Tos-PEG3-CH2CO2H

Product Name: Tos-PEG3-CH2CO2H
CAS No.: 1807537-35-4
Chemical Name: Tos-PEG3-CH2CO2H
Synonyms: Tos-PEG2-CH2COOH;Tos-PEG3-CH2CO2H;2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)acetic acid;Acetic acid, 2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-
CBNumber: CB23062687
Molecular Formula: C13H18O7S
Formula Weight: 318.34
MOL File: 1807537-35-4.mol

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Tos-PEG3-CH2CO2H Property

Boiling point:: 512.8±40.0 °C(Predicted)
Density: 1.306±0.06 g/cm3(Predicted)
pka: 3.39±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Apolloscientific

Product number: BIPG1856
Product name: Tos-PEG3-CH2CO2H
Packaging: 250mg
Price: $681
Updated: 2021/12/16

BroadPharm

Product number: BP-22127
Product name: Tos-PEG3-CH2CO2H
Purity: 98%
Packaging: 1g
Price: $850
Updated: 2021/12/16

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Tos-PEG3-CH2CO2H Chemical Properties,Usage,Production

Description

Tos-PEG3-CH2CO2H is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Uses

Tos-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6

Tos-PEG3-CH2CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

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Tos-PEG3-CH2CO2H Suppliers

China 22 India 1 United Kingdom 1 United States 1 Global 25

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1807537-35-4, Tos-PEG3-CH2CO2HRelated Search:

Tos-PEG4-acid Tos-PEG5 t-butyl ester Tos-PEG2-CH2CO2tBu Tos-PEG2-t-butyl ester Tos-PEG4-CH2CO2H Tos-PEG4-t-butyl ester Tos-PEG6-t-Butyl ester Tos-PEG3-CH2CO2tBu Tos-PEG5-CH2CO2H Tos-PEG5-CH2CO2t-butyl ester

Tos-PEG3-CH2CO2H

Tos-PEG2-CH2COOH

Acetic acid, 2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-

2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)acetic acid

1807537-35-4