Oleyl alcohol
- Product Name
- Oleyl alcohol
- CAS No.
- 143-28-2
- Chemical Name
- Oleyl alcohol
- Synonyms
- Satol;oleyl;9-OCTADECEN-1-OL;OLEIC ALCOHOL;(Z)-9-Octadecen-1-ol;(Z)-Octadec-9-en-1-ol;Olely Alcohol;Olive alcohol;9-Octadecen-1-ol,(Z)-;9-Octadecen-1-ol, (Z)-
- CBNumber
- CB1353439
- Molecular Formula
- C18H36O
- Formula Weight
- 268.48
- MOL File
- 143-28-2.mol
Oleyl alcohol Property
- Melting point:
- 0-5.0 °C (lit.)
- Boiling point:
- 207 °C/13 mmHg (lit.)
- Density
- 0.849 g/mL at 25 °C (lit.)
- vapor pressure
- 10.64 hPa (195 °C)
- FEMA
- 4363 | CIS-9-OCTADECENOL
- refractive index
- n20/D 1.46(lit.)
- Flash point:
- >230 °F
- storage temp.
- -20°C
- solubility
- Soluble in ethanol (95%), and ether; practically insoluble in water.
- form
- Viscous Liquid
- pka
- 15.20±0.10(Predicted)
- color
- Clear almost colorless to yellow
- Odor
- fatty animal
- Odor Type
- fatty
- Water Solubility
- Miscible with alcohol and ether. Slightly miscible with carbon tetrachloride. Immiscible with water.
- Merck
- 14,6831
- JECFA Number
- 1637
- BRN
- 1723962
- Stability:
- Stable. Combustible. Incompatible with strong acids, strong oxidizing agents.
- LogP
- 7.07 at 25℃
- CAS DataBase Reference
- 143-28-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Oleyl Alcohol(143-28-2)
- EPA Substance Registry System
- 9-Octadecen-1-ol, (9Z)- (143-28-2)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 38
- Safety Statements
- 26-36
- WGK Germany
- -
- RTECS
- RG4120000
- TSCA
- Yes
- HS Code
- 29052990
- Hazardous Substances Data
- 143-28-2(Hazardous Substances Data)
- Toxicity
- LD50 orally in Rabbit: > 5000 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H320Causes eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 8.20923
- Product name
- cis-9-Octadecen-1-ol
- Purity
- for synthesis
- Packaging
- 100mL
- Price
- $41.4
- Updated
- 2024/03/01
- Product number
- 8.20923
- Product name
- cis-9-Octadecen-1-ol
- Purity
- for synthesis
- Packaging
- 1L
- Price
- $75.1
- Updated
- 2024/03/01
- Product number
- 8.20923
- Product name
- cis-9-Octadecen-1-ol
- Purity
- for synthesis
- Packaging
- 2.5L
- Price
- $164
- Updated
- 2024/03/01
- Product number
- 1478185
- Product name
- Oleyl alcohol
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 5x50mg
- Price
- $474
- Updated
- 2024/03/01
- Product number
- 08066
- Product name
- Oleyl alcohol
- Purity
- analytical standard
- Packaging
- 100mg
- Price
- $82.8
- Updated
- 2024/03/01
Oleyl alcohol Chemical Properties,Usage,Production
Chemical Properties
Colourless or light yellow liquid.
Chemical Properties
Oleyl alcohol occurs as a pale yellow oily liquid that gives off acrid fumes when heated.
Chemical Properties
Colorless to light yellow liquid; fatty aroma with animal undertones.
Uses
Oleyl alcohol is used in softening and lubrication of textile fabrics, and in the production of carbon paper, stencil paper, and printing ink. It finds application in cosmetic products viz skin creams and lotions as a thickner, hair conditioners and hair coating shampoos. It is utilized as an antifoaming agent and cutting lubricant, as the precursor for the preparation of its sulfuric ester derivatives, which are used in detergents and wetting agents. It plays a vital role in various formulations for drug delivery.
Uses
Chiefly in the manufacture of its sulfuric esters which are detergents and wetting agents, as an antifoam agent; metal cutting lubricant; in carbon paper, stencil paper, printing ink; as a plasticizer; for softening and lubricating textile fabrics; carrier for medicaments.
Uses
oleyl alcohol is an emollient, solvent, viscosity-increasing agent, and carrier employed in a wide variety of cosmetic formulations including makeup, skin care, and hand and body preparations. oleyl alcohol is an unsaturated fatty alcohol found in fish oils and can also be produced synthetically. According to some sources, it is comedogenic and has a mild irritancy potential.
Definition
ChEBI: A long chain fatty alcohol that is octadecanol containing a double bond located at position 9 (the Z-geoisomer).
Production Methods
Oleyl alcohol occurs naturally in fish oils. Synthetically, it can be prepared from butyl oleate by a Bouveault–Blanc reduction with sodium and butyl alcohol. An alternative method of manufacture is by the hydrogenation of triolein in the presence of zinc chromite.
brand name
Witcohol 85 (Witco); Witcohol 90 (Witco).
Aroma threshold values
Fatty-type, medium strength odor.
General Description
Oleyl alcohol has been reported as an effective solvent for oil/water-type tacrolimus (FK506) cream formulation, useful for atopic dermatitis treatment. It was reported as diluting agent for Alamine 336. Palm oil esters derived from oleyl alcohol, have potential applications in the cosmetic and pharmaceutical industries due to the excellent wetting behavior of the esters without the oily feel.
Flammability and Explosibility
Non flammable
Pharmaceutical Applications
Oleyl alcohol is mainly used in topical pharmaceutical formulations
and has been used in transdermal delivery formulations.It has
been utilized in the development of biodegradable injectable
thermoplastic oligomers,and in aerosol formulations of insulin
and albuterol.
Therapeutically, it has been suggested that oleyl alcohol may
exhibit antitumor properties via transmembrane permeation.
Safety Profile
A human skin and eye irritant. Aningredient in cosmetics. When heated to decomposition itemits acrid smoke and irritating fumes.
Safety
Oleyl alcohol is mainly used in topical pharmaceutical formulations
and is generally regarded as a nontoxic and nonirritant material at
the levels employed as an excipient. However, contact dermatitis
due to oleyl alcohol has been reported.
The results of acute oral toxicity and percutaneous studies in
animals with products containing 8% oleyl alcohol indicate a very
low toxicity. Formulations containing 8% or 20% oleyl alcohol
administered by gastric intubation, at doses up to 10 g/kg bodyweight,
caused no deaths and no toxic effects in rats.
storage
The bulk material should be stored in a well-closed container in a cool, dry, place.
Purification Methods
Purify it by fractional crystallisation at -40o from acetone, then distil it under vacuum. [Beilstein 2 IV 2204.]
Regulatory Status
Included in the FDA Inactive Ingredients Database (topical emulsions and ointments). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Oleyl alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Oleyl alcohol manufacturers
- Product
- Oleyl alcohol 143-28-2
- Price
- US $6.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20TONS
- Release date
- 2024-05-06
- Product
- Oleyl alcohol 143-28-2
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-15
- Product
- Oleylalcohol 143-28-2
- Price
- US $60.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-05-17