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TCO-carbonate

Product Name
TCO-carbonate
CAS No.
1191901-33-3
Chemical Name
TCO-carbonate
Synonyms
TCO-NHS;TCO-carbonate;TCO-NHS ester;(4E)-TCO-NHS ester;1191901-33-3(Mixture);TCONHS ester,TCO NHS ester;TCO-N-hydroxysuccinimidyl carbonate;TCO4 - NHS carbonate / AXIAL isomer;TCO4 - NHS carbonate / EQUATORIAL isomer;TCO-NHS Ester,Trans-Cyclooctene-NHS ester
CBNumber
CB12755772
Molecular Formula
C13H17NO5
Formula Weight
267.28
MOL File
1191901-33-3.mol
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TCO-carbonate Property

Melting point:
90-105°C
Boiling point:
369.1±45.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to off-white
InChI
InChI=1S/C13H17NO5/c15-11-8-9-12(16)14(11)19-13(17)18-10-6-4-2-1-3-5-7-10/h1-2,10H,3-9H2/b2-1+
InChIKey
OUGQJOKGFAIFAQ-OWOJBTEDSA-N
SMILES
C(ON1C(=O)CCC1=O)(=O)OC1CCCC=CCC1 |t:16|
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
764523
Product name
(E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate
Packaging
1mg
Price
$76.9
Updated
2024/03/01
Sigma-Aldrich
Product number
764523
Product name
(E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate
Packaging
5mg
Price
$249
Updated
2024/03/01
Sigma-Aldrich
Product number
764523
Product name
(E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate
Packaging
25mg
Price
$548
Updated
2024/03/01
TRC
Product number
T126088
Product name
TCO-NHSester
Packaging
10mg
Price
$200
Updated
2021/12/16
BroadPharm
Product number
BP-22417
Product name
TCO-NHSester
Purity
95%
Packaging
25mg
Price
$145
Updated
2021/12/16
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TCO-carbonate Chemical Properties,Usage,Production

Description

TCO-NHS Ester is an popular reagent to label amine-containing compound or biomolecule, TCOI enable fast click chemistry with tetrazine.

Uses

Succinimidyl carbonate/NHS functionalized cyclooctene derivative for incorporation of the cyclooctene moiety into amine containing compounds or biomolecules. Cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1,2,4,5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.

TCO-carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

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TCO-carbonate Suppliers

Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4825
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7887
Advantage
56
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16684
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28806
Advantage
58
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20)
Fax
0539-6362799(To 20)
Country
China
ProdList
9998
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-638-7771 18920564737
Email
sales@heowns.com
Country
China
ProdList
22888
Advantage
60
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
Email
3001379618@qq.com
Country
China
ProdList
10384
Advantage
58
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View Lastest Price from TCO-carbonate manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
(4E)-TCO-NHS ester 1191901-33-3
Price
US $0.00/mg
Min. Order
25mg
Purity
>95.00%
Supply Ability
25mg
Release date
2024-03-21

1191901-33-3, TCO-carbonateRelated Search:


  • (E)-4-Cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl ester carbonic acid
  • (E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate
  • TCO-carbonate
  • TCO-NHS
  • TCO-N-hydroxysuccinimidyl carbonate
  • trans-4-Cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl carbonate
  • TCO-NHS ester
  • TCO4 - NHS carbonate / EQUATORIAL isomer
  • TCO4 - NHS carbonate / AXIAL isomer
  • (4E)-TCO-NHS ester
  • TCO-NHS Ester,Trans-Cyclooctene-NHS ester
  • Carbonic acid, (4E)-4-cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl ester
  • 1191901-33-3(Mixture)
  • (E)-Cyclooct-4-en-1-yl (2,5-dioxopyrrolidin-1-yl) carbonate
  • TCONHS ester,TCO NHS ester
  • TCO-NHS/Carbonic acid, (4E)-4-cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl ester
  • (E)-4-Cycloocten-1-yl (2,5-Dioxo-1-pyrrolidinyl) Carbonate
  • (4Z)-cyclooct-4-en-1-yl 2,5-dioxopyrrolidin-1-yl carbonate
  • 1191901-33-3
  • 119190-33-3
  • SiChem