Tri(Ethylene Glycol) DI-P-Toluenesulfonate

Product Name: Tri(Ethylene Glycol) DI-P-Toluenesulfonate
CAS No.: 19249-03-7
Chemical Name: Tri(Ethylene Glycol) DI-P-Toluenesulfonate
Synonyms: (Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-Methylbenzenesulfonate);1,10-Ditosyl-1,4,7,10-tetraoxadecane;TRIETHYLENE GLYCOL DITOSYLATE;TRIETHYLENE GLYCOL BIS(P-TOLUENESULFONATE);Tos-PEG4-Tos;Tos-PEG3-Tos;Bis-Tos-PEG3;TSO-PEG3-OTS;CAS_19249-03-7;Trivinyl glycol
CBNumber: CB4227531
Molecular Formula: C20H26O8S2
Formula Weight: 458.55
MOL File: 19249-03-7.mol

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Tri(Ethylene Glycol) DI-P-Toluenesulfonate Property

Melting point:: 78-82 °C(lit.)
Boiling point:: 534.03°C (rough estimate)
Density: 1.3164 (rough estimate)
refractive index: 1.6000 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Soluble in ethanol.
form: powder to crystal
color: White to Almost white
BRN: 632509
InChI: InChI=1S/C20H26O8S2/c1-17-3-7-19(8-4-17)29(21,22)27-15-13-25-11-12-26-14-16-28-30(23,24)20-9-5-18(2)6-10-20/h3-10H,11-16H2,1-2H3
InChIKey: KCONMNWPRXAWKK-UHFFFAOYSA-N
SMILES: C(OCCOS(C1=CC=C(C)C=C1)(=O)=O)COCCOS(C1=CC=C(C)C=C1)(=O)=O
CAS DataBase Reference: 19249-03-7(CAS DataBase Reference)
EPA Substance Registry System: Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-, bis(4-methylbenzenesulfonate) (19249-03-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29093090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 339032
Product name: Triethylene glycol di(p-toluenesulfonate)
Purity: 98%
Packaging: 10g
Price: $56.5
Updated: 2025/07/31

TCI Chemical

Product number: T1488
Product name: Triethylene Glycol Bis(p-toluenesulfonate)
Purity: >97.0%(HPLC)
Packaging: 10g
Price: $76
Updated: 2025/07/31

TCI Chemical

Product number: T1488
Product name: Triethylene Glycol Bis(p-toluenesulfonate)
Purity: >97.0%(HPLC)
Packaging: 25g
Price: $130
Updated: 2025/07/31

TRC

Product number: E917743
Product name: (Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl)bis(4-Methylbenzenesulfonate)
Packaging: 50mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: J96812
Product name: Tri(ethylene glycol) di-p-toluenesulfonate
Packaging: 1g
Price: $10
Updated: 2021/12/16

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Tri(Ethylene Glycol) DI-P-Toluenesulfonate Chemical Properties,Usage,Production

Description

Tos-PEG4-Tos is a PEG linker containing two tosyl groups. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Chemical Properties

WHITE POWDER

Uses

Tri(ethylene glycol) di-p-toluenesulfonate is used in the synthesis of 1-[4-(1,4,7,10-tetraoxa-13-aza-cyclopentadec-13-yl)-phenyl] ethanone.

Synthesis

2,2'-[1,2-ethanediylbis(oxy)]bisethanol and p-toluenesulfonyl chloride can be used as raw materials for the synthesis of Tri(Ethylene Glycol) DI-P-Toluenesulfonate.

References

[1] Organic and Biomolecular Chemistry, 2006, vol. 4, # 11, p. 2082 - 2087
[2] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 14, p. 4841 - 4856
[3] Organic and Biomolecular Chemistry, 2015, vol. 13, # 30, p. 8335 - 8348
[4] Journal of Medicinal Chemistry, 2016, vol. 59, # 17, p. 7840 - 7855
[5] Journal of Organic Chemistry, 1992, vol. 57, # 24, p. 6678 - 6680

Tri(Ethylene Glycol) DI-P-Toluenesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

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Tri(Ethylene Glycol) DI-P-Toluenesulfonate Suppliers

Belgium 2 Canada 2 China 207 Germany 3 India 6 Japan 3 Switzerland 1 United Kingdom 7 United States 19 Global 250

Suzhou Highfine Biotech Co., Ltd

Tel: 0512-69209928 18796809688
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SuZhou Jonathan New Material Technology Co., Ltd.

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Beijing HwrkChemical Technology Co., Ltd

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Energy Chemical

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View Lastest Price from Tri(Ethylene Glycol) DI-P-Toluenesulfonate manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: (ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) 19249-03-7
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-24

Xian confluore Biological Technology Co., Ltd.

