ChemicalBook > CAS DataBase List > 5-chloro-2,3-diphenylpyrazine

5-chloro-2,3-diphenylpyrazine

Product Name
5-chloro-2,3-diphenylpyrazine
CAS No.
41270-66-0
Chemical Name
5-chloro-2,3-diphenylpyrazine
Synonyms
Selexipag Impurity 31;2-Chloro-5,6-diphenylpyrazine;Pyrazine, 5-chloro-2,3-diphenyl-;5-chlChemicalbookoro-2,3-diphenylpyrazine;chloro-2,3-diphenylpyrazine (Selexipag Intermediate)
CBNumber
CB12676877
Molecular Formula
C16H11ClN2
Formula Weight
266.72
MOL File
41270-66-0.mol
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5-chloro-2,3-diphenylpyrazine Property

Melting point:
126-128℃ (methanol )
Boiling point:
145°C/0.001mmHg(lit.)
Density 
1?+-.0.06 g/cm3(Predicted)
pka
-2.16±0.10(Predicted)
form 
powder to crystal
color 
White to Orange to Green
InChI
InChI=1S/C16H11ClN2/c17-14-11-18-15(12-7-3-1-4-8-12)16(19-14)13-9-5-2-6-10-13/h1-11H
InChIKey
VUGNCPVAXWZTOL-UHFFFAOYSA-N
SMILES
C1(C2=CC=CC=C2)=NC=C(Cl)N=C1C1=CC=CC=C1
CAS DataBase Reference
41270-66-0
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Safety

HS Code 
2933.99.5300
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
C3205
Product name
5-Chloro-2,3-diphenylpyrazine
Purity
>98.0%(GC)
Packaging
1g
Price
$88
Updated
2024/03/01
TCI Chemical
Product number
C3205
Product name
5-Chloro-2,3-diphenylpyrazine
Purity
>98.0%(GC)
Packaging
5g
Price
$439
Updated
2024/03/01
TRC
Product number
C365848
Product name
2-Chloro-5,6-diphenylpyrazine
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
C365848
Product name
2-Chloro-5,6-diphenylpyrazine
Packaging
1g
Price
$105
Updated
2021/12/16
AK Scientific
Product number
5680AB
Product name
5-Chloro-2,3-diphenylpyrazine
Packaging
5g
Price
$273
Updated
2021/12/16
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5-chloro-2,3-diphenylpyrazine Chemical Properties,Usage,Production

Uses

2-Chloro-5,6-diphenylpyrazine is a diphenylpyrazine derivative used in a study to determine a novel class of prostacyclin receptor agonists.

Synthesis

50 gm of 2-hydroxy-5,6-diphenylpyrazine obtained was treated with 250 ml of POCI3 and then heated the reaction mixture at 100-110 °C with stirring for 5-6 hrs. The reaction mixture was cooled to room temperature and poured in 1000 ml of ice water at 0-5 °C and maintained with stirring for 60 minutes. The solid obtained was filtered, washed with water and dried to obtain 41.3 gm of 5-chloro-2,3-diphenylpyrazine. Yield: 77.00 percent.

5-chloro-2,3-diphenylpyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-chloro-2,3-diphenylpyrazine manufacturers

Henan Fengda Chemical Co., Ltd
Product
5-chloro-2,3-diphenylpyrazine 41270-66-0
Price
US $8.00-2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-24
Shaanxi Haibo Biotechnology Co., Ltd
Product
5-chloro-2,3-diphenylpyrazine 41270-66-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-31
Hangzhou ICH Biofarm Co., Ltd
Product
5-chloro-2,3-diphenylpyrazine 41270-66-0
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
99.0%min
Supply Ability
2000kg
Release date
2023-06-09

41270-66-0, 5-chloro-2,3-diphenylpyrazineRelated Search:

Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]- 2-Pyrazinamine, N-(1-methylethyl)-5,6-diphenyl- 5,6-DIPHENYLPYRAZIN-2-OL N-(methylsulfonyl)glycine 2,3-Dichloro-5,6-diphenylpyrazine 1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)oxy]- 2,3-DIPHENYLPYRAZINE Bromoacetic acid 2-T-BUTYL GLYCOLATE 4-(Isopropylamino)butanol Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]-, 1,1-dimethylethyl ester ( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester ) SELEXIPAG interMediate [4-[(5,6-DIPHENYLPYRAZINYL)(1-METHYLETHYL)AMINO]BUTOXY]-ACETIC ACID Acetamide, 2-[4-[(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)- Acetamide, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-

  • 2-Chloro-5,6-diphenylpyrazine
  • Pyrazine, 5-chloro-2,3-diphenyl-
  • Selexipag Impurity 31
  • chloro-2,3-diphenylpyrazine (Selexipag Intermediate)
  • 5-chlChemicalbookoro-2,3-diphenylpyrazine
  • 41270-66-0
  • Selexipag intermediate