Erythrodiol
- Product Name
- Erythrodiol
- CAS No.
- 545-48-2
- Chemical Name
- Erythrodiol
- Synonyms
- Aids064685;ERYTHODIOL;Aids-064685;ERYTHRODIOL;ERYTHRODIOL(P);HOMOOLESTRANOL;3β-Erythrodiol;Erythrodiol-RM;3b-Erythrodiol;ERYTHRODIOL(SH)
- CBNumber
- CB9111279
- Molecular Formula
- C30H50O2
- Formula Weight
- 442.72
- MOL File
- 545-48-2.mol
Erythrodiol Property
- Melting point:
- 230-231 °C(lit.)
- Boiling point:
- 520.5±50.0 °C(Predicted)
- Density
- 1.05±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly, Sonicated), Methanol (Slightly)
- pka
- 15.09±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- insoluble in water
- BRN
- 2340203
- InChIKey
- PSZDOEIIIJFCFE-MMIPUHLFNA-N
- SMILES
- [C@@]12(C)CC[C@@]3(CO)CCC(C)(C)C[C@@]3([H])C1=CC[C@]1([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]21C |&1:0,4,13,18,20,24,29,33,r|
- LogP
- 9.180 (est)
- CAS DataBase Reference
- 545-48-2(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SML4121
- Product name
- Erythrodiol
- Purity
- ≥98% (HPLC)
- Packaging
- 1 unit
- Price
- $299
- Updated
- 2025/07/31
- Product number
- 09258
- Product name
- Erythrodiol
- Purity
- analytical standard
- Packaging
- 10mg
- Price
- $231
- Updated
- 2025/07/31
- Product number
- 30135
- Product name
- Erythrodiol
- Packaging
- 5mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 30135
- Product name
- Erythrodiol
- Packaging
- 50mg
- Price
- $553
- Updated
- 2024/03/01
- Product number
- 30135
- Product name
- Erythrodiol
- Packaging
- 10mg
- Price
- $143
- Updated
- 2024/03/01
Erythrodiol Chemical Properties,Usage,Production
Description
Erythrodiol is a triterpene that has been found in olive oil and has diverse biological activities. It induces relaxation of isolated rat aortic rings precontracted with phenylephrine (EC50 = 3.38 μM). Erythrodiol inhibits the growth of HT-29 adenocarcinoma cells (EC50 = 48.8 μM). It induces production of reactive oxygen species (ROS) and apoptosis in MCF-7 cells when used at a concentration of 100 μM. Topical administration of erythrodiol (0.5 mg/ear) reduces ear edema and myeloperoxidase (MPO) activity induced by phorbol 12-myristate 13-acetate (TPA; ) in mice.
Uses
It is an essential reagent in the synthesis of aminopropoxytriterpenoids that have anticancer activity. 3β-Erythrodiol has pharmacological property as a vasodilatory agent. It may have interesting therapeutic potential as a new vasodilator drug, for protecting the cardiovascular system.
Definition
ChEBI: Erythrodiol is a pentacyclic triterpenoid that is beta-amyrin in which one of the hydrogens of the methyl group at position 28 has been replaced by a hydroxy group. It is a plant metabolite found in olive oil as well as in Rhododendron ferrugineum and other Rhododendron species. It has a role as a plant metabolite. It is a pentacyclic triterpenoid, a primary alcohol, a secondary alcohol and a diol. It is functionally related to a beta-amyrin.
References
[1] ROSALíA RODRíGUEZ-RODRíGUEZ. Potential vasorelaxant effects of oleanolic acid and erythrodiol, two triterpenoids contained in “orujo” olive oil, on rat aorta.[J]. British Journal of Nutrition, 2004, 92 4: 635-642. DOI: 10.1079/bjn20041231
[2] M. EMíLIA JUAN. Erythrodiol, a natural triterpenoid from olives, has antiproliferative and apoptotic activity in HT-29 human adenocarcinoma cells[J]. Molecular Nutrition & Food Research, 2008, 52 5: 595-599. DOI: 10.1002/mnfr.200700300
[3] YOSRA ALLOUCHE. Antioxidant, Antiproliferative, and Pro-apoptotic Capacities of Pentacyclic Triterpenes Found in the Skin of Olives on MCF-7 Human Breast Cancer Cells and Their Effects on DNA Damage[J]. Journal of Agricultural and Food Chemistry, 2010, 59 1: 121-130. DOI: 10.1021/jf102319y
[4] SALVADOR Má?EZ. Effect of selected triterpenoids on chronic dermal inflammation[J]. European journal of pharmacology, 1997, 334 1: Pages 103-105. DOI: 10.1016/s0014-2999(97)01187-4
Erythrodiol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Erythrodiol manufacturers
- Product
- Erythrodiol 545-48-2
- Price
- US $45.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-12-05
- Product
- Erythrodiol 545-48-2
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,50kg
- Release date
- 2020-01-18