Tos-PEG4-CH2CO2H

Product Name: Tos-PEG4-CH2CO2H
CAS No.: 1581248-63-6
Chemical Name: Tos-PEG4-CH2CO2H
Synonyms: Tos-PEG3-CH2COOH;Tos-PEG4-CH2CO2H;2-[2-[2-[2-(Tosyloxy)ethoxy]ethoxy]ethoxy]acetic Acid;2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]acetic acid;2-[2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)ethoxy]acetic acid;Acetic acid, 2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]-
CBNumber: CB83062689
Molecular Formula: C15H22O8S
Formula Weight: 362.4
MOL File: 1581248-63-6.mol

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Tos-PEG4-CH2CO2H Property

Boiling point:: 539.9±45.0 °C(Predicted)
Density: 1.280±0.06 g/cm3(Predicted)
solubility: Soluble in DCM
pka: 3.39±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22089
Product name: Tos-PEG4-CH2CO2H
Purity: 98%
Packaging: 250mg
Price: $290
Updated: 2021/12/16

BroadPharm

Product number: BP-22089
Product name: Tos-PEG4-CH2CO2H
Purity: 98%
Packaging: 500mg
Price: $485
Updated: 2021/12/16

BroadPharm

Product number: BP-22089
Product name: Tos-PEG4-CH2CO2H
Purity: 98%
Packaging: 1g
Price: $680
Updated: 2021/12/16

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Tos-PEG4-CH2CO2H Chemical Properties,Usage,Production

Description

Tos-PEG4-CH2CO2H is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Uses

Tos-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6

Tos-PEG4-CH2CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

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Tos-PEG4-CH2CO2H Suppliers

China 30 India 1 United Kingdom 1 United States 1 Global 33

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
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Jinan elephant international trading co., LTD

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Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
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Shanghai Yihe Biological Technology Co., Ltd.

Tel: 021-68882955 17721395025
Email: 2423903095@qq.com
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SHANGHAI FDC-CHEMICAL CO.,LTD

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Email: sales@fdc-chemical.com
Country: China
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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Wuhan Borenpharm Co., Ltd

Tel: 027-65563561 18717150066
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Changsha Bono New Materials Technology Co., Ltd.

Tel: 18191076804
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1581248-63-6, Tos-PEG4-CH2CO2HRelated Search:

Tos-PEG4-acid Tos-PEG5 t-butyl ester Tos-PEG2-CH2CO2tBu Tos-PEG2-t-butyl ester Tos-PEG4-t-butyl ester Tos-PEG6-t-Butyl ester Tos-PEG3-CH2CO2tBu Tos-PEG5-CH2CO2H Tos-PEG5-CH2CO2t-butyl ester Tos-PEG3-CH2CO2H

Tos-PEG4-CH2CO2H

Tos-PEG3-CH2COOH

Acetic acid, 2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]-

2-[2-[2-[2-(Tosyloxy)ethoxy]ethoxy]ethoxy]acetic Acid

2-[2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)ethoxy]acetic acid

2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]acetic acid

1581248-63-6