ChemicalBook > CAS DataBase List > Triclabendazole

Triclabendazole

Product Name
Triclabendazole
CAS No.
68786-66-3
Chemical Name
Triclabendazole
Synonyms
Triclabendazol;Tricalbendazole;6-CHLORO-5-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-BENZIMIDAZOLE;FASINEX;CGA-89317;snalvbendaz;TRICLABENDAZOLE;CGA-89317, Egaten;Triclabendazole EP;Triclabendazole CRS
CBNumber
CB1282896
Molecular Formula
C14H9Cl3N2OS
Formula Weight
359.66
MOL File
68786-66-3.mol
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Triclabendazole Property

Melting point:
175-176°C
Boiling point:
240.6°C (rough estimate)
Density 
1.3875 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Acetonitrile (Slightly, Sonicated), Methanol (Slightly)
form 
Solid
pka
7.91±0.10(Predicted)
color 
White to Beige
Merck 
14,9652
BCS Class
4/3
Stability:
Stability
InChI
InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
InChIKey
NQPDXQQQCQDHHW-UHFFFAOYSA-N
SMILES
C1(SC)NC2=CC(Cl)=C(OC3=CC=CC(Cl)=C3Cl)C=C2N=1
CAS DataBase Reference
68786-66-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
RTECS 
DD6747000
HS Code 
29339900
Toxicity
LD50 oral in rabbit: 206mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001737
Product name
Triclabendazole
Purity
EuropePharmacopoeia (EP) Reference Standard
Packaging
y0001737
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0001723
Product name
Triclabendazole for system suitability
Purity
EuropePharmacopoeia (EP) Reference Standard
Packaging
y0001723
Price
$153
Updated
2024/03/01
TCI Chemical
Product number
T2826
Product name
Triclabendazole
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$29
Updated
2024/03/01
TCI Chemical
Product number
T2826
Product name
Triclabendazole
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$79
Updated
2024/03/01
Cayman Chemical
Product number
18883
Product name
Triclabendazole
Purity
≥98%
Packaging
1g
Price
$72
Updated
2024/03/01
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Triclabendazole Chemical Properties,Usage,Production

Description

Triclabendazole is a benzimidazole anthelmintic. It eliminates both immature and adult flukes in a sheep model of F. hepatica infection when administered at a dose of 10 mg/kg. Triclabendazole (5 μM) also protects against glucose- or α-synuclein-induced apoptosis in S. cerevisiae via inhibition of adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A (PKA) nutrient sensing pathway.

Chemical Properties

Off-White Solid

Uses

Triclabendazole is classified under the category of ‘Anthelmintic flukicide for veterinary use.

Uses

An anthelmintic (fasciola).

Definition

ChEBI: 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole is an aromatic ether.

Triclabendazole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Triclabendazole manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Triclabendazole 68786-66-3
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-24
Hebei Chuanghai Biotechnology Co., Ltd
Product
Triclabendazole 68786-66-3
Price
US $10.00/kg
Min. Order
1kg
Purity
99.5%
Supply Ability
100 TON
Release date
2024-10-24
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Triclabendazole 68786-66-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
2ton/month
Release date
2021-06-19

68786-66-3, TriclabendazoleRelated Search:

Triethanolamine Nitroxinil Oxyclozanide Diclofenac sodium Ribavirin Ketoconazole Tilmicosin phosphate Triclabendazole Triclabendazole sulfoxide 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE 5-Chloro-2-mercaptobenzimidazole 5-METHOXYBENZIMIDAZOLE 1,2,4-Trichlorobenzene 2-(METHYLTHIO)BENZIMIDAZOLE 5-METHOXY-2-(METHYLTHIO)BENZIMIDAZOLE 1H-Benzimidazol-5-ol 5-HYDROXY-2-MERCAPTO-BENZIMIDAZOLE 6-CHLORO-2-(METHYLTHIO)-1H-BENZO[D]IMIDAZOLE

  • FASINEX
  • CGA-89317
  • 6-CHLORO-5-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-BENZIMIDAZOLE
  • 5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-1H-BENZIMIDAZOLE
  • TRICLABENDAZOLE
  • 5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1h-benzimidazol
  • Tricalbendazole
  • 5-Chloro-6-(2,3-dichlorophenoxy)-2-methylthio-1H-benzimidazole, CGA-89317, Fasinex
  • 1H-Benzimidazole, 5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-
  • 5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-(METHYLTHIO)-1H-BENZIMIDAZOL(TRICLABENDAZOLE)
  • 6-Chloro-5-(2,3-dichlorophenoxy)-2-(Methylthio)-1H-benzo[d]iMidazole
  • 5-Chloro-6-(2,3-dichlorophenoxy)-2-MethylthiobenziMidazole
  • CGA-89317, Egaten
  • 5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)benzimidazole 6-Chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)benzimidazole
  • Triclabendazol
  • 1H-Benzimidazole, 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-
  • 5-Chloro-6 (2,3-Dichlorophenoxy)-2- Methylthio-1H- Bezimidazole
  • Triclabendazole for system suitability
  • 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole
  • snalvbendaz
  • Triclabendazole Standard
  • Triclabendazole CRS
  • Triclabendazole for system suitability CRS
  • 6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzoimidazole
  • Triclabendazole USP/EP/BP
  • Triclabendazole (CGA89317)
  • Triclabendazole (Y0001737)
  • Triclabendazole EP
  • Triclabendazole API
  • Trichlorobenzimidazole
  • Triclabendazole (25 mg)
  • Triclabendazole in Methanol
  • C17795000 Triclabendazole
  • Triclabendazole 100 μg/ml Acetonitrile
  • Triclabendazole, 10 mM in DMSO
  • 68786-66-3
  • 68788-66-3
  • 68766-86-3
  • 168786-66-3
  • C14H19Cl3N2OS
  • C14H9Cl3N2OS
  • Veterinary drugs
  • APIs
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API's
  • Pharmaceutical intermediate
  • 68786-66-3