ChemicalBook > CAS DataBase List > Hydroxypioglitazone

Hydroxypioglitazone

Product Name
Hydroxypioglitazone
CAS No.
146062-44-4
Chemical Name
Hydroxypioglitazone
Synonyms
Leriglitazone;HYDROXYPIOGLITAZONE;Hydroxypioglitazone M4;Pioglitazone Impurity 4;Pioglitazone Impurity 18;Pioglitazone M4 Metabolite;Pioglitazone, hydroxy M-IV;Hydroxy Pioglitazone (M-IV) ;Hydroxy Pioglitazone Solution, 100ppm;5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE
CBNumber
CB1299313
Molecular Formula
C19H20N2O4S
Formula Weight
372.44
MOL File
146062-44-4.mol
More
Less

Hydroxypioglitazone Property

Melting point:
157-1580C
Boiling point:
627.6±55.0 °C(Predicted)
Density 
1.325±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
pka
6.35±0.50(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
CAS DataBase Reference
146062-44-4
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
28043
Product name
Hydroxy Pioglitazone
Packaging
1mg
Price
$275
Updated
2024/03/01
Cayman Chemical
Product number
28043
Product name
Hydroxy Pioglitazone
Packaging
5mg
Price
$820
Updated
2024/03/01
Usbiological
Product number
293691
Product name
Hydroxy pioglitazone
Packaging
1mg
Price
$827
Updated
2021/12/16
Usbiological
Product number
293692
Product name
Hydroxy pioglitazone
Packaging
1mg
Price
$891
Updated
2021/12/16
TRC
Product number
H952075
Product name
HydroxyPioglitazone(M-IV)
Packaging
10mg
Price
$1450
Updated
2021/12/16
More
Less

Hydroxypioglitazone Chemical Properties,Usage,Production

Description

Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor γ (PPARγ) agonist pioglitazone (Item Nos. 71745 | 22263 | 10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to PPARγ (Ki = 1.2 μM) and activates PPARγ in a time-resolved FRET (TR-FRET) assay (EC50 = 2.1 μM).

Chemical Properties

Off-White Solid

Uses

A metabolite of Pioglitazone (P471000).

Definition

ChEBI: Hydroxypioglitazone is a member of the class of thiazolidenediones that is the hydroxy derivative of pioglitazone. It has a role as a human xenobiotic metabolite. It is a member of thiazolidinediones, a member of pyridines and an aromatic ether. It is functionally related to a pioglitazone.

Hydroxypioglitazone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Hydroxypioglitazone Suppliers

Canada 4 China 48 France 1 Germany 1 India 5 United Kingdom 1 United States 16 Global 76
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
EJY Tech, Inc.
Tel
--
Fax
--
Country
United States
ProdList
448
Advantage
30
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Medical Isotopes
Tel
--
Fax
--
Email
stohler@medicalisotopes.com
Country
United States
ProdList
6181
Advantage
68
Syncom BV
Tel
--
Fax
--
Email
info@syncom.nl
Country
United States
ProdList
75
Advantage
0
Chemtos
Tel
--
Fax
--
Email
info@chemtos.com
Country
United States
ProdList
98
Advantage
0
CacheSyn Inc.
Tel
--
Fax
--
Email
info@cachesyn.com
Country
United States
ProdList
695
Advantage
50
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
SynFine Research
Tel
--
Fax
--
Email
research@synfine.com
Country
United States
ProdList
1024
Advantage
68
More
Less

View Lastest Price from Hydroxypioglitazone manufacturers

Career Henan Chemical Co
Product
Hydroxypioglitazone 146062-44-4
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
100kg
Release date
2018-12-24

146062-44-4, HydroxypioglitazoneRelated Search:

Pioglitazone 4'-Hydroxyacetophenone Pioglitazone Troglitazone Gliquidone Pioglitazone hydrochloride a-[(Aminocarbonyl)thio]-4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzenepropanoic Acid Ethyl Ester Pioglitazone Aldehyde Impurity 5-(4-Fluorobenzyl)-2,4-thiazolidinedione 4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyaldehyde Hydroxy Pioglitazone (M-II) (Mixture of Diastereomers) Pioglitazone Sulfonic Acid IMpurity 2-[2-(4-BroMophenoxy)ethyl]-5-ethylpyridine Pioglitazone Impurity 5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidinone Pioglitazone N-Oxide 5-(4-Hydroxybenzyl)-2,4-thiazolidinedione 5-[[4-[2-(5-ACETYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYL]-2,4THIAZOLIDINEDIONE

  • HYDROXYPIOGLITAZONE
  • Hydroxy Pioglitazone (M-IV)
  • 5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE
  • Pioglitazone, hydroxy M-IV
  • Pioglitazone Impurity 18
  • Hydroxy Pioglitazone Solution, 100ppm
  • Pioglitazone M4 Metabolite
  • Leriglitazone
  • Pioglitazone Impurity 4
  • 2,4-Thiazolidinedione, 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-
  • Hydroxypioglitazone M4
  • 146062-44-4
  • Sulfur & Selenium Compounds
  • Various Metabolites and Impurities
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals