Uridine-5'-triphosphoric acid trisodium salt
- Product Name
- Uridine-5'-triphosphoric acid trisodium salt
- CAS No.
- 19817-92-6
- Chemical Name
- Uridine-5'-triphosphoric acid trisodium salt
- Synonyms
- Diquafosol Impurity 5;UTP.2Na;utp na3;5'-UTP 3Na;UTP Na3，UTP;Utipina Hydrate;UTP, TrisodiuM S;NSC 20260 Hydrate;UTP-Na3，5‘-UTP-Na3;UTP, 100mM Solution
- CBNumber
- CB8853286
- Molecular Formula
- C9H16N2NaO15P3
- Formula Weight
- 508.14
- MOL File
- 19817-92-6.mol
Uridine-5'-triphosphoric acid trisodium salt Property
- Melting point:
- 140 °C
- Flash point:
- 113 °C
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- H2O: soluble25 mg of UTP in 0.5 ml of solvent, clear, colorless
- form
- Powder
- color
- White
- biological source
- yeast
- Water Solubility
- 75 g/100 mL (20 ºC)
- BRN
- 3585234
- InChI
- InChI=1/C9H15N2O15P3.Na.H/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;/t4-,6-,7-,8-;;/s3
- InChIKey
- IKVGSWYKOMJBSB-RFFBCSJBNA-N
- SMILES
- O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] |&1:1,2,3,19,r|
- CAS DataBase Reference
- 19817-92-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-68/20/21/22-68-36/37/38
- Safety Statements
- 22-26-36-36/37-24/25
- WGK Germany
- 1
- RTECS
- YU8083000
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- U6625
- Product name
- Uridine 5′-triphosphate trisodium salt hydrate
- Purity
- from yeast, Type III, ≥96%
- Packaging
- 25mg
- Price
- $37.1
- Updated
- 2025/07/31
- Product number
- U6625
- Product name
- Uridine 5′-triphosphate trisodium salt hydrate
- Purity
- from yeast, Type III, ≥96%
- Packaging
- 1g
- Price
- $688
- Updated
- 2025/07/31
- Product number
- 6701
- Product name
- Uridine-5′-triphosphate, Trisodium Salt
- Packaging
- 50 mg
- Price
- $85.6
- Updated
- 2025/07/31
- Product number
- U0022
- Product name
- Uridine 5'-Triphosphate Trisodium Salt Hydrate
- Purity
- >95.0%(HPLC)
- Packaging
- 100mg
- Price
- $43
- Updated
- 2021/12/16
- Product number
- 9003530
- Product name
- Uridine 5''-triphosphate (sodium salt)
- Packaging
- 500mg
- Price
- $70
- Updated
- 2024/03/01
Uridine-5'-triphosphoric acid trisodium salt Chemical Properties,Usage,Production
Description
Uridine-5'-triphosphoric acid trisodium salt, also known as UTP, is a polyphosphate analogue of uridine that is used in the synthesis of agonists at the G-protein-coupled P2Y receptors.
Chemical Properties
White crystalline powder
Uses
P2Y receptor agonist.
Uses
Uridine-5'-triphosphoric acid trisodium salt is a polyphosphate analogue of the nucleoside uridine used in the preparation of potent and selective agonists at the G-protein-coupled P2Y receptors.
Application
Uridine-5'-triphosphoric acid trisodium salt solution can be used to increase intracellular Ca2+ levels in rat primary tracheal epithelial cells. It is also used as a nucleotide substrate to analyze the activity of MutT homolog 1 (MTH1).
General Description
Uridine 5’-triphosphate trisodium salt (UTP-Na3) is not only an essential substance for intracellular RNA synthesis and energy metabolism, but also an important extracellular signaling molecule that finely regulates a variety of key physiological functions such as inflammation, tissue repair and secretion by activating P2Y receptors.
Biochem/physiol Actions
Uridine-5′-Triphosphate?(UTP) is a cytosolic nucleotide component of nucleic acids. It serves as a signaling molecule in the extracellular space. Uridine-5′-Triphosphate?(UTP) is involved in various pathophysiological responses in the nervous system.?UTP also plays a major role in the regeneration process.
in vitro
Uridine triphosphate (UTP) (0, 10, 100, 250, 500, and 1000 μM; 2, 4, 6, 8, 10, and 12 h) trisodium salt enhances RT4-D6P2T cells migration and wound repair. Uridine triphosphate trisodium salt induces Schwannoma cell migration through the activation of P2Y2 receptors and the increase of extracellular MMP-2 activation and expression. Uridine triphosphate (UTP) trisodium salt (Uridine-5'-triphosphoric acid trisodium salt) evokes MAPK phosphorylation in a biphasic pattern MAPK phosphorylation, with an early transient phosphorylation 5 min after treatment and a late and sustained phosphorylation that appeared at 6 h and lasted up to 24 h.
Structure and conformation
Uridine-5'-triphosphoric acid trisodium salt is composed of uridine (a nucleoside) combined with three phosphate groups and exists in the form of trisodium salt. This structure makes it well soluble in aqueous solution, and the negatively charged phosphate groups can participate in a variety of important energy transfer processes in biochemical reactions.
Uridine-5'-triphosphoric acid trisodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Uridine-5'-triphosphoric acid trisodium salt manufacturers
- Product
- Uridine triphosphate trisodium salt 19817-92-6
- Price
- US $590.00/g
- Min. Order
- 1g
- Purity
- 99 %
- Supply Ability
- 500 Kg
- Release date
- 2025-11-24
- Product
- Uridine 5’-triphosphate trisodium salt （UTP-Na3） 19817-92-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- ≥98%
- Supply Ability
- 2tons
- Release date
- 2025-08-19
- Product
- Uridine-5'-triphosphoric acid trisodium salt 19817-92-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-04-24