3-Amino-2-pyridinecarboxylic acid
- Product Name
- 3-Amino-2-pyridinecarboxylic acid
- CAS No.
- 1462-86-8
- Chemical Name
- 3-Amino-2-pyridinecarboxylic acid
- Synonyms
- 3-AMINOPICOLINIC ACID;3-AMINO-PYRIDINE-2-CARBOXYLIC ACID;2-Pyridinecarboxylic acid, 3-amino-;AKOS 92172;H-3APC2-OH;IFLAB-BB F2113-0045;RARECHEM AQ NN 0176;3-AMINO-2-PICOLINIC ACID;3-Amino-α-picolinic acid;3-Amino-2-carboxypyridine
- CBNumber
- CB1487480
- Molecular Formula
- C6H6N2O2
- Formula Weight
- 138.12
- MOL File
- 1462-86-8.mol
3-Amino-2-pyridinecarboxylic acid Property
- Melting point:
- 218-220
- Boiling point:
- 386.6±27.0 °C(Predicted)
- Density
- 1.417±0.06 g/cm3(Predicted)
- RTECS
- US5175000
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- Soluble in acetone, ethanol and methanol.
- pka
- 1.32±0.50(Predicted)
- form
- Solid
- color
- Yellow to pale brown
- InChI
- InChI=1S/C6H6N2O2/c7-4-2-1-3-8-5(4)6(9)10/h1-3H,7H2,(H,9,10)
- InChIKey
- BOOMHTFCWOJWFO-UHFFFAOYSA-N
- SMILES
- C1(C(O)=O)=NC=CC=C1N
- CAS DataBase Reference
- 1462-86-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A627800
- Product name
- 3-AminopicolinicAcid
- Packaging
- 5G
- Price
- $90
- Updated
- 2021/12/16
- Product number
- A1379-99
- Product name
- 3-Aminopicolinic Acid
- Packaging
- 5g
- Price
- $326
- Updated
- 2021/12/16
- Product number
- 046510
- Product name
- 3-Amino-2-pyridinecarboxylicacid
- Purity
- 97%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- J53463
- Product name
- 3-Amino-2-pyridinecarboxylicacid
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
- Product number
- 046510
- Product name
- 3-Amino-2-pyridinecarboxylicacid
- Purity
- 97%
- Packaging
- 5g
- Price
- $24
- Updated
- 2021/12/16
3-Amino-2-pyridinecarboxylic acid Chemical Properties,Usage,Production
Chemical Properties
Green/Brown Crystals
Uses
Employed as an important intermediate for syntheses material and pharmaceutical.
Uses
3-Amino-2-pyridinecarboxylic acid is a useful synthetic intermediate.
Application
3-Aminopicolinic Acid is used in the preparation of piperidinyl-methyl-purinamines as NSD2 inhibitors and anti-cancer agents.
Synthesis
59290-85-6
1462-86-8
(2) Preparation of 3-aminopyridine-2-carboxylic acid: 3-nitropyridine-2-carboxylic acid (2.72 g, 16.2 mmol) and sodium bicarbonate (1.34 g, 16.2 mmol) were dissolved in distilled water (20 mL). The atmosphere in the system was replaced with nitrogen to exclude oxygen. After adding 10% palladium carbon catalyst (1.72 g), the atmosphere in the system was replaced with hydrogen and the reaction was stirred at room temperature for 50 hours. After completion of the reaction, the pH of the reaction solution was adjusted to weakly acidic by adding 1N aqueous hydrochloric acid. The solvent was removed by distillation under reduced pressure and a small amount of ethanol and ethyl acetate was added to the residue and the resulting precipitate was collected by filtration. The filtrate was concentrated to afford the target product 3-aminopyridine-2-carboxylic acid (1.50 g, 67% yield) as a light yellow solid.
References
[1] Patent: US2005/182045, 2005, A1. Location in patent: Page/Page column 74
3-Amino-2-pyridinecarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Amino-2-pyridinecarboxylic acid manufacturers
- Product
- 3-Amino-2-pyridinecarboxylic acid 1462-86-8
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-29
- Product
- 3-Amino-2-pyridinecarboxylic acid 1462-86-8
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2018-12-22