ChemicalBook > CAS DataBase List > 4-Amino-2,6-difluorophenol

4-Amino-2,6-difluorophenol

Product Name
4-Amino-2,6-difluorophenol
CAS No.
126058-97-7
Chemical Name
4-Amino-2,6-difluorophenol
Synonyms
4-AMINO-2,6-DIFLUOROPHENOL;4-amino-2,6-difluoropheneol;Phenol, 4-amino-2,6-difluoro-;3,5-Difluoro-4-hydroxyaniline;4-Amino-2,6-difluorophenol ISO 9001:2015 REACH
CBNumber
CB1352391
Molecular Formula
C6H5F2NO
Formula Weight
145.11
MOL File
126058-97-7.mol
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4-Amino-2,6-difluorophenol Property

Melting point:
0°C
Boiling point:
0°C
Density 
1.472±0.06 g/cm3(Predicted)
Flash point:
0°C
storage temp. 
Sealed in dry,Room Temperature
pka
7.72±0.23(Predicted)
form 
solid
color 
Brown
CAS DataBase Reference
126058-97-7
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
HS Code 
2908990000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A610735
Product name
4-amino-2,6-difluorophenol
Packaging
500mg
Price
$220
Updated
2021/12/16
Apolloscientific
Product number
PC8311
Product name
4-Amino-2,6-difluorophenol
Purity
95%
Packaging
1g
Price
$90
Updated
2021/12/16
SynQuest Laboratories
Product number
4656-3-46
Product name
4-Amino-2,6-difluorophenol
Purity
90%
Packaging
250mg
Price
$95
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA64415
Product name
4-Amino-2,6-difluorophenol
Packaging
500mg
Price
$150
Updated
2021/12/16
SynQuest Laboratories
Product number
4656-3-46
Product name
4-Amino-2,6-difluorophenol
Purity
90%
Packaging
1g
Price
$195
Updated
2021/12/16
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4-Amino-2,6-difluorophenol Chemical Properties,Usage,Production

Synthesis

847861-84-1

126058-97-7

General procedure for the synthesis of 4-amino-2,6-difluorophenol from 2-(benzyloxy)-1,3-difluoro-5-nitrobenzene: To a solution of 2-(benzyloxy)-1,3-difluoro-5-nitrobenzene (5.3 g, 20 mmol) in ethanol (100 mL) was added 10% palladium/activated carbon (1.5 g). The reaction mixture was stirred overnight at room temperature and 1 atmosphere of hydrogen at 1 atm. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford 4-amino-2,6-difluorophenol (2.9 g, 95% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.68 (br s, 1H), 6.19 (d, J = 10.8 Hz, 2H), 5.01 (s, 2H).

References

[1] Patent: WO2010/51373, 2010, A1. Location in patent: Page/Page column 68

4-Amino-2,6-difluorophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Amino-2,6-difluorophenol manufacturers

Career Henan Chemical Co
Product
4-Amino-2,6-difluorophenol 126058-97-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-12