ChemicalBook > CAS DataBase List >  2-(4-Fluorophenyl)-thiophene

2-(4-Fluorophenyl)-thiophene

Product Name
2-(4-Fluorophenyl)-thiophene
CAS No.
58861-48-6
Chemical Name
2-(4-Fluorophenyl)-thiophene
Synonyms
2-(4-FL;AKOS BAR-1344;Canagliflozin INT2;IFLAB-BB F2108-0130;Impurity of caglitazin;FLUOROPHENYL)THIOPHENE;Cagliflozin Impurity 14;2-(4-Fluorphenyl)thiophen;Capagliflozin impurity 57;2-(4-fluorophenyl)thiophen
CBNumber
CB1294813
Molecular Formula
C10H7FS
Formula Weight
178.23
MOL File
58861-48-6.mol
More
Less

2-(4-Fluorophenyl)-thiophene Property

Melting point:
51.0 to 55.0 °C
Boiling point:
252.3±15.0 °C(Predicted)
Density 
1.200±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
soluble in Methanol
form 
powder to crystal
color 
Light orange to Yellow to Green
InChI
InChI=1S/C10H7FS/c11-9-5-3-8(4-6-9)10-2-1-7-12-10/h1-7H
InChIKey
PURJRGMZIKXDMW-UHFFFAOYSA-N
SMILES
C1(C2=CC=C(F)C=C2)SC=CC=1
CAS DataBase Reference
58861-48-6
More
Less

Safety

HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
F0724
Product name
2-(4-Fluorophenyl)thiophene
Purity
>95.0%(GC)
Packaging
1g
Price
$50
Updated
2024/03/01
TCI Chemical
Product number
F0724
Product name
2-(4-Fluorophenyl)thiophene
Purity
>95.0%(GC)
Packaging
5g
Price
$153
Updated
2024/03/01
TRC
Product number
F591560
Product name
2-(4-Fluorophenyl)-thiophene
Packaging
5g
Price
$1295
Updated
2021/12/16
ChemScene
Product number
CS-M2131
Product name
2-(4-Fluorophenyl)thiophene
Packaging
25g
Price
$50
Updated
2021/12/16
AK Scientific
Product number
W7182
Product name
2-(4-Fluorophenyl)thiophene
Packaging
5g
Price
$87
Updated
2021/12/16
More
Less

2-(4-Fluorophenyl)-thiophene Chemical Properties,Usage,Production

Chemical Properties

white solid

Uses

2-(4-Fluorophenyl)-thiophene can be used to prepare Canagliflozin (C175190) as sodium-dependent glucose co-transporter 2 (SGLT2) inhibitor for treatment of type 2 diabetes mellitus.

Synthesis

4-fluorobenzoic boric acid and 2-bromothiophene, Pd catalyst are added in organic solvent and dissolves, obtain material 3, wherein: 4-fluorine Phenylboric acid molar concentration in organic solvent is 0.5mol/L～2mol/L, and 4-fluorobenzoic boric acid with the mol ratio of 2-bromothiophene is 1:1.0～1:1.5,4-fluorobenzoic boric acid is 1:0.005～1:0.1 with the mol ratio of catalyst；Using material 3 with as material 4 Inorganic base aqueous solution carries out pre-incubation respectively to being 1:1.0～1 according to the mol ratio of 4-fluorobenzoic boric acid Yu alkali after reaction temperature: The mode of 3.0 mixes, and reacts under conditions of 50 ℃～80 ℃, then carries out post processing and obtains 2-(4-fluorophenyl) Thiophene.

2-(4-Fluorophenyl)-thiophene Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-(4-Fluorophenyl)-thiophene Suppliers

