Uridine 5'-monophosphate

Product Name: Uridine 5'-monophosphate
CAS No.: 58-97-9
Chemical Name: Uridine 5'-monophosphate
Synonyms: URIDYLIC ACID;((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl dihydrogen phosphate;5’-ump;UMP.H2;uridinemonophosphate;Uridine Monophospahte;Uridine 5’-monophosphte;UMP-H;U 5'-P;98-100%
CBNumber: CB1271654
Molecular Formula: C9H13N2O9P
Formula Weight: 324.18
MOL File: 58-97-9.mol

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Uridine 5'-monophosphate Property

Melting point:: 202°C (rough estimate)
Density: 1.865±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: H2O: soluble50mg/mL, clear, colorless
form: solid
pka: pK1:6.63 (25°C)
color: White to Off-White
biological source: natural (organic)
Water Solubility: H2O: soluble 50mg/mL, clear, colorless
InChI: InChI=1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKey: DJJCXFVJDGTHFX-XVFCMESISA-N
SMILES: P(OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](O)[C@@H]1O)(O)(O)=O
CAS DataBase Reference: 58-97-9
EPA Substance Registry System: 5'-Uridylic acid (58-97-9)

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Safety

Safety Statements: 24/25
WGK Germany: 3
RTECS: YU8088000
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: U1752
Product name: Uridine 5′-monophosphate
Purity: ≥98%
Packaging: 1g
Price: $215.99
Updated: 2025/07/31

TCI Chemical

Product number: U0078
Product name: Uridine 5'-Monophosphate
Packaging: 5G
Price: $115
Updated: 2025/07/31

TCI Chemical

Product number: U0078
Product name: Uridine 5'-Monophosphate
Packaging: 25G
Price: $345
Updated: 2025/07/31

TRC

Product number: U830020
Product name: Uridine 5′-monophosphate
Packaging: 2.5g
Price: $275
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NU05691
Product name: Uridine 5'-monophosphate
Packaging: 5G
Price: $250
Updated: 2021/12/16

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Uridine 5'-monophosphate Chemical Properties,Usage,Production

Description

Uridine 5'-monophosphateis a nucleotide that is synthesized from uridine. Uridine 5'-monophosphate has been shown to have anticancer activity in vitro and in vivo, as well as antiviral activity against herpes viruses. It is also used in foods such as infant formula to as a method of increasing uridine levels in blood.

Chemical Properties

(Uridine-3′-phosphate) Crystallizes in prisms from methanol. Freely soluble in water and alcohol; dextrorotatory in solution.

Uses

Uridine 5'-monophosphate is a nucleotide used as monomer in RNA. It is used in foods such as infant formula to as a method of increasing uridine levels in blood.

Uses

Biochemical research.

Application

Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.

Definition

The monophosphoric ester of uracil, i.e., the nucleotide containing uracil-d-ribose and phosphoric acid. The phosphate may be esterified to either the 2, 3, or 5 carbon of ribose, yielding uridine-2′-phosphate, uridine-3′phosphate, and uridine-5′-phosphate, respectively.

General Description

Uridine 5'-monophosphate acts as a precursor for all pyrimidine nucleotides.

Synthesis

56428-57-0

58-97-9

3803-29-0

The general procedure for the synthesis of ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyldihydrophosphoric acid and the compound (CAS: 3803-29-0) from the compound (CAS: 56428-57-0) was carried out as follows: selected activated nucleotides of a 15 mM solution and ImpN (N = A, U, C, G, dA) were dissolved in 1 M sodium fluoride (Sigma). The reaction mixtures were allowed to stand at 24°C for 8-10 days, during which time the progress of the reaction was monitored periodically by HPLC using a reversed-phase column. Upon completion of the reaction, each product mixture contained predominantly the corresponding fluorinated phosphate ester and a small amount of NMP hydrolysis product. Separation was carried out using a semipreparative reversed-phase Alltima C-18, 5 μm (10 mm × 300 mm) column (Alltech, Grace Davison) under isocratic elution conditions (88% aqueous 0.2% formic acid (Sigma) with 12% 30% acetonitrile). The flow rate was set at mL/min. the collected fractions were characterized by mass spectrometry.

