7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
- Product Name
- 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
- CAS No.
- 779-27-1
- Chemical Name
- 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
- Synonyms
- 7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID;RARECHEM AL BO 2319;OTAVA-BB BB7015592710;3-CARBOXY-7-HYDROXYCOUMARIN;7-hydroxy-3-carboxycoumarin;UMBELLIFERONE-3-CARBOXYLIC ACID;7-HYDROXYCOUMARIM-3-CARBOXYLIC ACID;7-Hydroxycoumarin-3-carboxylicAcid>7-Hydroxycoumarin-3-carboxylic acid ,98%;7-hydroxy-2-oxochromene-3-carboxylic acid
- CBNumber
- CB5496161
- Molecular Formula
- C10H6O5
- Formula Weight
- 206.15
- MOL File
- 779-27-1.mol
7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID Property
- Melting point:
- 261 °C(lit.)
- Boiling point:
- 474.8±45.0 °C(Predicted)
- Density
- 1.639±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- DMF: soluble
- pka
- 7.04 ± 0.02, temperature: 23 °C
- form
- powder to crystal
- color
- Yellow solid;Orange solid; Off-white powder
- λmax
- 386 nm (Buffer pH 10.0); 339 nm (Buffer pH 4.0)
- BRN
- 384141
- Major Application
- Carbon-dioxide sensor; chemical sensors based on non-linear optics; monitoring of cationic photopolymerization processes; nanomaterials
- Biological Applications
- Chemical dosimeter for radiation therapy; detecting bacteria; detecting/sensing hydroxyl radicals; studying nucleic acids; as a substrate for measuring carboxylesterases activity, cellulases activity, β-galactosidases activity, glycosidases activity, glycosyltransferases activity, hydrolases activity, 4-hydroxycinnamate decarboxylases activity, β-lactamases activity, phosphatases activity, sulfatases activity; treating cancer/antitumor activity
- InChI
- InChI=1S/C10H6O5/c11-6-2-1-5-3-7(9(12)13)10(14)15-8(5)4-6/h1-4,11H,(H,12,13)
- InChIKey
- LKLWLDOUZJEHDY-UHFFFAOYSA-N
- SMILES
- C1(=O)OC2=CC(O)=CC=C2C=C1C(O)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 55155
- Product name
- 7-Hydroxycoumarin-3-carboxylic acid
- Purity
- suitable for fluorescence, ≥98.0% (TLC)
- Packaging
- 100MG
- Price
- $298
- Updated
- 2025/07/31
- Product number
- H1352
- Product name
- 7-Hydroxycoumarin-3-carboxylic Acid
- Purity
- >98.0%(HPLC)
- Packaging
- 200mg
- Price
- $178
- Updated
- 2025/07/31
- Product number
- H1352
- Product name
- 7-Hydroxycoumarin-3-carboxylic Acid
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $616
- Updated
- 2025/07/31
- Product number
- H825168
- Product name
- 7-Hydroxycoumarin-3-carboxylic Acid
- Packaging
- 1g
- Price
- $265
- Updated
- 2021/12/16
- Product number
- FU66533
- Product name
- Umbelliferone-3-carboxylic acid
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID Chemical Properties,Usage,Production
Chemical Properties
Light yellow powder
Uses
7-Hydroxycoumarin-3-carboxylic acid is a pH-indicator that can be immobilized on a support to give a pH sensor.
Uses
Suitable as pH-indicator.
Synthesis
6093-71-6
779-27-1
General procedure for the synthesis of 7-hydroxy-2-oxo-2H-benzopyran-3-carboxylic acid from ethyl 7-hydroxy-2-oxo-2H-benzopyran-3-carboxylate: ethyl 7-hydroxy-2-oxo-2H-benzopyran-3-carboxylate (2.00 g, 8.55 mmol) was dissolved in water (20 ml) at 90 °C and concentrated hydrochloric acid (6 ml) was added slowly. The reaction mixture was refluxed for 8 hours. After the reaction was completed, the reaction solution was cooled to room temperature, the precipitate was collected by filtration and washed with cold water to obtain 7-hydroxy-2-oxo-2H-benzopyran-3-carboxylic acid (1.32 g, 6.41 mmol) as a light red solid in 75% yield.
References
[1] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986, vol. 25, p. 638 - 639
[2] Food Chemistry, 2012, vol. 135, # 4, p. 2872 - 2878
[3] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 5, p. 502 - 506
[4] Chemical Communications, 2017, vol. 53, # 11, p. 1813 - 1816
[5] Patent: CN106279125, 2017, A. Location in patent: Paragraph 0041; 0042
7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID manufacturers
- Product
- 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID 779-27-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-29
- Product
- 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID 779-27-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID 779-27-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09