 2 (Mixture of (1S,2R)-Isomer and (1R,2R)-Isomer)

  • ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
  • Boronic acid, B-[(1S)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
  • (1S,2S)-BortezoMib
  • (1S,2S)-Bortezomib Impurity
  • [(1S)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2[(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid
  • Bortezomib Impurity PS619
  • N-(2-Pyrazinecarbonyl)-L-phenylalanine-D-leucine boronic anhydride
  • Bortezomib (1S,2S) Isomer Impurity
  • Bortezomib USP Impurity G
  • [(1S)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
  • Bortezomib impurity 3/(1S,2S)-Bortezomib
  • Bortezomib (1S, 2S)
  • Bortezomib (1S,2S) isomer
  • (1s) - 3-methyl-1 - [[(2S) - 1-oxo-3-phenyl-2 - [(pyrazinoformyl) - amino] propyl] amino] butyl] boric acid
  • Bortizomib SS-isomer
  • Bortezomib Related Compound G (Bortezomib S,S-Isomer Impurity)
  • Bortezomib Diastereomer (S,S)
  • ((R)-3-hydroxy-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid
  • 2S)-Bortezomib
  • ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)prop
  • Bortezomib S,S Isomer
  • 2-hydroxy-36-(methylthio)butanamide
  • (1S,2S)-Bortezomib, 10 mM in DMSO
  • 1132709-14-8
  • Chiral Reagents, Boron Derivatives, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals