ChemicalBook > CAS DataBase List > Tos-PEG3-CH2CO2H
Tos-PEG3-CH2CO2H
- Product Name
- Tos-PEG3-CH2CO2H
- CAS No.
- 1807537-35-4
- Chemical Name
- Tos-PEG3-CH2CO2H
- Synonyms
- Tos-PEG2-CH2COOH;Tos-PEG3-CH2CO2H;2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)acetic acid;Acetic acid, 2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-
- CBNumber
- CB23062687
- Molecular Formula
- C13H18O7S
- Formula Weight
- 318.34
- MOL File
- 1807537-35-4.mol
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Tos-PEG3-CH2CO2H Property
- Boiling point:
- 512.8±40.0 °C(Predicted)
- Density
- 1.306±0.06 g/cm3(Predicted)
- pka
- 3.39±0.10(Predicted)
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N-Bromosuccinimide Price
Apolloscientific
- Product number
- BIPG1856
- Product name
- Tos-PEG3-CH2CO2H
- Packaging
- 250mg
- Price
- $681
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22127
- Product name
- Tos-PEG3-CH2CO2H
- Purity
- 98%
- Packaging
- 1g
- Price
- $850
- Updated
- 2021/12/16
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Tos-PEG3-CH2CO2H Chemical Properties,Usage,Production
Description
Tos-PEG3-CH2CO2H is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
Uses
Tos-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6
Tos-PEG3-CH2CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
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Tos-PEG3-CH2CO2H Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
1807537-35-4, Tos-PEG3-CH2CO2HRelated Search:
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