5-chloro-2,3-diphenylpyrazine

Product Name: 5-chloro-2,3-diphenylpyrazine
CAS No.: 41270-66-0
Chemical Name: 5-chloro-2,3-diphenylpyrazine
Synonyms: Selexipag Impurity 31;2-Chloro-5,6-diphenylpyrazine;Pyrazine, 5-chloro-2,3-diphenyl-;5-chlChemicalbookoro-2,3-diphenylpyrazine;chloro-2,3-diphenylpyrazine (Selexipag Intermediate)
CBNumber: CB12676877
Molecular Formula: C16H11ClN2
Formula Weight: 266.72
MOL File: 41270-66-0.mol

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5-chloro-2,3-diphenylpyrazine Property

Melting point:: 126-128℃ (methanol )
Boiling point:: 145°C/0.001mmHg(lit.)
Density: 1?+-.0.06 g/cm3(Predicted)
pka: -2.16±0.10(Predicted)
form: powder to crystal
color: White to Orange to Green
InChI: InChI=1S/C16H11ClN2/c17-14-11-18-15(12-7-3-1-4-8-12)16(19-14)13-9-5-2-6-10-13/h1-11H
InChIKey: VUGNCPVAXWZTOL-UHFFFAOYSA-N
SMILES: C1(C2=CC=CC=C2)=NC=C(Cl)N=C1C1=CC=CC=C1
CAS DataBase Reference: 41270-66-0

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Safety

HS Code: 2933.99.5300

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: C3205
Product name: 5-Chloro-2,3-diphenylpyrazine
Purity: >98.0%(GC)
Packaging: 1g
Price: $88
Updated: 2024/03/01

TCI Chemical

Product number: C3205
Product name: 5-Chloro-2,3-diphenylpyrazine
Purity: >98.0%(GC)
Packaging: 5g
Price: $439
Updated: 2024/03/01

TRC

Product number: C365848
Product name: 2-Chloro-5,6-diphenylpyrazine
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: C365848
Product name: 2-Chloro-5,6-diphenylpyrazine
Packaging: 1g
Price: $105
Updated: 2021/12/16

AK Scientific

Product number: 5680AB
Product name: 5-Chloro-2,3-diphenylpyrazine
Packaging: 5g
Price: $273
Updated: 2021/12/16

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5-chloro-2,3-diphenylpyrazine Chemical Properties,Usage,Production

Uses

2-Chloro-5,6-diphenylpyrazine is a diphenylpyrazine derivative used in a study to determine a novel class of prostacyclin receptor agonists.

Synthesis

50 gm of 2-hydroxy-5,6-diphenylpyrazine obtained was treated with 250 ml of POCI3 and then heated the reaction mixture at 100-110 °C with stirring for 5-6 hrs. The reaction mixture was cooled to room temperature and poured in 1000 ml of ice water at 0-5 °C and maintained with stirring for 60 minutes. The solid obtained was filtered, washed with water and dried to obtain 41.3 gm of 5-chloro-2,3-diphenylpyrazine. Yield: 77.00 percent.

5-chloro-2,3-diphenylpyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-chloro-2,3-diphenylpyrazine Suppliers

Americas 1 CHINA 172 Europe 1 India 8 Japan 1 United States 6 Global 189

Aladdin Scientific

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Synthonix Inc

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Combi-Blocks Inc.

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TCI America

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Matrix Scientific

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International Laboratory Limited

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View Lastest Price from 5-chloro-2,3-diphenylpyrazine manufacturers

Henan Fengda Chemical Co., Ltd

Product: 5-chloro-2,3-diphenylpyrazine 41270-66-0
Price: US $8.00-2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-24

Shaanxi Haibo Biotechnology Co., Ltd

Product: 5-chloro-2,3-diphenylpyrazine 41270-66-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-31

Hangzhou ICH Biofarm Co., Ltd

Product: 5-chloro-2,3-diphenylpyrazine 41270-66-0
Price: US $0.00-0.00/kg
Min. Order: 0.1kg
Purity: 99.0%min
Supply Ability: 2000kg
Release date: 2023-06-09

41270-66-0, 5-chloro-2,3-diphenylpyrazineRelated Search:

Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]- 2-Pyrazinamine, N-(1-methylethyl)-5,6-diphenyl- 5,6-DIPHENYLPYRAZIN-2-OL N-(methylsulfonyl)glycine 2,3-Dichloro-5,6-diphenylpyrazine 1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)oxy]- 2,3-DIPHENYLPYRAZINE Bromoacetic acid 2-T-BUTYL GLYCOLATE 4-(Isopropylamino)butanol Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]-, 1,1-dimethylethyl ester ( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester ) SELEXIPAG interMediate [4-[(5,6-DIPHENYLPYRAZINYL)(1-METHYLETHYL)AMINO]BUTOXY]-ACETIC ACID Acetamide, 2-[4-[(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)- Acetamide, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-

2-Chloro-5,6-diphenylpyrazine

Pyrazine, 5-chloro-2,3-diphenyl-

Selexipag Impurity 31

chloro-2,3-diphenylpyrazine (Selexipag Intermediate)

5-chlChemicalbookoro-2,3-diphenylpyrazine

41270-66-0

Selexipag intermediate