Effect Mechanism of action
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scutellarin Methylester

Effect Mechanism of action
Product Name
scutellarin Methylester
CAS No.
119262-68-9
Chemical Name
scutellarin Methylester
Synonyms
Scutellarin Methlester;scutellarin Methylester;Breviscapine methyl ester;β-D-Glucopyranosiduronic acid, 5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl, methyl ester;5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl beta-D-glucopyranosiduronic acid methyl ester;(2S,3S,4S,5R,6S)-Methyl 6-((5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate
CBNumber
CB12672945
Molecular Formula
C22H20O12
Formula Weight
476.39
MOL File
119262-68-9.mol
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scutellarin Methylester Property

Boiling point:
804.0±65.0 °C(Predicted)
Density 
1.697±0.06 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
pka
5.92±0.40(Predicted)
color 
Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
300947
Product name
Scutellarin methyl ester
Packaging
10mg
Price
$446
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS74250
Product name
Scutellarin methylester
Packaging
25mg
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS74250
Product name
Scutellarin methylester
Packaging
50mg
Price
$136
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS74250
Product name
Scutellarin methylester
Packaging
100mg
Price
$231
Updated
2021/12/16
ChemScene
Product number
CS-0027792
Product name
Scutellarinmethylester
Packaging
5mg
Price
$269
Updated
2021/12/16
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scutellarin Methylester Chemical Properties,Usage,Production

Effect

The improvement effect of scutellarin methylester on ischemic brain tissue showed that scutellarin methylester can effectively improve the local cerebral blood flow of ischemia-reperfusion in rats, and significantly reduce the degree of ischemic damage to brain tissue. The mechanism may be In order to inhibit cerebral vasospasm caused by protein kinase activation, increase local cerebral blood flow, improve cerebral microcirculation, and reduce inflammatory cell adhesion and infiltration, thereby reducing brain damage.

Mechanism of action

Scutellarin methylester mainly inhibits the formation of thrombus in vitro through three steps, reducing platelet count, inhibiting platelet aggregation function, inhibiting coagulation function in vivo, and promoting fibrinolytic activity, of which the latter two have stronger effects.    

Definition

ChEBI: Scutellarin methyl ester is a glucosiduronic acid and a member of flavonoids.

scutellarin Methylester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from scutellarin Methylester manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Scutellarin methylester 119262-68-9
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-11
Career Henan Chemical Co
Product
Scutellarin methyl ester 119262-68-9
Price
US $9.80/KG
Min. Order
1g
Purity
>98%
Supply Ability
20 tons
Release date
2020-02-10

119262-68-9, scutellarin MethylesterRelated Search:


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  • (2S,3S,4S,5R,6S)-Methyl 6-((5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate
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