References

[1] Tetrahedron Letters, 2014, vol. 55, # 8, p. 1464 - 1466

Uridine 5'-monophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

Disodium 5'-Inosinate

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Uridine 5'-monophosphate Suppliers

China 336 Europe 2 Germany 2 India 5 Italy 1 Switzerland 1 United Kingdom 4 United States 22 Global 373

WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?)

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Hangzhou Meiya Pharmaceutical Co.,ltd.

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Adamas Reagent, Ltd.

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Beijing Isomersyn Technology CO;LTD

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View Lastest Price from Uridine 5'-monophosphate manufacturers

WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?)

Product: Uridine 5'-monophosphate(UMP-H) 58-97-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: ≥99%
Supply Ability: 2tons
Release date: 2025-08-19

Hebei Chuanghai Biotechnology Co., Ltd

Product: Uridine 5’-monophosphte 58-97-9
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-01

Hangzhou Meiya Pharmaceutical Co Ltd

Product: Uridine 5’-monophosphte（UMP-H） 58-97-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: ≥98.0%
Supply Ability: 30 MT
Release date: 2024-02-06

58-97-9, Uridine 5'-monophosphateRelated Search:

Uridine 5′-monophosphate disodium salt 3'-Uridylic acid, disodium salt Uridine UTP URIDINE-13C9, 15N2-5 TRIPHOSPHATE SODI U DMT-2′O-TBDMS-rU Phosphoramidite UDP Guanosine-5'-diphosphate disodium salt UDPGA TRISODIUM SALT Uridine-5'-triphosphoric acid trisodium salt UDP-ALPHA-D-GALACTOSE DISODIUM SALT Uridine-5'-diphosphate disodium salt Uridine Diphosphate Choline Uridine Diphosphate Choline Ammonium Salt 2',3',5'-TRI-O-BENZOYLURIDINE Uridine-5-oxyacetic acid methyl ester Uridine Diphosphate-GlcNaz BPBNNONNJSGJLR-UHFFFAOYSA-L

U 5'-P

URIDINE-5'-PHOSPHATE

URIDYLIC ACID

5’-ump

ump(nucleicacid)

uridine5’-(dihydrogenphosphate)

uridine5’-phosphoricacid

uridinemonophosphate

UMP-H

Uridylic acid, 5'-Uridylic acid, Uridine phosphate, 5'-UMP, Uridine 5'-phosphoric acid

uridinephosphate

uridine 5-monophosphate free acid

Uridine Monophospahte

Uridine Monophosphate and salts

URIDINE-5'-MONOPHOSPHATE FREE ACID 98-100%

URIDINE-5'-MONOPHOSPHATE FREE ACID CELL CULTURE REAGENT 98-100%

98-100%

Uridine-5''-monophosphoric acid (and/or unspecified salts)

URIDINE 5''-MONOPHOSPHATE (UMP)

U 5μ-P, UMP, Uridylic acid

Urd-5'-P

5'-Uridylic acid (8ci)(9ci)

Uridylate

Uridine 5′-monophosphate,U 5′-P, UMP, Uridylic acid

uridine monophosphate {= UMP}

((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl dihydrogen phosphate

UMP.H2

[(2R,3S,4R,5R)-5-(2,4-dioxo-1-pyrimidinyl)-3,4-dihydroxy-2-oxolanyl]methyl phosphate

Uridine-5'-phosphate/UMP

Diquafosol Impurity 1(UMP Sodium Salt)

5'- uridine acid

Uridine 5’-monophosphte

5'-UMP·H2

Uridine-5-Monophosphat

Uridine 5'-monophosphate(UMP-H)

Uridine 5'-monophosphate Solution, 100μg/mL

UMP USP/EP/BP

5'-Uridylate monophosphate

{[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid

((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate

UMP, Uridine Monophosphate

UR, Uridine Monophosphate

Uridine 5′-monophosp

Uridine 5'-monophosphte(UMP-H)

UMP CAS

Uridine 5'-monophosphate (UMP-H)

Uridine 5'-monophosphate

5'-uridine

5'-Uridylic acid

Uridine 5'-monophosphte

uridine 3'-(dihydrogen phosphate)

Prinomastat Impurity 1

Uridine 5'-monophosphate【U1752】

Uridine 5'-monophosphate

58-97-9

58-97-7

BioChemical

Biochemicals and Reagents