Tos-PEG5-CH2CO2t-butyl ester

Product Name: Tos-PEG5-CH2CO2t-butyl ester
CAS No.: 169751-73-9
Chemical Name: Tos-PEG5-CH2CO2t-butyl ester
Synonyms: Tos-PEG4-CH2-Boc;Tos-PEG5-CH2CO2tBu;Tos-PEG4-CH2COOtBu;Tos-PEG4-t-butyl acetate;Tos-PEG5-CH2CO2t-butyl ester;tert-butyl 14-(tosyloxy)-3,6,9,12-tetraoxatetradecanoate;2-(2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-;tert-Butyl 14-(tosyloxy)-3,6,9,12-tetraoxatetradecan-1-oate;tert-butyl 2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]acetate;2-(2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-acetic acid tert-butyl ester
CBNumber: CB23062692
Molecular Formula: C21H34O9S
Formula Weight: 462.55
MOL File: 169751-73-9.mol

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Tos-PEG5-CH2CO2t-butyl ester Property

Boiling point:: 550.0±50.0 °C(Predicted)
Density: 1.163±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS104010
Product name: Tos-PEG4-CH2COOtBu
Purity: 95+%
Packaging: 250mg
Price: $256
Updated: 2021/12/16

Activate Scientific

Product number: AS104010
Product name: Tos-PEG4-CH2COOtBu
Purity: 95+%
Packaging: 1g
Price: $583
Updated: 2021/12/16

BroadPharm

Product number: BP-22123
Product name: Tos-PEG5-CH2CO2tBu
Purity: 98%
Packaging: 500mg
Price: $620
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1860
Product name: Tos-PEG5-CH2CO2t-butyl ester
Packaging: 250mg
Price: $701
Updated: 2021/12/16

Matrix Scientific

Product number: 179756
Product name: [2-(2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-acetic acid tert-butyl ester
Purity: 95%
Packaging: 1g
Price: $1073
Updated: 2021/12/16

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Tos-PEG5-CH2CO2t-butyl ester Chemical Properties,Usage,Production

Description

Tos-PEG5-CH2CO2tBu is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Uses

Tos-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6

Tos-PEG5-CH2CO2t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Tos-PEG5-CH2CO2t-butyl ester Suppliers

China 41 India 1 United Kingdom 1 United States 4 Global 47

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
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Email: product02@bidepharm.com
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Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
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Shanghai YuanYe Biotechnology Co., Ltd.

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Jinan elephant international trading co., LTD

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Shanghai Chaolan Chemical Technology Center

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Shanghai Yihe Biological Technology Co., Ltd.

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Amatek Scientific Co. Ltd.

Tel: 0512-56316828
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Email: info@amateksci.com
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Aikon International Limited

Tel: 025-58859352 18068836627
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Email: sales01@aikonchem.com
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Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000 13917643586;
Email: admin@jingshipharmatech.com
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Shanghai Moss Medicine Technology Co., Ltd.

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Fax: QQ188369842
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169751-73-9, Tos-PEG5-CH2CO2t-butyl esterRelated Search:

Tos-PEG2-t-butyl ester Tos-PEG4-CH2CO2H Tos-PEG4-t-butyl ester Tos-PEG6-t-Butyl ester Tos-PEG3-CH2CO2tBu Tos-PEG9-t-butyl ester Tos-PEG7-t-butyl ester Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate) Tos-PEG21-Tos Tri(Ethylene Glycol) DI-P-Toluenesulfonate TETRAETHYLENE GLYCOL DI-P-TOSYLATE Tos-PEG13-t-butyl ester TOS-PEG5-THP Tos-PEG5 t-butyl ester Tos-PEG10-CH2CH2COOtBu Tos-PEG3-t-butyl ester Tos-PEG13-Tos (2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid tert-butyl ester

Tos-PEG5-CH2CO2t-butyl ester

Tos-PEG4-CH2COOtBu

Tos-PEG5-CH2CO2tBu

Tos-PEG4-CH2-Boc

3,6,9,12-Tetraoxatetradecanoic acid, 14-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester

tert-butyl 2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]acetate

2-(2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-acetic acid tert-butyl ester

Tos-PEG4-t-butyl acetate

tert-Butyl 14-(tosyloxy)-3,6,9,12-tetraoxatetradecan-1-oate

2-(2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-

Tos-PEG4-CH2COOtBu/3,6,9,12-Tetraoxatetradecanoic acid, 14-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester

tert-butyl 14-(tosyloxy)-3,6,9,12-tetraoxatetradecanoate

169751-73-9

C21H34O9S