ChemicalBook > CAS DataBase List > DIPHENYLAMINE HYDROCHLORIDE

DIPHENYLAMINE HYDROCHLORIDE

Product Name
DIPHENYLAMINE HYDROCHLORIDE
CAS No.
537-67-7
Chemical Name
DIPHENYLAMINE HYDROCHLORIDE
Synonyms
DiphenylamineHCl;diphenylammonium chloride;DIPHENYLAMINE HYDROCHLORIDE;DiphenylaMine Hydrochlori...;N-PHENYLANILINE HYDROCHLORIDE;Diphenylamine Hydrochloride >Diphenylamine hydrochloride,99%;n-phenyl-benzenaminhydrochloride;Diphenylamine hydrochloride,≥99.0%;Benzenamine, N-phenyl-,hydrochloride (1:1)
CBNumber
CB1278532
Molecular Formula
C12H12ClN
Formula Weight
205.68
MOL File
537-67-7.mol
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DIPHENYLAMINE HYDROCHLORIDE Property

Melting point:
180 °C
storage temp. 
<0°C
form 
powder to crystal
color 
White to Almost white
InChIKey
JEFJSEIUEJBMSR-UHFFFAOYSA-N
CAS DataBase Reference
537-67-7(CAS DataBase Reference)
EPA Substance Registry System
Benzenamine, N-phenyl-, hydrochloride (537-67-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
HS Code 
2921.44.7000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D0874
Product name
Diphenylamine Hydrochloride
Purity
>99.0%(HPLC)(N)
Packaging
25g
Price
$52
Updated
2025/07/31
TRC
Product number
D492845
Product name
Diphenylamine Hydrochloride
Packaging
500mg
Price
$60
Updated
2021/12/16
TRC
Product number
D492845
Product name
Diphenylamine Hydrochloride
Packaging
2.5g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
7678AB
Product name
Diphenylamine Hydrochloride
Packaging
25g
Price
$116
Updated
2021/12/16
Alichem
Product number
537677
Product name
Diphenylamine Hydrochloride
Packaging
500g
Price
$439.04
Updated
2021/12/16
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DIPHENYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

Diphenylamine hydrochloride (N-Phenylaniline hydrochloride) is an antihyperglycemic agent with oral activity and a common structure in non-steroidal anti-inflammatory drugs (NSAIDs) that uncouples oxidative phosphorylation in mitochondria, leading to a decrease in hepatic cell ATP levels and causing liver cell damage. Diphenylamine hydrochloride is also an industrial antioxidant, a dyeing mordant, and is used in agriculture as an antifungal and antibacterial agent[1][2][3][4].

in vivo

Diphenylamine hydrochloride is excreted in rats through urine and bile[1].
Diphenylamine (10 mg/kg, orally, single dose) hydrochloride lowers blood sugar in hyperglycemic rabbits[2].

Animal Model:Hyperglycemic rabbit[2]
Dosage:10 mg/kg; single dose
Administration:Oral
Result:Reduced blood sugar by 61.4% two hours after administration.

References

[1] W E Alexander, et al. Metabolism of diphenylamine in the rat, rabbit and man. Food Cosmet Toxicol. 1965 Oct;3(4):571-9. DOI:10.1016/s0015-6264(65)80203-6
[2] M S Karawya, wt al. Diphenylamine, an antihyperglycemic agent from onion and tea. J Nat Prod. 1984 Sep-Oct;47(5):775-80. DOI:10.1021/np50035a003
[3] Safe S, et al. Identification of toxic impurities in commercial diphenylamine. Bull Environ Contam Toxicol. 1977 Feb;17(2):204-7. DOI:10.1007/BF01685551
[4] Masubuchi Y, et al. Possible mechanism of hepatocyte injury induced by diphenylamine and its structurally related nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther. 2000 Mar;292(3):982-7. PMID:10688613

DIPHENYLAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from DIPHENYLAMINE HYDROCHLORIDE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
DIPHENYLAMINE HYDROCHLORIDE 537-67-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

537-67-7, DIPHENYLAMINE HYDROCHLORIDERelated Search:


  • N-PHENYLANILINE HYDROCHLORIDE
  • Diphenylamine hydrochloride,99%
  • DiphenylaMine Hydrochlori...
  • DIPHENYLAMINE HYDROCHLORIDE
  • n-phenyl-benzenaminhydrochloride
  • diphenylammonium chloride
  • DiphenylamineHCl
  • 2-propenoic acid 1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-2-yl ester
  • Diphenylamine Hydrochloride &gt
  • DIPHENYLAMINE HYDROCHLORIDE ISO 9001:2015 REACH
  • Diphenylamine hydrochloride,≥99.0%
  • Benzenamine, N-phenyl-,hydrochloride (1:1)
  • Diphenylamine Hydrochloride, 10 mM in DMSO
  • 537-67-7
  • C12H11NHCl
  • C12H11NHCI