Uridine-5'-triphosphoric acid trisodium salt
- Product Name
- Uridine-5'-triphosphoric acid trisodium salt
- CAS No.
- 19817-92-6
- Chemical Name
- Uridine-5'-triphosphoric acid trisodium salt
- Synonyms
- Diquafosol Impurity 5;UTP.2Na;utp na3;5'-UTP 3Na;UTP Na3,UTP;Utipina Hydrate;UTP, TrisodiuM S;NSC 20260 Hydrate;UTP-Na3,5‘-UTP-Na3;UTP, 100mM Solution
- CBNumber
- CB8853286
- Molecular Formula
- C9H16N2NaO15P3
- Formula Weight
- 508.14
- MOL File
- 19817-92-6.mol
Uridine-5'-triphosphoric acid trisodium salt Property
- Melting point:
- 140 °C
- Flash point:
- 113 °C
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- H2O: soluble25 mg of UTP in 0.5 ml of solvent, clear, colorless
- form
- Powder
- color
- White
- Water Solubility
- 75 g/100 mL (20 ºC)
- BRN
- 3585234
- InChI
- InChI=1/C9H15N2O15P3.Na.H/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;/t4-,6-,7-,8-;;/s3
- InChIKey
- IKVGSWYKOMJBSB-RFFBCSJBNA-N
- SMILES
- O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] |&1:1,2,3,19,r|
- CAS DataBase Reference
- 19817-92-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-68/20/21/22-68-36/37/38
- Safety Statements
- 22-26-36-36/37-24/25
- WGK Germany
- 1
- RTECS
- YU8083000
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- U6625
- Product name
- Uridine 5′-triphosphate trisodium salt hydrate
- Purity
- from yeast, Type III, ≥96%
- Packaging
- 25mg
- Price
- $36.1
- Updated
- 2024/03/01
- Product number
- U6625
- Product name
- Uridine 5′-triphosphate trisodium salt hydrate
- Purity
- from yeast, Type III, ≥96%
- Packaging
- 1g
- Price
- $669
- Updated
- 2024/03/01
- Product number
- U0022
- Product name
- Uridine 5'-Triphosphate Trisodium Salt Hydrate
- Purity
- >95.0%(HPLC)
- Packaging
- 100mg
- Price
- $43
- Updated
- 2021/12/16
- Product number
- J23160
- Product name
- Uridine-5'-triphosphate trisodium salt hydrate, 90+%
- Purity
- Thermo Scientific
- Packaging
- 100mg
- Price
- $45.5
- Updated
- 2021/12/16
- Product number
- J23160
- Product name
- Uridine-5'-triphosphate trisodium salt hydrate, 90+%
- Purity
- Thermo Scientific
- Packaging
- 1g
- Price
- $224.97
- Updated
- 2021/12/16
Uridine-5'-triphosphoric acid trisodium salt Chemical Properties,Usage,Production
Description
Uridine-5'-triphosphoric acid trisodium salt, also known as UTP, is a polyphosphate analogue of uridine that is used in the synthesis of agonists at the G-protein-coupled P2Y receptors.
Chemical Properties
White crystalline powder
Uses
psychostimulant
Uses
P2Y receptor agonist.
Uses
Uridine-5'-triphosphoric acid trisodium salt is a polyphosphate analogue of the nucleoside uridine used in the preparation of potent and selective agonists at the G-protein-coupled P2Y receptors.
Application
Uridine-5'-triphosphoric acid trisodium salt solution can be used to increase intracellular Ca2+ levels in rat primary tracheal epithelial cells. It is also used as a nucleotide substrate to analyze the activity of MutT homolog 1 (MTH1).
Biochem/physiol Actions
Uridine-5′-Triphosphate?(UTP) is a cytosolic nucleotide component of nucleic acids. It serves as a signaling molecule in the extracellular space. Uridine-5′-Triphosphate?(UTP) is involved in various pathophysiological responses in the nervous system.?UTP also plays a major role in the regeneration process.
in vitro
Uridine triphosphate (UTP) (0, 10, 100, 250, 500, and 1000 μM; 2, 4, 6, 8, 10, and 12 h) trisodium salt enhances RT4-D6P2T cells migration and wound repair. Uridine triphosphate trisodium salt induces Schwannoma cell migration through the activation of P2Y2 receptors and the increase of extracellular MMP-2 activation and expression. Uridine triphosphate (UTP) trisodium salt (Uridine-5'-triphosphoric acid trisodium salt) evokes MAPK phosphorylation in a biphasic pattern MAPK phosphorylation, with an early transient phosphorylation 5 min after treatment and a late and sustained phosphorylation that appeared at 6 h and lasted up to 24 h.
Uridine-5'-triphosphoric acid trisodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
Uridine-5'-triphosphoric acid trisodium salt Suppliers
- Tel
- --
- Fax
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- export@ecochem.dk
- Country
- Europe
- ProdList
- 6371
- Advantage
- 66
- Tel
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- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
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- Advantage
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View Lastest Price from Uridine-5'-triphosphoric acid trisodium salt manufacturers
- Product
- Uridine-5'-triphosphoric acid trisodium salt 19817-92-6
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-12-20
- Product
- Uridine-5'-triphosphoric acid trisodium salt 19817-92-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2024-09-05
- Product
- Uridine 5’-triphosphate trisodium salt; UTP-Na3,5‘-UTP-Na3 19817-92-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 95.0%min. HPLC
- Supply Ability
- 10000kg
- Release date
- 2022-11-07