ChemicalBook > CAS DataBase List >  2-(4-Fluorophenyl)-thiophene

2-(4-Fluorophenyl)-thiophene

Product Name
2-(4-Fluorophenyl)-thiophene
CAS No.
58861-48-6
Chemical Name
2-(4-Fluorophenyl)-thiophene
Synonyms
2-(4-FL;AKOS BAR-1344;Canagliflozin INT2;IFLAB-BB F2108-0130;Impurity of caglitazin;FLUOROPHENYL)THIOPHENE;Cagliflozin Impurity 14;2-(4-Fluorphenyl)thiophen;Capagliflozin impurity 57;2-(4-fluorophenyl)thiophen
CBNumber
CB1294813
Molecular Formula
C10H7FS
Formula Weight
178.23
MOL File
58861-48-6.mol
More
Less

2-(4-Fluorophenyl)-thiophene Property

Melting point:
51.0 to 55.0 °C
Boiling point:
252.3±15.0 °C(Predicted)
Density 
1.200±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
soluble in Methanol
form 
powder to crystal
color 
Light orange to Yellow to Green
InChI
InChI=1S/C10H7FS/c11-9-5-3-8(4-6-9)10-2-1-7-12-10/h1-7H
InChIKey
PURJRGMZIKXDMW-UHFFFAOYSA-N
SMILES
C1(C2=CC=C(F)C=C2)SC=CC=1
CAS DataBase Reference
58861-48-6
More
Less

Safety

HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
F0724
Product name
2-(4-Fluorophenyl)thiophene
Purity
>95.0%(GC)
Packaging
1g
Price
$50
Updated
2024/03/01
TCI Chemical
Product number
F0724
Product name
2-(4-Fluorophenyl)thiophene
Purity
>95.0%(GC)
Packaging
5g
Price
$153
Updated
2024/03/01
TRC
Product number
F591560
Product name
2-(4-Fluorophenyl)-thiophene
Packaging
5g
Price
$1295
Updated
2021/12/16
Matrix Scientific
Product number
090403
Product name
2-(4-Fluorophenyl)thiophene
Purity
95+%
Packaging
5g
Price
$1418
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0010377
Product name
2-(4-FLUORO-PHENYL)-THIOPHENE
Purity
95.00%
Packaging
20G
Price
$1903
Updated
2021/12/16
More
Less

2-(4-Fluorophenyl)-thiophene Chemical Properties,Usage,Production

Chemical Properties

white solid

Uses

2-(4-Fluorophenyl)-thiophene can be used to prepare Canagliflozin (C175190) as sodium-dependent glucose co-transporter 2 (SGLT2) inhibitor for treatment of type 2 diabetes mellitus.

Synthesis

4-fluorobenzoic boric acid and 2-bromothiophene, Pd catalyst are added in organic solvent and dissolves, obtain material 3, wherein: 4-fluorine Phenylboric acid molar concentration in organic solvent is 0.5mol/L～2mol/L, and 4-fluorobenzoic boric acid with the mol ratio of 2-bromothiophene is 1:1.0～1:1.5,4-fluorobenzoic boric acid is 1:0.005～1:0.1 with the mol ratio of catalyst；Using material 3 with as material 4 Inorganic base aqueous solution carries out pre-incubation respectively to being 1:1.0～1 according to the mol ratio of 4-fluorobenzoic boric acid Yu alkali after reaction temperature: The mode of 3.0 mixes, and reacts under conditions of 50 ℃～80 ℃, then carries out post processing and obtains 2-(4-fluorophenyl) Thiophene.

2-(4-Fluorophenyl)-thiophene Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-(4-Fluorophenyl)-thiophene Suppliers

Americas 1 Canada 1 China 304 Europe 3 France 1 Germany 3 India 31 Japan 1 Russia 1 Slovakia 1 Switzerland 2 United Kingdom 4 United States 20 Global 373
Cangzhou Senary Chemical Science-tech Co., Ltd.
Tel
0317-5482966 17732392080
Fax
0317-5489300
Email
trade@senary.com
Country
China
ProdList
56
Advantage
58
Jiangsu laurel Pharma Co., Ltd
Tel
15861782979
Email
32860091@qq.com
Country
China
ProdList
294
Advantage
58
Inner Mongolia Slanke Pharm-Tech Co., Ltd
Tel
0479-2224266; 15047962002
Email
1304140798@qq.com
Country
China
ProdList
73
Advantage
58
Hebei Maison Chemical Co.,Ltd.
Tel
0311-85381176 15511852758
Fax
0311-83832777
Email
ruby@maisonchem.com.cn
Country
China
ProdList
545
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
More
Less

View Lastest Price from 2-(4-Fluorophenyl)-thiophene manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2-(4-FLUOROPHENYL)THIOPHENE 58861-48-6
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-12-03
Nanjing Fred Technology Co., Ltd
Product
2-(p-Fluorophenyl)thiophene 58861-48-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2024-01-02
Hebei Yanxi Chemical Co., Ltd.
Product
2-(4-FLUOROPHENYL)THIOPHENE 58861-48-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2023-09-15

58861-48-6, 2-(4-Fluorophenyl)-thiopheneRelated Search:

3-AMINO-2-CYANO-5-(4-FLUOROPHENYL)THIOPHENE,3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBONITRILE METHYL 3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXYLATE DUP-697 Ethyl 2-amino-4-(4-fluorophenyl)thiophene-3-carboxylate ,98% 3-AMINO-2-CYANO-5-(4-FLUOROPHENYL)THIOPHENE,3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBONITRILE 3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXAMIDE 5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXYLI& 6-(4-FLUOROPHENYL)-3,4-DIHYDROTHIENO[3,2-D]-PYRIMIDIN-4-ONE METHYL 5-(4-FLUOROPHENYL)-2-THIOPHENECARBOXYLATE 4-CHLORO-6-(4-FLUOROPHENYL)THIENO[3,2-D]PYRIMIDINE Methyl 2-[(chloroacetyl)amino]-4-(4-fluorophenyl)-thiophene-3-carboxylate 2-Amino-N-(2-fluorophenyl)thiophene-3-carboxamide Isopropyl 2-amino-4-(4-fluorophenyl)thiophene-3-carboxylate N-(5-amino-2-fluorophenyl)thiophene-2-sulfonamide 5-(3-fluorophenyl)thiophene-2-carboxylic acid methyl 2-[(cyanoacetyl)amino]-4-(4-fluorophenyl)thiophene-3-carboxylate ethyl 2-amino-4-(3-fluorophenyl)thiophene-3-carboxylate N-(3-amino-4-fluorophenyl)thiophene-2-carboxamide

  • IFLAB-BB F2108-0130
  • 2-(4-FLUOROPHENYL)THIOPHENE
  • AKOS BAR-1344
  • Thiophene, 2-(4-fluorophenyl)-
  • Canagliflozin intermediate
  • Canagliflozin Intermediate I
  • Canagliflozin INT2
  • 2-(4-fluorophenyl)thiophen
  • Canagliflozin Related Impurity 14
  • Cagliflozin Impurity 14
  • 2-(4-Fluorophenyl)thiophene&gt
  • 2-(4-FL
  • Impurity of caglitazin
  • 2-(4-FLUOROPHENYL)THIOPHENE 58861-48-6
  • 2-(4-FLUOROPHENYL)THIOPHENE ISO 9001：2015 REACH
  • 2-(4-Fluorphenyl)thiophen
  • 2-(p-Fluorophenyl)thiophene
  • FLUOROPHENYL)THIOPHENE
  • Capagliflozin impurity 57
  • 58861-48-6
  • 58861-48-6