8α-(2-Methylacryloyloxy) hirsutinolide 13-O-acetate

Product Name: 8α-(2-Methylacryloyloxy) hirsutinolide 13-O-acetate
CAS No.: 67667-71-4
Chemical Name: 8α-(2-Methylacryloyloxy) hirsutinolide 13-O-acetate
Synonyms: 8α-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate;8α-(2-Methylacryloyloxy) hirsutinolide 13-O-acetate;8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate;[(1R,2E,8S,10R,11S)-6-(Acetyloxymethyl)-11-hydroxy-1,10-dimethyl-5-oxo-4,14-dioxatricyclo[9.2.1.03,7]tetradeca-2,6-dien-8-yl] 2-meth ylprop-2-enoate;2-Propenoic acid, 2-methyl-, (4S,6R,7S,10R,11E)-3-[(acetyloxy)methyl]-2,4,5,6,7,8,9,10-octahydro-7-hydroxy-6,10-dimethyl-2-oxo-7,10-epoxycyclodeca[b]furan-4-yl ester
CBNumber: CB12725364
Molecular Formula: C21H26O8
Formula Weight: 406.43
MOL File: 67667-71-4.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot

Product number: CD32000645
Product name: 8α-(2-Methylacryloyloxy)hirsutinolide13-O-acetate
Purity: 95+%
Packaging: 5mg
Price: $802
Updated: 2021/12/16

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8α-(2-Methylacryloyloxy) hirsutinolide 13-O-acetate Chemical Properties,Usage,Production

Uses

8α-(2-Methylacryloyloxy)-hirsutinolide-13-O-acetate is an irreversible CYP2A6 inhibitor with IC50s of 8.64 μM and 22.3 μM with pre-incubation and co-incubaition, respectively. 8α-(2-Methylacryloyloxy)-hirsutinolide-13-O-acetate also inhibits MAO-A and MAO-B with IC50s of 60.2 and 38.6 μM, respectively[1].

References

[1] Prasopthum A, et al. Inhibition effects of Vernonia cinerea active compounds against cytochrome P450 2A6 and human monoamine oxidases, possible targets for reduction of tobacco dependence. Drug Metab Pharmacokinet. 2015 Apr;30(2):174-81. DOI:10.1016/j.dmpk.2014.12.005

8α-(2-Methylacryloyloxy) hirsutinolide 13-O-acetate Preparation Products And Raw materials

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8α-(2-Methylacryloyloxy) hirsutinolide 13-O-acetate Suppliers

China 13 United States 4 Global 17

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8α-(2-Methylacryloyloxy) hirsutinolide 13-O-acetate

8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate

2-Propenoic acid, 2-methyl-, (4S,6R,7S,10R,11E)-3-[(acetyloxy)methyl]-2,4,5,6,7,8,9,10-octahydro-7-hydroxy-6,10-dimethyl-2-oxo-7,10-epoxycyclodeca[b]furan-4-yl ester

8α-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate

[(1R,2E,8S,10R,11S)-6-(Acetyloxymethyl)-11-hydroxy-1,10-dimethyl-5-oxo-4,14-dioxatricyclo[9.2.1.03,7]tetradeca-2,6-dien-8-yl] 2-meth ylprop-2-enoate

67667-71-4