3-CARBETHOXYUMBELIFERONE

Product Name: 3-CARBETHOXYUMBELIFERONE
CAS No.: 6093-71-6
Chemical Name: 3-CARBETHOXYUMBELIFERONE
Synonyms: YZ9;AURORA 9226;AKOS BBS-00008132;YZ9, 10 mM in DMSO;YZ9, PFKFB3 inhibitor;3-CARBETHOXYUMBELIFERONE;ETHYL 3-UMBELLIFERYLCARBOXYLATE;ethyl umbelliferone-3-carboxylate;Ethyl 7-Hydroxycoumarin-3-carboxylate;Ethyl7-Hydroxycoumarin-3-carboxylate>
CBNumber: CB1302710
Molecular Formula: C12H10O5
Formula Weight: 234.2
MOL File: 6093-71-6.mol

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3-CARBETHOXYUMBELIFERONE Property

Melting point:: 170.0 to 174.0 °C
Boiling point:: 448.3±45.0 °C(Predicted)
Density: 1.397±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO: soluble5mg/mL, clear (warmed)
pka: 7.32±0.20(Predicted)
form: powder
color: white to beige
λmax: 398nm(EtOH)(lit.)
CAS DataBase Reference: 6093-71-6

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Safety

WGK Germany: 3
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1270
Product name: 7-Hydroxycoumarin-3-carboxylic acid ethyl ester
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $94.3
Updated: 2024/03/01

TCI Chemical

Product number: E1017
Product name: Ethyl 7-Hydroxycoumarin-3-carboxylate
Purity: >98.0%(GC)
Packaging: 200mg
Price: $174
Updated: 2024/03/01

Cayman Chemical

Product number: 15352
Product name: YZ9
Purity: ≥98%
Packaging: 5mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 15352
Product name: YZ9
Purity: ≥98%
Packaging: 10mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 15352
Product name: YZ9
Purity: ≥98%
Packaging: 50mg
Price: $139
Updated: 2024/03/01

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3-CARBETHOXYUMBELIFERONE Chemical Properties,Usage,Production

Chemical Properties

Brown solid

Uses

Z9 is a potent inhibitor of PFKFB3, a member of 6-phosphofructo-2-kinases family. It avidly competes with fructose 6-phosphate (F6P) at PFKFB3. YZ9 is also cell permeable, inhibiting the growth of HeLa cells.

Biological Activity

YZ9 is a 5, 6, 7, 8-tetrahydroxy-2-(4-hydroxyphenyl) chromen-4-one (N4A) inhibitor.', 'YZ9 is a potent inhibitor of PFKFB3 (6-phosphfructo-2-kinase/fructose-2,6-bisphosphatase) with an IC50 = 183 nM. PFKFB3 is over expressed in many cancers and catalyzes the production of fructose-2,6-bisphosphate, which can potentiate PFK1 activity, enhancing glycolysis in tumor cells. YZ9 dose dependently inhibits proliferation of HeLa cells.

3-CARBETHOXYUMBELIFERONE Preparation Products And Raw materials

Raw materials

2,4-Dihydroxybenzaldehyde Ethyl acetate Diethyl malonate PETROLEUM ETHER

Preparation Products

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3-CARBETHOXYUMBELIFERONE Suppliers

Americas 1 Austria 1 China 76 Europe 1 Germany 1 India 2 Japan 1 Switzerland 1 United Kingdom 4 United States 13 USA 1 Global 102

Aurora Fine Chemicals Ltd.

Tel: --
Fax: --
Email: aurora@aurorafinechemicals.com
Country: Austria
ProdList: 6625
Advantage: 72

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View Lastest Price from 3-CARBETHOXYUMBELIFERONE manufacturers

Dideu Industries Group Limited

Product: 3-CARBETHOXYUMBELIFERONE 6093-71-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-11-01

Career Henan Chemical Co

Product: 3-CARBETHOXYUMBELIFERONE 6093-71-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: KG/T
Release date: 2019-12-19

6093-71-6, 3-CARBETHOXYUMBELIFERONERelated Search:

4-HYDROXY MEPHENYTOIN 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID ETHYL COUMARIN-3-CARBOXYLATE Coumarin-3-carboxylic acid 7-Hydroxycoumarin 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID OCTADECYL ESTER AFLATOXIN G2A ETHYL 7-ACETOXYCOUMARIN-3-CARBOXYLATE AFLATOXIN G2 AFLATOXIN G1 AURORA 20153 Aflatoxin AURORA 20138 AURORA 20139 3-CARBETHOXYUMBELIFERONE AURORA 22535

AURORA 9226

ETHYL 3-UMBELLIFERYLCARBOXYLATE

7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID ETHYL ESTER

AKOS BBS-00008132

3-CARBETHOXYUMBELIFERONE

UMBELLIFERONE 3-CARBOXYLIC ACID ETHYL ESTER

Ethyl 7-hydroxy-2-oxo-2H-chroMene-3-carboxylate

Ethyl 7-Hydroxycoumarin-3-carboxylate

3-CARBETHOXYUMBELIFERONE7-Hydroxy-2-oxo-2H-chromene-3-carboxylic acid ethyl ester

YZ9

ethyl 7-hydroxy-2-oxochromene-3-carboxylate

ethyl umbelliferone-3-carboxylate

7-Hydroxycoumarin-3-carboxylic acid ethyl ester ,98%

Ethyl 7-hydroxy-2-oxo-2H-1-benzopyran-3-carboxylate

Ethyl7-Hydroxycoumarin-3-carboxylate&gt

2H-1-Benzopyran-3-carboxylic acid, 7-hydroxy-2-oxo-, ethyl ester

3-CARBETHOXYUMBELIFERONE ISO 9001：2015 REACH

YZ9, PFKFB3 inhibitor

YZ9, 10 mM in DMSO

6093-71-6

Fluorogenic

Activity

Aromatic Esters