2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

Description

Product Name: 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
CAS No.: 37052-78-1
Chemical Name: 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
Synonyms: 5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL;Omeprazole Impurity A;OMeprazole Related CoMpound B;5-METHOXY-2-BENZIMIDAZOLETHIOL;5-METHOXY-2-MERCAPTOBENZIMIDAZOLE;5-methoxy-1H-benzoimidazole-2-thiol;H 118/87;5-Methoxy;OMEP IM-A;TIMTEC-BB SBB000219
CBNumber: CB9313620
Molecular Formula: C8H8N2OS
Formula Weight: 180.23
MOL File: 37052-78-1.mol

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2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Property

Melting point:: 261-263 °C(lit.)
Boiling point:: 309.4±44.0 °C(Predicted)
Density: 1.2425 (rough estimate)
vapor pressure: 0.001Pa at 25℃
refractive index: 1.5690 (estimate)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Sparingly)
form: Powder
pka: 10.13±0.30(Predicted)
color: Off-white to light yellow-brown
Water Solubility: insoluble
Sensitive: Air Sensitive
BRN: 3605123
InChI: 1S/C8H8N2OS/c1-11-5-2-3-6-7(4-5)10-8(12)9-6/h2-4H,1H3,(H2,9,10,12)
InChIKey: KOFBRZWVWJCLGM-UHFFFAOYSA-N
SMILES: COc1ccc2[nH]c(S)nc2c1
LogP: 1.52-2.399
CAS DataBase Reference: 37052-78-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-37-22
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29332900
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral
Aquatic Chronic 3
Skin Sens. 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 382485
Product name: 5-Methoxy-2-benzimidazolethiol
Purity: 99%
Packaging: 5g
Price: $54.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1478480
Product name: Omeprazole Related Compound B
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15mg
Price: $1200
Updated: 2025/07/31

TCI Chemical

Product number: M1256
Product name: 2-Mercapto-5-methoxybenzimidazole
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $81
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHR1986
Product name: Omeprazole RCB (USP)
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 30mg
Price: $623
Updated: 2025/07/31

TRC

Product number: M262760
Product name: 5-Methoxy-2-mercaptobenzimidazole
Packaging: 50g
Price: $305
Updated: 2021/12/16

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2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Chemical Properties,Usage,Production

Description

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfonyl]-1H-benzimidazole, 5-methoxy-2[[(4-methoxy-3, 5-dimethylpyridin-2-yl-1-oxide) methyl] sulfonyl]-1H-benzimidazole as well as tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate. Furthermore, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole1. Finally, it acts as an intermediate for manufacture of the anti-ulcer drug Omeprazole.

Chemical Properties

off-white to light yellowish-brown powder

Uses

Reagent used in the synthesis of COX-2 inhibitors

Uses

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.

Uses

5-Methoxy-2-benzimidazolethiol may be used in the preparation of compounds present as contaminants in omeprazole, such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. It may be used in the synthesis of tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ²P:P′;1:3κ²P:P′;2:3κ²P:P′-di-μ-bromido-1:2κ⁴Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Flammability and Explosibility

Not classified

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

Ufiprazole Omeprazole

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2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Suppliers

Americas 1 Belgium 3 Canada 7 China 552 Czech Republic 1 Europe 5 France 3 Germany 6 India 106 Japan 7 Slovakia 1 South Korea 2 Sweden 2 Switzerland 5 Ukraine 1 United Kingdom 15 United States 54 Global 771

Hunan Eurasian Pharmaceutical Co. Ltd.

Tel: 0592-5789919 13328776692
Email: 2851802018@qq.com;2851802016@qq.com
Country: China
ProdList: 79
Advantage: 58

Jinan Dexinjia Bio&Tech Co., Ltd

Tel: 0531-82375878 15865278590
Fax: 0531-82375893
Email: daisy@jndxj.com
Country: China
ProdList: 1634
Advantage: 58

Suzhou ARTK Medchem Co., Ltd.

Tel: 18168183658
Email: sales1@artkmedchem.com
Country: China
ProdList: 744
Advantage: 58

Xiamen keerda Biotechnology Co., Ltd

Tel: 0592-5639388; 18060983084
Email: 753760940@qq.com
Country: China
ProdList: 132
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Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd

Tel: 18317105404
Email: marketing002@witofly.com
Country: China
ProdList: 904
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

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View Lastest Price from 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-methyoxy-2-mercapto Benzimidazole 37052-78-1
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 97%-102%
Supply Ability: 10 tons
Release date: 2021-08-09

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE 37052-78-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-29

HebeiShuoshengImportandExportco.,Ltd

Product: 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE 37052-78-1
Price: US $6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000KG/Month
Release date: 2024-08-08