Product: Tos-PEG4-Tos 19249-03-7
Price: US $0.00/g
Min. Order: 500g
Purity: >98.00%
Supply Ability: 500g
Release date: 2024-03-27

Zhuozhou Wenxi import and Export Co., Ltd

Product: TRI(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE 19249-03-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

19249-03-7, Tri(Ethylene Glycol) DI-P-ToluenesulfonateRelated Search:

2,2-Dimethyl-1,3-propanediol Triethylene glycol dimethacrylate Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate) ALLYL ISOVALERATE Magnesium Bisglycinate 4-FLUORO-3'-IODODIPHENYL ETHER 5-NITRO-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER 1-CBZ-2-PIPERIDINECARBOXYLIC ACID Risedronic acid Benzonitrile, 3-bromo-2-fluoro- (9CI) Tos-PEG3-t-butyl ester TETRAETHYLENE GLYCOL DI-P-TOSYLATE TOS-PEG5-THP Tos-PEG7-t-butyl ester Tos-PEG9-t-butyl ester Tos-PEG5-CH2CO2t-butyl ester Tos-PEG13-t-butyl ester Tos-PEG3-CH2CO2tBu

1,10-Ditosyl-1,4,7,10-tetraoxadecane

1,8-Bis(tosyloxy)-3,6-dioxaoctane

Bis(4-methylbenzenesulfonic acid)3,6-dioxa-1,8-octanediyl ester

Bis(4-methylbenzenesulfonic acid)ethylenebis(oxyethylene) ester

Bis(p-toluenesulfonic acid)ethylenebisoxybisethylene ester

Triethylene glycol di-p-tosylate,98%

Triethleneglycol ditosylate

Triethylene glycol ditoluenesulfonate.

ETHANOL22OXYBIS21ETHANEDIYLOXYBISBIS4METHYLBENZENESULPHONATE

ethanol,2,2'-[oxybis(2,1-ethanediyloxy)]bis-,bis(4-methysbenzenesulfonate)

2,2μ-(Ethylenedioxy)diethyl ditosylate, Triethylene glycol ditosylate

1,2-Bis[2-(p-toluenesulfonyloxy)ethoxy]ethane(PEG3-Tos)

4-methylbenzenesulfonic acid 2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethyl ester

CAS_19249-03-7

1,2-Bis[2-(p-toluenesulfonyloxy)ethoxy]ethane 1,2-Bis(2-tosyloxyethoxy)ethane 2,2'-(Ethylenedioxy)diethyl Ditosylate Triethylene Glycol Di-p-tosylate

(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-Methylbenzenesulfonate)

Tos-PEG4-Tos

Tos-PEG3-Tos

PEG3-Tos 1,2-Bis[2-(p-toluenesulfonyloxy)ethoxy]ethane

Triethylene glycol bis(p-toluenesulfonate)≥ 98%(HPLC)

TRIETHYLENE GLYCOL BIS(P-TOLUENESULFONATE)

TRI(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE

TRIETHYLENE GLYCOL DI-P-TOSYLATE

TRIETHYLENE GLYCOL DITOSYLATE

TRIETHYLGLYCOL DI-P-TOSYLATE

LABOTEST-BB LT00248460

2,2'-(ETHYLENEDIOXY)DIETHYL DITOSYLATE

1,2-BIS[2-(P-TOLUENESULFONYLOXY)ETHOXY]ETHANE

1,2-BIS(2-TOSYLOXYETHOXY)ETHANE

2,2-(Ethylenedioxy)diethyl ditosylat

Bis-Tos-PEG3

Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-, 1,1'-bis(4-methylbenzenesulfonate)

2-2-2-(p-Tolylsulfonyloxy)ethoxyethoxyethyl 4-methylbenzenesulfonate

2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethyl4-methylbenzenesulfonate

Triethyleneglycol-di-p-toluenesulphonate

Triethylene glycol di(p-toluenesulfonate) 19249-03-7

TosO-(CH2CH2O)3-Tos

Tos-PEG3-Tos/Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-, 1,1'-bis(4-methylbenzenesulfonate)

(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) , Triethylene glycol bis(p-toluenesulfonate)

2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)ethyl 4-methylbenzene-1-sulfonate

Triethylene glycol di(<i>p</i>-toluenesulfonate)

Trivinyl glycol

(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfote)

TSO-PEG3-OTS

19249-03-7

C20H26O8S2

CH3C6H4SO3CH2CH2OCH22

Organic Building Blocks

Sulfur Compounds

Tosylates

Building Blocks