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Methyl 3-amino-2-pyrazinecarboxylate

Product Name
Methyl 3-amino-2-pyrazinecarboxylate
CAS No.
16298-03-6
Chemical Name
Methyl 3-amino-2-pyrazinecarboxylate
Synonyms
METHYL 3-AMINOPYRAZINE-2-CARBOXYLATE;3-AMINOPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER;AKOS 90402;NSC 123649;BUTTPARK 35\02-15;TIMTEC-BB SBB004048;Methyl 3-amino-2-pyr;2-aMino-pyrazine-2-Methyl;3-amino-2-pyrazinecarboxyL;methyl 3-aminopyrazinecarboxylate
CBNumber
CB1353338
Molecular Formula
C6H7N3O2
Formula Weight
153.14
MOL File
16298-03-6.mol
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Methyl 3-amino-2-pyrazinecarboxylate Property

Melting point:
169-172 °C (lit.)
Boiling point:
300.8±37.0 °C(Predicted)
Density 
1.319±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Chloroform, Methanol
pka
-0.30±0.10(Predicted)
form 
Crystalline Powder
color 
Yellow
BRN 
127495
InChIKey
INCSQLZZXBPATR-UHFFFAOYSA-N
LogP
0.2 at 20℃ and pH7
Surface tension
73.3mN/m at 1g/L and 20℃
CAS DataBase Reference
16298-03-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-37/39-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
276154
Product name
Methyl 3-amino-2-pyrazinecarboxylate
Purity
97%
Packaging
10g
Price
$67.8
Updated
2024/03/01
TCI Chemical
Product number
A1186
Product name
Methyl 3-Aminopyrazine-2-carboxylate
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
A1186
Product name
Methyl 3-Aminopyrazine-2-carboxylate
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
A1186
Product name
Methyl 3-Aminopyrazine-2-carboxylate
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$120
Updated
2024/03/01
TRC
Product number
A628935
Product name
3-Amino-2-pyrazinecarboxylicAcidMethylEster
Packaging
1g
Price
$45
Updated
2021/12/16
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Methyl 3-amino-2-pyrazinecarboxylate Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline powder

Uses

Methyl 3-amino-2-pyrazinecarboxylate has been used in:

  • synthesis of 2-arylpteridin-4-ones and piperazine-derived 2-furan-2-yl-[1,2,4]triazolo[1,5-a] pyrazines
  • reactions with isocyanates and aroyl chlorides for conversion to pteridinediones

Definition

ChEBI: Methyl 3-aminopyrazine-2-carboxylate is a pyrazine that is substituted by a methoxycarbonyl group at position 2 and an amino group at position 3. It is a member of pyrazines, a methyl ester and an aromatic amine.

Purification Methods

The ester forms yellow needles from H2O (100 parts using charcoal). If it contains the free acid (see IR), then dissolve it in CH2Cl2, wash it with saturated aqueous Na2CO3, brine, dry over MgSO4 filter, evaporate and recrystallise the residue. The free acid has m 203-204o (dec) [UV: Brown & Mason J Chem Soc 3443 1956] and pK1 <1 and pK2 3.70. The ammonium salt has m 232o(dec) (from aqueous Me2CO) and the amide has m 239.2o (from H2O) [Ellingson et al. J Am Chem Soc 67 1711 1945]. [Beilstein 25 III/IV 4412.]

Methyl 3-amino-2-pyrazinecarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 3-amino-2-pyrazinecarboxylate Suppliers

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View Lastest Price from Methyl 3-amino-2-pyrazinecarboxylate manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
Methyl 3-amino-2-pyrazinecarboxylate 16298-03-6
Price
US $999.00-666.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-20
Hebei Zhanyao Biotechnology Co. Ltd
Product
Methyl 3-amino-2-pyrazinecarboxylate 16298-03-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-13
Honest Joy Holdings Limited
Product
Methyl 3-amino-2-pyrazinecarboxylate 16298-03-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99.3%
Supply Ability
100 tons
Release date
2022-02-08

16298-03-6, Methyl 3-amino-2-pyrazinecarboxylateRelated Search:

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