Tos-PEG9-t-butyl ester
- Product Name
- Tos-PEG9-t-butyl ester
- CAS No.
- 1345337-28-1
- Chemical Name
- Tos-PEG9-t-butyl ester
- Synonyms
- Tos-PEG9-Boc;Tos-PEG8-CH2CH2COOtBu;Tos-PEG9-t-butyl ester;tert-butyl 1-(tosyloxy)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate;4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester;Tos-PEG8-CH2CH2COOtBu/4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB13167129
- Molecular Formula
- C30H52O13S
- Formula Weight
- 652.79
- MOL File
- 1345337-28-1.mol
Tos-PEG9-t-butyl ester Property
- Boiling point:
- 677.8±55.0 °C(Predicted)
- Density
- 1.142±0.06 g/cm3(Predicted)
- storage temp.
- Store at Room Tem.
- solubility
- Soluble in DMSO, DCM, DMF
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-23294
- Product name
- Tos-PEG9-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $540
- Updated
- 2021/12/16
- Product number
- B-1088
- Product name
- Tos-PEG8-CH2CH2COOtBu
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $183.34
- Updated
- 2021/12/16
- Product number
- P1081-00-N
- Product name
- tert-butyl1-(tosyloxy)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $348
- Updated
- 2021/12/16
Tos-PEG9-t-butyl ester Chemical Properties,Usage,Production
Description
Tos-PEG9-t-butyl ester is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
Uses
Tos-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6
Tos-PEG9-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Tos-PEG9-t-butyl ester manufacturers
- Product
- tert-butyl 1-(tosyloxy)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate 1345337-28-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-15
- Product
- Tos-PEG9-COOtBu 1345337-28-1
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >96.00%
- Supply Ability
- 1g
- Release date
- 2024-03-27