ChemicalBook > CAS DataBase List > Ethopabate

Ethopabate

Product Name
Ethopabate
CAS No.
59-06-3
Chemical Name
Ethopabate
Synonyms
METHYL 4-ACETAMIDO-2-ETHOXYBENZOATE;4-Acetamido-2-ethoxybenzoic acid, methyl ester;ETHOPABATE;Ethopatate;Ethytpatate;Ethyl pabate;Isovaleraldehvde;Ethopabate (125 mg);Ethopabate, Vetranal;Ethopabate (1262801)
CBNumber
CB1307306
Molecular Formula
C12H15NO4
Formula Weight
237.25
MOL File
59-06-3.mol
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Ethopabate Property

Melting point:
148-151 °C
Boiling point:
426.1±35.0 °C(Predicted)
Density 
1.180±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO: 50 mg/mL (210.75 mM)
form 
A solid
pka
14.12±0.70(Predicted)
Merck 
13,3781
InChI
InChI=1S/C12H15NO4/c1-4-17-11-7-9(13-8(2)14)5-6-10(11)12(15)16-3/h5-7H,4H2,1-3H3,(H,13,14)
InChIKey
GOVWOKSKFSBNGD-UHFFFAOYSA-N
SMILES
C(OC)(=O)C1=CC=C(NC(C)=O)C=C1OCC
CAS DataBase Reference
59-06-3(CAS DataBase Reference)
EPA Substance Registry System
Ethopabate (59-06-3)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
HS Code 
2924296000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1262801
Product name
Ethopabate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
125mg
Price
$358
Updated
2024/03/01
Usbiological
Product number
011457
Product name
Ethopabate
Packaging
250mg
Price
$418
Updated
2021/12/16
TRC
Product number
E890800
Product name
Ethopabate
Packaging
250mg
Price
$145
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
APN0000389
Product name
METHYL-4-ACETAMIDO-2-ETHOXYBENZOATE
Purity
95.00%
Packaging
1G
Price
$329.7
Updated
2021/12/16
AK Scientific
Product number
D383
Product name
Ethopabate
Packaging
100mg
Price
$49
Updated
2021/12/16
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Ethopabate Chemical Properties,Usage,Production

Description

Ethopabate is a veterinary drug belonging to the class of antibiotics which contains an arylamide with a phenyl ring, a monocyclic aromatic hydrocarbon, and is a very safe drug used for the prophylaxis and treatment of coccidiosis in chickens. It has anticoccidial activity, especially against the intestinal form, and lacks activity against E. tenella of the cecum worm. The drug is a competitor of PABA, which is absorbed by the parasite and interferes with folate synthesis. It has good activity against E. acervulina and some strains of E. maxima and E. brunette. It is used only in combination with amprolium, first at a concentration of 4 ppm and later at a concentration of 40 ppm.This drug reaches peak activity on day 4 of the cycle.

Chemical Properties

White to Off-White Solid

Uses

A supplementary drug that improves the coccidiostatic effect of nicarbazin and amprolium in order to cure coccidiosis in chickens.

Uses

antidepressant

Definition

ChEBI: Ethopabate is an amidobenzoic acid.

Clinical Use

Ethopabate is only a narrow anticoccidial spectrum drug against Eimeria acervulina. It has no or only slight activity against E. maxima, E. necatrix, E. tenella or E. brunetti. Today, ethopabate is applied only in combination with amprolium and sulfonamide.

Molecular Interactions

Ethopabate is a 2-substituted PABA derivative (=4-acetamido-2-ethoxybenzoic acid methylester) and functions as a prodrug. Its activity becomes potentiated by pyrimethamine and antagonised by the simultaneous administration of PABA. Thus, the mode of action of ethopabate is similar to that of sulfonamides or sulfones.

Ethopabate Preparation Products And Raw materials

Raw materials

3-Methyl-1-butanol

Preparation Products

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Ethopabate Suppliers

Canada 2 China 242 Europe 1 Germany 2 India 16 Japan 2 Switzerland 1 United Kingdom 7 United States 21 Global 295
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View Lastest Price from Ethopabate manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Ethopabate 59-06-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-04-10
shandong perfect biotechnology co.ltd
Product
Ethopabate 59-06-3
Price
US $0.00/kg
Min. Order
1kg
Purity
98% HPLC
Supply Ability
100kg
Release date
2023-07-19
Hebei Duling International Trade Co. LTD
Product
Ethopabate 59-06-3
Price
US $100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2023-05-30

59-06-3, EthopabateRelated Search:

Methyl acrylate N-Acetylsulfanilyl chloride Thiophanate-methyl Acetaminophen Methylparaben Methyl 2-bromobenzoate 4-Acetylbenzoic acid Chlorantraniliprole Methyl benzoate Kresoxim-methyl Methyl 4-cyanobenzoate METHYL THIOPHENE-2-CARBOXYLATE Bensulfuron methyl Methyl acetate Pyrimethamine Methyl ar-ethoxybenzamide 4-Ethoxy-[1,1'-biphenyl]-4'-carbonitrile

  • Ethopabate, Vetranal
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  • 59-06-3
  • 1959-06-3
  • 1959/6/3
  • 21704
  • 59-60-3
  • C12H15O4N
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