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Guanosine-5'-triphosphate disodium salt

Product Name
Guanosine-5'-triphosphate disodium salt
CAS No.
56001-37-7
Chemical Name
Guanosine-5'-triphosphate disodium salt
Synonyms
GTP;GTP DISODIUM SALT;GTP-Na2;GTP, 2NA;5'-GTP,2Na;GTP, NA2H2;5'-gtp-na2;Disodium 5′-GTP;GTP - lyophilized;Guanosine-5'-triphos
CBNumber
CB7261996
Molecular Formula
C10H17N5NaO14P3
Formula Weight
547.18
MOL File
56001-37-7.mol
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Guanosine-5'-triphosphate disodium salt Property

Melting point:
180°C
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
PBS (pH 7.2): 10 mg/ml
form 
Powder
color 
White
Water Solubility 
Soluble in water.
InChIKey
XIZYETZGWBYYEH-NGPBCCOENA-N
SMILES
O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=NC2C(NC(N)=NC1=2)=O)O.[NaH] |&1:1,2,3,19,r|
CAS DataBase Reference
56001-37-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-27-36/37/39-36
WGK Germany 
3
F 
10-21
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
51120
Product name
Guanosine 5′-triphosphate sodium salt hydrate
Purity
≥90% (HPLC)
Packaging
25 mg
Price
$67.8
Updated
2025/07/31
Sigma-Aldrich
Product number
51120
Product name
Guanosine 5′-triphosphate sodium salt hydrate
Purity
≥90% (HPLC)
Packaging
100 mg
Price
$167
Updated
2025/07/31
Sigma-Aldrich
Product number
51120
Product name
Guanosine 5′-triphosphate sodium salt hydrate
Purity
≥90% (HPLC)
Packaging
1 g
Price
$830
Updated
2025/07/31
Sigma-Aldrich
Product number
11140957001
Product name
GTP
Purity
=98% (HPLC), solution, pkg of 400?μL (100 mM; 40 μmol)
Packaging
400μL
Price
$137
Updated
2022/05/15
Cayman Chemical
Product number
16060
Product name
Guanosine 5′-triphosphate (sodium salt hydrate)
Packaging
50mg
Price
$67
Updated
2024/03/01
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Guanosine-5'-triphosphate disodium salt Chemical Properties,Usage,Production

Description

Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signalling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration.

Chemical Properties

White crystalline powder

Uses

A phosphoryl donor in protein synthesis and signal transduction

Uses

Guanosine-5'-triphosphate disodium salt, a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF). Guanosine 5-Triphosphate, Disodium Salt is a phosphoryl donor in protein synthesis and in signal transduction.

Application

Guanosine-5'-triphosphate disodium salt is a key nucleotide in RNA synthesis and cell signaling. It acts as an activator of G protein signaling and is involved in protein synthesis and signal transduction.

General Description

Guanosine5'-(tetrahydrogen triph) (GTP-Na2) is the disodium salt form of Guanosine triphosphate (GTP). GTP is a fundamental molecule in cellular biology, similar in importance to ATP (Adenosine triphosphate).

in vitro

Guanosine-5'-triphosphate disodium salt (500 μM, 24 hours) significantly promoted the upregulation of miR133a, miR133b, and myogenic regulatory factors Pax7, MyoD, and Myogenin in differentiated human myogenic precursor cells (MPCs).
Guanosine-5'-triphosphate disodium salt (5'-GTP trisodium salt) (500 μM, 24 h) can induce the release of exosomes from human myogenic progenitor cells.

Guanosine-5'-triphosphate disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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Guanosine-5'-triphosphate disodium salt Suppliers

Belgium 1 Canada 1 China 315 Europe 1 France 1 Germany 6 India 4 Japan 2 United Kingdom 10 United States 31 Global 372
Shanghai Peiling Biological Technology Co., LTD
Tel
13127581762 13127581762
Email
peilingchem@sina.com
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China
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Shanghai Amole Biotechnology Co., Ltd.
Tel
18916360931 18916360931
Email
2596183085@qq.com
Country
China
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
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China
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Hongene Biotech Corporation
Tel
021-64757213
Fax
86-21-64700613
Email
info@hongene.com
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China
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Beijing HwrkChemical Technology Co., Ltd
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18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
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China
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Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
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China
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12000
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Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
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Wuhan Wei Shunda Technology Development Co., Ltd.
Tel
86-027-88774375
Fax
86-027-88416321
Email
mwmwhot@163.com
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China
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View Lastest Price from Guanosine-5'-triphosphate disodium salt manufacturers

WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?)
Product
Guanosine5'-(tetrahydrogen triph) (GTP-Na2) 56001-37-7
Price
US $0.00-0.00/g
Min. Order
10g
Purity
≥95%
Supply Ability
2tons
Release date
2025-08-19
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Guanosine-5'-triphosphoric aicd disodium salt 56001-37-7
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
90%min
Supply Ability
500kg
Release date
2021-12-10
Hebei Chuanghai Biotechnology Co., Ltd
Product
GTP 2NA/Guanosine-5'-triphosphoric acid disodium salt 56001-37-7
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-04

56001-37-7, Guanosine-5'-triphosphate disodium salt Related Search:

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  • GUANOSINE-5'-TRIPHOSPHORIC ACID, DISODIUM
  • GUANOSINE 5'-TRIPHOSPHORIC ACID DISODIUM SALT
  • GUANOSINE-5'-TRIPHOSPHATE NA2-SALT
  • GUANOSINE-5'-TRIPHOSPHATE DISODIUM
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  • GTP DISODIUM SALT
  • Guanosine-5'-triphosphate disodium salt≥ 90% (HPLC)
  • GUANOSINE-5'-TRIPHOSPHATE DISODIUM SALT 95-98%
  • GUANOSINE-5'-TRIPHOSPHATE DISODIUM SALT 98+%
  • GUANOSINE 5'-TRIPHOSPHATE DISODIUM SALT HYDRATE 95%
  • guanosine 5'-(disodium dihydrogen triphosphate)
  • Guanosine 5'-triphosphate, disodium salt hydrate, for biochemistry, 95%
  • Guanosine 5-(tetrahydrogen triphosphate), disodium salt
  • 5'-gtp-na2
  • GUANOSINE-5''-TRIPHOSPHORIC AICD DISODIUM SALT
  • Guanosine 5'-triphosphate (GTP)
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  • Guanosine5'-(tetrahydrogen triphosphate), sodium salt
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  • Guanosine5'-(tetrahydrogen triph) (GTP-Na2)
  • Guanosine-5'-triphosphate Disodium Salt (~85%)
  • Gridine 5'-triphosphate disodium salt
  • Guanosine disodium triphosphate
  • ({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)(phosphonatooxy)phosphinate
  • Guanosine-5-Triphosphate Disodium Salt (5-GTP-Na2) extrapure, 90%
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