Methyl 4-amino-3-methylbenzoate
- Product Name
- Methyl 4-amino-3-methylbenzoate
- CAS No.
- 18595-14-7
- Chemical Name
- Methyl 4-amino-3-methylbenzoate
- Synonyms
- METHYL 3-METHYL-4-AMINOBENZOATE;AKOS BB-3094;benzenecarboxyL;4-Amino-3-methyl;BUTTPARK 37\12-51;Methyl 4-amino-3-met;Methyl 4-Amino-m-toluate;methyl-4-amino-3-methylbenzate;Methyl 4-Amion-3-Methylbenzoate;METHYL 4-AMINO-3-METHYLBENZOATE
- CBNumber
- CB1267532
- Molecular Formula
- C9H11NO2
- Formula Weight
- 165.19
- MOL File
- 18595-14-7.mol
Methyl 4-amino-3-methylbenzoate Property
- Melting point:
- 116 °C
- Boiling point:
- 314.8±22.0 °C(Predicted)
- Density
- 1.132±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO, Methanol
- form
- Solid
- pka
- 2.32±0.10(Predicted)
- color
- Light Beige
- CAS DataBase Reference
- 18595-14-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-37/38-36-22
- Safety Statements
- 26-37/39
- HazardClass
- IRRITANT
- HS Code
- 2922498590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M2152
- Product name
- Methyl 4-Amino-3-methylbenzoate
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $42
- Updated
- 2025/07/31
- Product number
- M2152
- Product name
- Methyl 4-Amino-3-methylbenzoate
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $167
- Updated
- 2025/07/31
- Product number
- M266140
- Product name
- Methyl 4-Amino-3-methylbenzoate
- Packaging
- 100g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 017420
- Product name
- Methyl 4-Amino-3-methylbenzoate
- Purity
- 99%
- Packaging
- 1g
- Price
- $9
- Updated
- 2021/12/16
- Product number
- 017420
- Product name
- Methyl 4-Amino-3-methylbenzoate
- Purity
- 99%
- Packaging
- 5g
- Price
- $10
- Updated
- 2021/12/16
Methyl 4-amino-3-methylbenzoate Chemical Properties,Usage,Production
Chemical Properties
White to light yellow crystal powder
Uses
Methyl 4-Amino-3-methylbenzoate is used in the synthesis of neuroprotective hydrazides used in the treatment of Alzheimer’s. It is also used in the research and development of diphenylamine-based retinoids.
Synthesis
24078-21-5
18595-14-7
The general procedure for the synthesis of methyl 4-amino-3-methylbenzoate from methyl 3-methyl-4-nitrobenzoate was as follows: methyl 3-methyl-4-nitrobenzoate (50 g, 256.2 mmol) was dissolved in methanol (1.5 L), and palladium carbon catalyst (2.5 g) was added. Hydrogen (H2) was passed into the reaction mixture at room temperature and the reaction was continuously stirred overnight. Upon completion of the reaction, the solid catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford the light yellow solid product methyl 4-amino-3-methylbenzoate (38 g, 90% yield). The product was analyzed by LCMS (electrospray ionization, positive ion mode) with a mass-to-charge ratio (m/z) of 166.1, corresponding to the [M + H]+ ion peak.
References
[1] Tetrahedron, 2018, vol. 74, # 47, p. 6795 - 6803
[2] Journal of Heterocyclic Chemistry, 2003, vol. 40, # 6, p. 1107 - 1112
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 14, p. 4582 - 4589
[4] Patent: WO2014/66795, 2014, A1. Location in patent: Paragraph 0175
[5] Zeitschrift fur Anorganische und Allgemeine Chemie, 2014, vol. 640, # 1, p. 159 - 167
Methyl 4-amino-3-methylbenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 4-amino-3-methylbenzoate manufacturers
- Product
- Methyl 4-amino-3-methylbenzoate 18595-14-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-13
- Product
- Methyl 4-amino-3-methylbenzoate 18595-14-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-09
- Product
- Methyl 4-amino-3-methylbenzoate 18595-14-7
- Price
- US $41.89/Kg/Drum
- Min. Order
- 25Kg/Drum
- Purity
- 99.00%HPLC
- Supply Ability
- 30tons/month
- Release date
- 2021-09-16