m-PEG3-Sulfone-PEG3-t-butyl ester

Product Name: m-PEG3-Sulfone-PEG3-t-butyl ester
CAS No.: 2055041-00-2
Chemical Name: m-PEG3-Sulfone-PEG3-t-butyl ester
Synonyms: m-PEG3-Sulfone-PEG3-Boc;m-PEG3-Sulfone-PEG3-t-butyl ester;4,7,10,16,19,22-Hexaoxa-13-thiatricosanoic acid, 1,1-dimethylethyl ester, 13,13-dioxide
CBNumber: CB13163015
Molecular Formula: C20H40O10S
Formula Weight: 472.59
MOL File: 2055041-00-2.mol

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m-PEG3-Sulfone-PEG3-t-butyl ester Property

Boiling point:: 565.2±50.0 °C(Predicted)
Density: 1.121±0.06 g/cm3(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23175
Product name: m-PEG3-Sulfone-PEG3-t-butylester
Purity: 96%
Packaging: 250mg
Price: $450
Updated: 2021/12/16

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m-PEG3-Sulfone-PEG3-t-butyl ester Chemical Properties,Usage,Production

Description

m-PEG3-Sulfone-PEG3-t-butyl ester is a PEG linker containing sulfone and t-butyl ester moieties. The sulfone can react with thiol groups of proteins. The t-butyl can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Uses

m-PEG3-Sulfone-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

m-PEG3-Sulfone-PEG3-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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m-PEG3-Sulfone-PEG3-t-butyl ester Suppliers

China 13 United States 3 Global 16

Xi'an Confluore Biological Technology Co., Ltd.

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View Lastest Price from m-PEG3-Sulfone-PEG3-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: m-PEG3-Sulfone-PEG3-t-butyl ester 2055041-00-2
Price: US $0.00/mg
Min. Order: 500mg
Purity: >95.00%
Supply Ability: 500mg
Release date: 2024-03-28

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m-PEG3-Sulfone-PEG3-t-butyl ester

m-PEG3-Sulfone-PEG3-Boc

4,7,10,16,19,22-Hexaoxa-13-thiatricosanoic acid, 1,1-dimethylethyl ester, 13,13-dioxide

2055041-00-2

C20H40O10S