m-PEG11-acid

Product Name: m-PEG11-acid
CAS No.: 2280998-74-3
Chemical Name: m-PEG11-acid
Synonyms: mPEG10-PA;mPEG-NH2,5K;m-PEG11-acid;2,5,8,11,14,17,20,23,26,29,32-Undecaoxapentatriacontan-35-oic acid;mPEG10-CH2CH2COOH/2,5,8,11,14,17,20,23,26,29,32-undecaoxapentatriacontan-35-oic acid;3-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
CBNumber: CB13162997
Molecular Formula: C24H48O13
Formula Weight: 544.64
MOL File: 2280998-74-3.mol

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m-PEG11-acid Property

Boiling point:: 599.1±50.0 °C(Predicted)
Density: 1.113±0.06 g/cm3(Predicted)
solubility: DMSO : 100 mg/mL (183.61 mM; Need ultrasonic)
form: Liquid
pka: 4.28±0.10(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22093
Product name: m-PEG11-acid
Purity: 98%
Packaging: 1g
Price: $480
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1550
Product name: m-PEG11-acid
Packaging: 500mg
Price: $832
Updated: 2021/12/16

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m-PEG11-acid Chemical Properties,Usage,Production

Description

m-PEG11-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Biological Activity

M-PEG11-acid is a non-cleavable ADC linker containing 11-unit PEG, which can be used to synthesize antibody drug conjugates (ADC). m-PEG11-acid is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

PEGs	Non-cleavable

m-PEG11-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG11-acid Suppliers

China 38 United Kingdom 1 United States 4 Global 43

LAURENT.INC

Tel: 17721037897
Email: sun@laurentpeg.com
Country: China
ProdList: 490
Advantage: 58

Jinan elephant international trading co., LTD

Tel
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Email: 13006575422@163.com
Country: China
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
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Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28772
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Hangzhou HanLai Biochemical Technology Co., Ltd.

Tel: 571-86101219 18768477782
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Email: sales09@leobiochem.com
Country: China
ProdList: 433
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
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Alpha Biopharmaceuticals Co., Ltd

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Henan Alpha Chemical Co., Ltd.

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Email: 3957071458@qq.com
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Henan Alfa Chemical Co., Ltd

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Email: sale03@alfachem.cn
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

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View Lastest Price from m-PEG11-acid manufacturers

LAURENT

Product: mPEG10-CH2CH2COOH 2280998-74-3
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 500kg
Release date: 2026-01-28

Xian confluore Biological Technology Co., Ltd.

Product: m-PEG11-COOH 2280998-74-3
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-27

2280998-74-3, m-PEG11-acidRelated Search:

mPEG11-Br 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontanoic acid mPEG22-NH2 Methyl-PEG24-Amine m-PEG17-acid mPEG17-NH2 MPEG11-SH 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine MPEG7-CH2CH2COOH MPEG4-CH2CH2COOH Triethylene Glycol 2-Bromoethyl Methyl Ether m-PEG6-acid INDEX NAME NOT YET ASSIGNED 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70-Tricosaoxahenheptacontanoic acid azido-mPEG11 m-PEG11-CHO m-PEG11-Mal m-PEG11-Ph-CHO

m-PEG11-acid

mPEG10-CH2CH2COOH/2,5,8,11,14,17,20,23,26,29,32-undecaoxapentatriacontan-35-oic acid

3-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

2,5,8,11,14,17,20,23,26,29,32-Undecaoxapentatriacontan-35-oic acid

mPEG-NH2,5K

mPEG10-PA

2280998-74-3

C24H48O13