Uridine-5'-triphosphoric acid trisodium salt

Product Name: Uridine-5'-triphosphoric acid trisodium salt
CAS No.: 19817-92-6
Chemical Name: Uridine-5'-triphosphoric acid trisodium salt
Synonyms: Diquafosol Impurity 5;UTP.2Na;utp na3;5'-UTP 3Na;UTP Na3，UTP;Utipina Hydrate;UTP, TrisodiuM S;NSC 20260 Hydrate;UTP-Na3，5‘-UTP-Na3;UTP, 100mM Solution
CBNumber: CB8853286
Molecular Formula: C9H16N2NaO15P3
Formula Weight: 508.14
MOL File: 19817-92-6.mol

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Uridine-5'-triphosphoric acid trisodium salt Property

Melting point:: 140 °C
Flash point:: 113 °C
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: H2O: soluble25 mg of UTP in 0.5 ml of solvent, clear, colorless
form: Powder
color: White
Water Solubility: 75 g/100 mL (20 ºC)
BRN: 3585234
InChI: InChI=1/C9H15N2O15P3.Na.H/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;/t4-,6-,7-,8-;;/s3
InChIKey: IKVGSWYKOMJBSB-RFFBCSJBNA-N
SMILES: O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] |&1:1,2,3,19,r|
CAS DataBase Reference: 19817-92-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-68/20/21/22-68-36/37/38
Safety Statements: 22-26-36-36/37-24/25
WGK Germany: 1
RTECS: YU8083000
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: U6625
Product name: Uridine 5′-triphosphate trisodium salt hydrate
Purity: from yeast, Type III, ≥96%
Packaging: 25mg
Price: $36.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: U6625
Product name: Uridine 5′-triphosphate trisodium salt hydrate
Purity: from yeast, Type III, ≥96%
Packaging: 1g
Price: $669
Updated: 2024/03/01

TCI Chemical

Product number: U0022
Product name: Uridine 5'-Triphosphate Trisodium Salt Hydrate
Purity: >95.0%(HPLC)
Packaging: 100mg
Price: $43
Updated: 2021/12/16

Alfa Aesar

Product number: J23160
Product name: Uridine-5'-triphosphate trisodium salt hydrate, 90+%
Purity: Thermo Scientific
Packaging: 100mg
Price: $45.5
Updated: 2021/12/16

Alfa Aesar

Product number: J23160
Product name: Uridine-5'-triphosphate trisodium salt hydrate, 90+%
Purity: Thermo Scientific
Packaging: 1g
Price: $224.97
Updated: 2021/12/16

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Uridine-5'-triphosphoric acid trisodium salt Chemical Properties,Usage,Production

Description

Uridine-5'-triphosphoric acid trisodium salt, also known as UTP, is a polyphosphate analogue of uridine that is used in the synthesis of agonists at the G-protein-coupled P2Y receptors.

Chemical Properties

White crystalline powder

Uses

psychostimulant

Uses

P2Y receptor agonist.

Uses

Uridine-5'-triphosphoric acid trisodium salt is a polyphosphate analogue of the nucleoside uridine used in the preparation of potent and selective agonists at the G-protein-coupled P2Y receptors.

Application

Uridine-5'-triphosphoric acid trisodium salt solution can be used to increase intracellular Ca2+ levels in rat primary tracheal epithelial cells. It is also used as a nucleotide substrate to analyze the activity of MutT homolog 1 (MTH1).

Biochem/physiol Actions

Uridine-5′-Triphosphate?(UTP) is a cytosolic nucleotide component of nucleic acids. It serves as a signaling molecule in the extracellular space. Uridine-5′-Triphosphate?(UTP) is involved in various pathophysiological responses in the nervous system.?UTP also plays a major role in the regeneration process.

in vitro

Uridine triphosphate (UTP) (0, 10, 100, 250, 500, and 1000 μM; 2, 4, 6, 8, 10, and 12 h) trisodium salt enhances RT4-D6P2T cells migration and wound repair. Uridine triphosphate trisodium salt induces Schwannoma cell migration through the activation of P2Y2 receptors and the increase of extracellular MMP-2 activation and expression. Uridine triphosphate (UTP) trisodium salt (Uridine-5'-triphosphoric acid trisodium salt) evokes MAPK phosphorylation in a biphasic pattern MAPK phosphorylation, with an early transient phosphorylation 5 min after treatment and a late and sustained phosphorylation that appeared at 6 h and lasted up to 24 h.

Uridine-5'-triphosphoric acid trisodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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Uridine-5'-triphosphoric acid trisodium salt Suppliers

Belgium 1 Canada 1 China 393 Europe 2 France 1 Germany 7 India 7 Italy 1 Japan 1 Switzerland 1 United Kingdom 8 United States 38 Global 461

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View Lastest Price from Uridine-5'-triphosphoric acid trisodium salt manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Uridine 5’-triphosphate trisodium salt； UTP-Na3，5‘-UTP-Na3 19817-92-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 95.0%min. HPLC
Supply Ability: 10000kg
Release date: 2022-11-07

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Uridine-5'-triphosphoric acid trisodium salt 19817-92-6
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-20

Watson Biotechnology Co.,Ltd

Product: Uridine-5'-triphosphoric acid trisodium salt 19817-92-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2024-09-05

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