37052-78-1, 2-MERCAPTO-5-METHOXYBENZIMIDAZOLERelated Search:

2-Ethylhexyl mercaptoacetate Mercaptoacetic acid 2-Mercaptobenzimidazole 2-Methoxyethanol Benzimidazole 2-Methylbenzimidazole 3-Mercaptopropionic acid Ufiprazole OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS) Calcium thioglycolate Omeprazole 5-METHOXY-2-[((4-METHOXY-3,5-DIMETHYL-1-OXIDO-2-PYRIDINYL)METHYL)SULFINYL]-BENZIMIDAZOLE Esomeprazole Impurity 3 (S)-4-Desmethoxy-4-chloro Omeprazole 4-Hydroxy Omeprazole Omeprazole EP Impurity F Omeprazole Sulfone N-Oxide EsoMeprazole related substance H431/41

5-Methoxye-2-mercaplobenzinidazole

TIMTEC-BB SBB000219

5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL

5-Methoxybenzimidazole-2-thiol

5-METHOXY-2-THIOBENZIMIDAZOLE

5-METHOXY-2-MERCAPTOBENZIMIDAZOLE

5-METHOXY-2-BENZIMIDAZOLETHIOL

2-MERCAPTO-5-METHOXY-1H-BENZIMIDAZOLE

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

1,3-DIHYDRO-5-METHOXY-2H-BENZIMIDAZOLE-2-THIONE

LABOTEST-BB LT01596137

2-Mercapoto-5-Methoxy-1H-benzimidazole

Esomeprazole Sodium Impurity Ⅴ:5-Methoxy-2-mercaptobenzimidazole

5-Methoxy

H 118/87

5-methoxy-2(1H)-benzimidazolinethione

2-Mercato-5-methoxy benzimidazole

5-METHOXY-2-THIOHYDROXYBENZIMIDAZOLE(INTERMEDIATE OF OMEPRAZOLE)

2-Mercapto-5-MethoxyBenzimidazole(ForOmeprazole)

5-METHOXY-2-BENZIMIDAZOLEETHIOL

2-Mercapto-5-methoxy-1H-benzim

5-methoxy-2-thiohydroxy benzimidazole

5-Methoxy-2-thiobenzimidazole 99%

2H-Benzimidazole-2-thione,1,3-dihydro-5-methoxy-(9CI)

5-methoxy-1H-benzoimidazole-2-thiol

5-METHOXY-2-MERCAPTOBENIMIDAZOLEOMEPRAZOLE

5-METHOXYL-2-MERCAPTOBENZIMIDAZOLE

5-Methoxy-1H-1,3-benzodiazole-2-thiol

5-Methoxy-1,3-dihydrobenzimidazole-2-thione

5-Methoxy-2-benzimidazolethiol ,99%

5-METHOXY-2-MERCAPTOBENZIMIDAZOLE, 99+%

6-Methoxy-1H-benzimidazole-2-thiol

6-Methoxy-2-mercapto-1H-benzimidazole

5-Methoxy-2-mercapto

5-Methoxy-1H-benzimidazole-2-thiol 99%

(S)-Omeprazole Intermediate 2

5-Methoxy-2-thio-1H-benzimidazole

Omeprazole EP impurity-A (USP RC B)

Esomeprazole impurity A

Omeprazole Imp. A(EP)(USP RC B): (5-Methoxy-1H-Benzimidazole-2-Thiol)

2-mercapto-5-methyoxy benzimidazole (omeprazole-benzimidazole)

5-DIFLUOROMETHOXY-2-MERCAPTO- BENZIMIDZO LE

Omeprazole RCB (USP)

Esomeprazol EP Impurity A(Omeprazole EP Impurity A)

2-MERCAPTO -5-METHOXY BENZIMIDAZOLE (METOXITIONA )

OMEP IM-A

Omeprazole Impurity A

EsoMeprazole related substance A

EsoMeprazol iMpurity A

OMeprazole IMpurity-A (EP)

OMeprazole EP IMpurity A

5-Methoxy-1H-benzimidazole-2-thiol, 2-Mercapto-5-methoxy-1H-benzimidazole

5-Methoxy-2-thio-1H-benzimidazole 99%

5-Methoxy-1H-benzo[d]iMidazole-2(3H)-thione

OMeprazole IMpurity A (5-Methoxy-1H-BenziMidazole-2-Thiol)

5-Methoxy-1H-benzo[d]iMidazole-2-thiol (RelCpd A)

2H-BenziMidazole-2-thione, 1,3-dihydro-5-Methoxy-

2-Mercatto-5-Methoxy-1H-BenziMidazde