ChemicalBook > CAS DataBase List > CC-885

CC-885

Product Name
CC-885
CAS No.
1010100-07-8
Chemical Name
CC-885
Synonyms
CC-885;CC-885, 10 mM in DMSO;Ligands for E3 Ligase,CC-885,CC 885,E3 ligase-recruiting Moiety,CC885,Inhibitor,inhibit;1-(3-Chloro-4-methylphenyl)-3-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)urea;Urea, N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-
CBNumber
CB13159377
Molecular Formula
C22H21ClN4O4
Formula Weight
440.88
MOL File
1010100-07-8.mol
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CC-885 Property

solubility 
DMSO:40.0(Max Conc. mg/mL);90.72(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.45(Max Conc. mM)
DMF:12.5(Max Conc. mg/mL);28.35(Max Conc. mM)
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19966
Product name
CC-885
Purity
≥98%
Packaging
500μg
Price
$90
Updated
2024/03/01
Cayman Chemical
Product number
19966
Product name
CC-885
Purity
≥98%
Packaging
1mg
Price
$171
Updated
2024/03/01
Cayman Chemical
Product number
19966
Product name
CC-885
Purity
≥98%
Packaging
5mg
Price
$578
Updated
2024/03/01
Cayman Chemical
Product number
19966
Product name
CC-885
Purity
≥98%
Packaging
10mg
Price
$886
Updated
2024/03/01
AK Scientific
Product number
1485DC
Product name
1-(3-Chloro-4-methylphenyl)-3-[[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]methyl]urea
Packaging
1mg
Price
$293
Updated
2021/12/16
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CC-885 Chemical Properties,Usage,Production

Description

CC-885 is a potent Cereblon Modulator with potent antitumor activity mediated through the degradation of GSPT1. was demonstrated to mediate antitumor effects through the recruitment and degradation of G1 to S phase transition 1 protein (GSPT1). GSPT1 (also named eRF3a) is a translation termination factor that binds eukaryotic translation termination factor 1 (eFR1) to mediate stop codon recognition and nascent protein release from the ribosome.

target

CC-885 is a cereblon (CRBN) modulator.

CC-885 Preparation Products And Raw materials

Raw materials

Preparation Products

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CC-885 Suppliers

China 65 United States 6 USA 1 Global 72
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1010100-07-8, CC-885Related Search:

CCT128930 CC-122 CCT 137690 CCG215022 CC-92480 3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-(2-furanyl)benzoyl]- CCT245737 CCF-642

  • CC-885
  • Urea, N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-
  • 1-(3-Chloro-4-methylphenyl)-3-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)urea
  • Ligands for E3 Ligase,CC-885,CC 885,E3 ligase-recruiting Moiety,CC885,Inhibitor,inhibit
  • CC-885, 10 mM in DMSO
  • 1010100-07-8