Americas 1 Canada 1 China 300 Europe 3 France 1 Germany 3 India 31 Japan 1 Russia 1 Slovakia 1 Switzerland 2 United Kingdom 4 United States 20 Global 369
Cangzhou Senary Chemical Science-tech Co., Ltd.
Tel
0317-5482966 17732392080
Fax
0317-5489300
Email
trade@senary.com
Country
China
ProdList
56
Advantage
58
Jiangsu laurel Pharma Co., Ltd
Tel
0517-83966898 15861782979
Email
32860091@qq.com
Country
China
ProdList
294
Advantage
58
Inner Mongolia Slanke Pharm-Tech Co., Ltd
Tel
0479-2224266; 15047962002
Email
1304140798@qq.com
Country
China
ProdList
73
Advantage
58
Hebei Maison Chemical Co.,Ltd.
Tel
0311-85381176 15511852758
Fax
0311-83832777
Email
ruby@maisonchem.com.cn
Country
China
ProdList
549
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44700
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12439
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9423
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14104
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11657
Advantage
64
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
21-31038972 15721252604
Fax
+86-21-51385350
Email
ammyzuo@harvest-chem.com
Country
China
ProdList
2540
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42959
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8846
Advantage
52
China Langchem Inc.
Tel
021-58956006 15800617331
Fax
021-58956100
Email
sales4@langchem.com
Country
China
ProdList
199
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4554
Advantage
62
Shanghai Sphchem Co., Ltd.
Tel
21-21-56491756 13512199871
Fax
021-5649-1756
Email
sales@panhongchem.com
Country
China
ProdList
4001
Advantage
55
Jinan Bond Chemical Technology Co., Ltd.
Tel
86-531-88280989
Fax
86-531-88280989
Email
mymail1996@126.com
Country
China
ProdList
258
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.
Tel
022-60116533 13207668525
Fax
022-60979672
Email
saleskc@scipharmacn.com
Country
China
ProdList
688
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9465
Advantage
58
SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.
Tel
021-34666753 13311639313
Fax
+86-21-34979012
Email
info@shyrchem.com
Country
China
ProdList
571
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25009
Advantage
65
Wuhan Kaymke Chemical Co., Ltd.,
Tel
027-027-87342388 18086026008
Fax
027-87342388
Email
sales@kaymke.com
Country
China
ProdList
3930
Advantage
55
China Nobel Chem Co., Limited
Tel
+86(0)21 60484900
Fax
+86(0)21 60484900
Country
China
ProdList
764
Advantage
50
Hunan Furui Biopharma Technology Co., Ltd.
Tel
15902102743
Fax
0731-57805668
Email
shelley@furuipharma.com
Country
China
ProdList
452
Advantage
55
Cangzhou Senary Chemical Science-tech Co., Ltd
Tel
+86-317-3563899
Fax
+86-317-3563199
Email
trade@senary.com
Country
China
ProdList
98
Advantage
56
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Fax
0086-0543-2240079
Email
zpmxchemical@126.com
Country
China
ProdList
1999
Advantage
62
ShangHai YingYi Chemical Technology Co., Ltd.
Tel
86-21-50700185 13764109623
Fax
86-21-50700185
Email
sale@inyelchem.com
Country
China
ProdList
178
Advantage
55
ALPENGLOW CHEMICAL INDUSTRIAL CO., LTD
Tel
086-0531-86986713
Fax
086-0531-86980810
Email
aplgroup@163.com
Country
China
ProdList
96
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41463
Advantage
60
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
1352-6885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
Country
China
ProdList
3991
Advantage
58
Chongqing Carechem Co.,Ltd.
Tel
18680818008/15802381793
Fax
086-23-86109835
Email
cqudgh@126.com
Country
China
ProdList
57
Advantage
58
Shanghai GaoLang Chemical Technology Co., Ltd.
Tel
021-57340939 18017297327
Fax
021-37210791
Email
sales@gaolangchemical.com
Country
China
ProdList
892
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18021
Advantage
56
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5876
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Hydragon Pharma Ltd
Tel
021-50215258
Fax
021-50215756
Email
market@hypharma.com
Country
China
ProdList
321
Advantage
58
Shanghai QianJin Chemical Technology Co., Ltd
Tel
021-20900665 17321230821
Fax
021-20900665
Email
2986274987@qq.com
Country
China
ProdList
923
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11369
Advantage
59
Lihe Wuhan New Chemical Materials Co., Ltd.
Tel
027-88395709
Fax
027-88391805
Country
China
ProdList
430
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16687
Advantage
50
Sicemo Ltd.
Tel
0532-85625977 13668866880
Email
interchem@foxmail.com
Country
China
ProdList
74
Advantage
55
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12357
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9957
Advantage
58
More
Less

View Lastest Price from 2-(4-Fluorophenyl)-thiophene manufacturers

Nanjing Fred Technology Co., Ltd
Product
2-(p-Fluorophenyl)thiophene 58861-48-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2024-01-02
Hebei Yanxi Chemical Co., Ltd.
Product
2-(4-FLUOROPHENYL)THIOPHENE 58861-48-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2023-09-15
Hebei Guanlang Biotechnology Co., Ltd.
Product
2-(4-FLUOROPHENYL)THIOPHENE 58861-48-6
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2021-11-11

58861-48-6, 2-(4-Fluorophenyl)-thiopheneRelated Search:

3-AMINO-2-CYANO-5-(4-FLUOROPHENYL)THIOPHENE,3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBONITRILE METHYL 3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXYLATE DUP-697 Ethyl 2-amino-4-(4-fluorophenyl)thiophene-3-carboxylate ,98% 3-AMINO-2-CYANO-5-(4-FLUOROPHENYL)THIOPHENE,3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBONITRILE 3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXAMIDE 5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXYLI& 6-(4-FLUOROPHENYL)-3,4-DIHYDROTHIENO[3,2-D]-PYRIMIDIN-4-ONE METHYL 5-(4-FLUOROPHENYL)-2-THIOPHENECARBOXYLATE 4-CHLORO-6-(4-FLUOROPHENYL)THIENO[3,2-D]PYRIMIDINE Methyl 2-[(chloroacetyl)amino]-4-(4-fluorophenyl)-thiophene-3-carboxylate 2-Amino-N-(2-fluorophenyl)thiophene-3-carboxamide Isopropyl 2-amino-4-(4-fluorophenyl)thiophene-3-carboxylate N-(5-amino-2-fluorophenyl)thiophene-2-sulfonamide 5-(3-fluorophenyl)thiophene-2-carboxylic acid methyl 2-[(cyanoacetyl)amino]-4-(4-fluorophenyl)thiophene-3-carboxylate ethyl 2-amino-4-(3-fluorophenyl)thiophene-3-carboxylate N-(3-amino-4-fluorophenyl)thiophene-2-carboxamide

  • IFLAB-BB F2108-0130
  • 2-(4-FLUOROPHENYL)THIOPHENE
  • AKOS BAR-1344
  • Thiophene, 2-(4-fluorophenyl)-
  • Canagliflozin intermediate
  • Canagliflozin Intermediate I
  • Canagliflozin INT2
  • 2-(4-fluorophenyl)thiophen
  • Canagliflozin Related Impurity 14
  • Cagliflozin Impurity 14
  • 2-(4-Fluorophenyl)thiophene&gt
  • 2-(4-FL
  • Impurity of caglitazin
  • 2-(4-FLUOROPHENYL)THIOPHENE 58861-48-6
  • 2-(4-FLUOROPHENYL)THIOPHENE ISO 9001：2015 REACH
  • 2-(4-Fluorphenyl)thiophen
  • 2-(p-Fluorophenyl)thiophene
  • FLUOROPHENYL)THIOPHENE
  • Capagliflozin impurity 57
  • 58861-48-6
  • 58861-48-6