Tos-PEG3-CH2CO2tBu

Product Name: Tos-PEG3-CH2CO2tBu
CAS No.: 882518-89-0
Chemical Name: Tos-PEG3-CH2CO2tBu
Synonyms: Tos-PEG2-CH2-Boc;Tos-PEG2-CH2COOtBu;Tos-PEG3-CH2CO2tBu;tert-butyl 2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetate;{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-acetic acid tert-butyl ester;2-(2-(2-(paramethylbenzenesulfonylacyloxy)ethoxy)ethoxy)acetic acidtertbutyl ester;2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-Acetic acid, 1,1-dimethylethyl;Acetic acid, 2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester;Tos-PEG2-CH2COOtBu/Acetic acid, 2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester
CBNumber: CB53062688
Molecular Formula: C17H26O7S
Formula Weight: 374.45
MOL File: 882518-89-0.mol

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Tos-PEG3-CH2CO2tBu Property

storage temp.: Store at Room Tem.
solubility: Soluble in DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow

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Safety

HS Code: 2942000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS104008
Product name: Tos-PEG2-CH2COOtBu
Purity: 95+%
Packaging: 250mg
Price: $233
Updated: 2021/12/16

BroadPharm

Product number: BP-22090
Product name: Tos-PEG3-CH2CO2tBu
Purity: 98%
Packaging: 250mg
Price: $360
Updated: 2021/12/16

Activate Scientific

Product number: AS104008
Product name: Tos-PEG2-CH2COOtBu
Purity: 95+%
Packaging: 1g
Price: $532
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1859
Product name: Tos-PEG3-CH2CO2tBu
Packaging: 250mg
Price: $701
Updated: 2021/12/16

Matrix Scientific

Product number: 179765
Product name: {2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-acetic acid tert-butyl ester
Purity: 95%
Packaging: 1g
Price: $1156
Updated: 2021/12/16

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Tos-PEG3-CH2CO2tBu Chemical Properties,Usage,Production

Description

Tos-PEG3-CH2CO2tBu is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Uses

Tos-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6

Tos-PEG3-CH2CO2tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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Tos-PEG3-CH2CO2tBu Suppliers

China 39 India 1 United Kingdom 1 United States 2 Global 43

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
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Jinan elephant international trading co., LTD

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Shanghai Yihe Biological Technology Co., Ltd.

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Amatek Scientific Co. Ltd.

Tel: 0512-56316828
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Country: China
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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Nextpeptide Inc

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Email: sales@nextpeptide.com
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Changsha Bono New Materials Technology Co., Ltd.

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Changzhou Kechem Bio-Scientific Co., LTD.

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882518-89-0, Tos-PEG3-CH2CO2tBuRelated Search:

Tos-PEG2-t-butyl ester Tos-PEG4-CH2CO2H Tos-PEG4-t-butyl ester Tos-PEG6-t-Butyl ester Tos-PEG5-CH2CO2H Tos-PEG9-t-butyl ester Tos-PEG7-t-butyl ester Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-Methylbenzenesulfonate) Tos-PEG21-Tos Tri(Ethylene Glycol) DI-P-Toluenesulfonate TETRAETHYLENE GLYCOL DI-P-TOSYLATE Tos-PEG13-t-butyl ester TOS-PEG5-THP Tos-PEG5 t-butyl ester Tos-PEG10-CH2CH2COOtBu Tos-PEG3-t-butyl ester Tos-PEG13-Tos (2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-acetic acid tert-butyl ester

Tos-PEG3-CH2CO2tBu

Tos-PEG2-CH2COOtBu

tert-butyl 2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetate

2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-Acetic acid, 1,1-dimethylethyl

Tos-PEG2-CH2-Boc

Acetic acid, 2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester

{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-acetic acid tert-butyl ester

Tos-PEG2-CH2COOtBu/Acetic acid, 2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester

2-(2-(2-(paramethylbenzenesulfonylacyloxy)ethoxy)ethoxy)acetic acidtertbutyl ester

882518-89-0

C17H26O7S