ChemicalBook > CAS DataBase List > 3-Aminoisonicotinic acid

3-Aminoisonicotinic acid

Product Name
3-Aminoisonicotinic acid
CAS No.
7579-20-6
Chemical Name
3-Aminoisonicotinic acid
Synonyms
3-Aminopyridine-4-carboxylic acid;3-Amino-4-picolin;BUTTPARK 43\57-53;TIMTEC-BB SBB002130;3-Aminoisonicotinic acid;3-AminoisonicotinicAcid>3-AMino-4-pyridinecarboxylic;3-Aminoisonicotinic acid ,97%;3-Aminopyridin-4-carboxylic acid;3-AMINO-4-PYRIDINECARBOXYLIC ACID
CBNumber
CB1280483
Molecular Formula
C6H6N2O2
Formula Weight
138.12
MOL File
7579-20-6.mol
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3-Aminoisonicotinic acid Property

Melting point:
300°C
Boiling point:
497.1±30.0 °C(Predicted)
Density 
1.417±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Water
form 
Solid
pka
2.69±0.10(Predicted)
color 
Yellow to Brown
InChIKey
FYEQKMAVRYRMBL-UHFFFAOYSA-N
CAS DataBase Reference
7579-20-6(CAS DataBase Reference)
NIST Chemistry Reference
4-Pyridinecarboxylic acid, 3-amino-(7579-20-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
710849
Product name
3-Aminopyridine-4-carboxylic acid
Purity
95%
Packaging
1g
Price
$17.3
Updated
2025/07/31
TCI Chemical
Product number
A2133
Product name
3-Aminoisonicotinic Acid
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$81
Updated
2025/07/31
TCI Chemical
Product number
A2133
Product name
3-Aminoisonicotinic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$271
Updated
2025/07/31
TRC
Product number
A611745
Product name
3-Aminoisonicotinic Acid
Packaging
1g
Price
$65
Updated
2021/12/16
AK Scientific
Product number
J92072
Product name
3-Aminopyridine-4-carboxylic acid
Packaging
1g
Price
$10
Updated
2021/12/16
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3-Aminoisonicotinic acid Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

3-Aminoisonicotinic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

4664-01-1

7579-20-6

The general procedure for the synthesis of 3-aminoisonicotinic acid from 3,4-pyridinedicarboximide is as follows: Step 1: Bromine (1.93 mL, 38.6 mmol) was slowly added to a 10% aqueous sodium hydroxide solution (100 mL) followed by 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-dione (5.20 g, 35.1 mmol) under ice-bath cooling conditions. Next, 10% aqueous sodium hydroxide solution (60 mL) was added to the reaction mixture and the mixture was heated and stirred at 90 °C for 40 min. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted with 50% sulfuric acid to 3. The precipitated solid was collected by filtration and washed with water to afford 3-aminoisonicotinic acid in the form of a light yellow powder (5.00 g, 100% yield). The product was characterized by 1H-NMR (200 MHz, DMSO-d6): δ 7.46 (1H, d, J = 5.1 Hz), 7.73 (1H, d, J = 5.1 Hz), 8.21 (1H, s).

References

[1] Patent: US2015/329556, 2015, A1. Location in patent: Paragraph 1612-1614
[2] Bioorganic and Medicinal Chemistry, 2001, vol. 9, # 8, p. 2061 - 2071
[3] Australian Journal of Chemistry, 1993, vol. 46, # 7, p. 987 - 993
[4] Tetrahedron Letters, 1993, vol. 34, # 39, p. 6225 - 6228
[5] Patent: US2006/199804, 2006, A1. Location in patent: Page/Page column 29

3-Aminoisonicotinic acid Preparation Products And Raw materials

Raw materials

Acetic anhydride Acetamide 3,4-Pyridinedicarboxylic acid Bromine Acetic acid Sodium hydroxide

Preparation Products

3-AMINO-2-CHLORO-ISONICOTINAMIDE 3-AMINO-2-CHLORO-ISONICOTINIC ACID METHYL ESTER
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View Lastest Price from 3-Aminoisonicotinic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
3-Aminoisonicotinic acid 7579-20-6
Price
US $8.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2025-03-12
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-Aminoisonicotinic acid 7579-20-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
3-Aminoisonicotinic acid 7579-20-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2018-08-21

7579-20-6, 3-Aminoisonicotinic acidRelated Search:

2-Picolinic acid 2-Aminopyridine 3-Aminopyridine Ethyl 2-(Chlorosulfonyl)acetate 3-Amino-2-pyridinecarboxylic acid Chromium picolinate Glycine 4-Dimethylaminopyridine Folic acid Quinolinic acid 2,5-PYRIDINEDICARBOXYLIC ACID Citric acid Ascoric Acid 2-AMINO PYRIDINE-4-CARBOXYLIC ACID / 2-AMINOISONICOTINIC ACID,2-AMINOISONICOTINIC ACID Ethyl 2-Aminoisonicotinate 3-AMINO-ISONICOTINIC ACID METHYL ESTER 5-Aminopyridine-2-carboxylic Acid Talniflumate

  • TIMTEC-BB SBB002130
  • BUTTPARK 43\57-53
  • 4-PYRIDINECARBOXYLIC ACID, 3-AMINO-
  • 3-AMINO-4-PYRIDINECARBOXYLIC ACID
  • 3-AMINOPYRIDINE-4-CARBOXYLICACID 95+%
  • 3-Amino-4-picolin
  • 3-aminoisonicotinic acid hydrochloride
  • 4-Pyridinecarboxylicacid,3-amino-(9CI)
  • 3-Amino-4-methylpyridine carboxylic acid
  • 3-AMINO-4-PYRIDINECARBOXYLIC ACID / 3-AMINOISONICOTINIC ACID
  • 3-Aminoisonicotinic acid
  • 3-Aminopyridine-4-carboxylic acid
  • 3-AMINOPYRIDINE-4-CARBOXYLICACID 95%
  • 3-Aminoisonicotinic acid ,97%
  • 3-AMino-4-pyridinecarboxylic
  • 3-aMino-4-carboxylic acid pyridine
  • 3-Aminopyridine-4-carboxylic acid, 3-Amino-4-carboxypyridine
  • 3-AminoisonicotinicAcid&gt
  • 3-Aminoisonicotinic acid USP/EP/BP
  • 3-Aminopyridin-4-carboxylic acid
  • 7579-20-6
  • Chemical Amines
  • Carboxylic Acids
  • pharmacetical
  • Carboxylic Acids
  • Organic acids
  • Amino Acids and Derivatives
  • Heterocycles
  • Pyridine
  • pyridine derivative
  • AMINOACID
  • Amines
  • blocks
  • Carboxes
  • Pyridines
  • Pyridine series