5-THIO-D-GLUCOSE
- Product Name
- 5-THIO-D-GLUCOSE
- CAS No.
- 20408-97-3
- Chemical Name
- 5-THIO-D-GLUCOSE
- Synonyms
- d-glucos;NSC 204984;THIOGLUCOSE;5-Thioglucose;5-THIO-D-GLUCOSE;GLUCOTHIOPYRANOSE;D-Glucose, 5-thio-;5-Thio-D-glucose ,98%;α-D-Glucothiopyranose;5-Thio-α-D-glucopyranose
- CBNumber
- CB1358757
- Molecular Formula
- C6H12O5S
- Formula Weight
- 196.22
- MOL File
- 20408-97-3.mol
5-THIO-D-GLUCOSE Property
- Melting point:
- 135-138 °C(lit.)
- Boiling point:
- 303.11°C (rough estimate)
- Density
- 1.271 (estimate)
- refractive index
- 1.5060 (estimate)
- storage temp.
- 2-8°C
- solubility
- Soluble in Water (up to 15 mg/ml)
- form
- Powder
- pka
- 9.11±0.10(Predicted)
- color
- White
- optical activity
- [α]/D 220.0±5.0°, c = 1 in 0.1 M HCl
- Water Solubility
- Miscible with water.
- Merck
- 13,9408
- BRN
- 1865193
- Stability:
- Stable for 2 years as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.
- CAS DataBase Reference
- 20408-97-3
- EPA Substance Registry System
- D-Glucose, 5-thio- (20408-97-3)
N-Bromosuccinimide Price
- Product number
- 88635
- Product name
- 5-Thio-D-glucose
- Purity
- ≥98.0% (HPLC)
- Packaging
- 1g
- Price
- $1750
- Updated
- 2024/03/01
- Product number
- J63621
- Product name
- 5-Thio-D-glucose, 97+%
- Packaging
- 25mg
- Price
- $181
- Updated
- 2023/06/20
- Product number
- T350725
- Product name
- 5-Thio-D-glucose
- Packaging
- 0.5mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 294755
- Product name
- 5-Thio-D-glucose
- Packaging
- 25mg
- Price
- $340
- Updated
- 2021/12/16
- Product number
- 161986
- Product name
- 5-Thio-D-glucose
- Packaging
- 10mg
- Price
- $425
- Updated
- 2021/12/16
5-THIO-D-GLUCOSE Chemical Properties,Usage,Production
Description
5-Thio-D-glucose (20408-97-3) is a potent competitive inhibitor of the cellular transport of glucose and glucose-mediated insulin release.1 May be used to induce a state of glucose deprivation in laboratory animals.2 Stimulates feeding in rat models.3? Induces Alzheimer-like changes in frontal cortex and hippocampus in rats.4? Elevates renal TGF-b1 at a dose that does not prevent streptozotocin diabetes in rats.5
Uses
5-Thio-D-glucose (cas# 20408-97-3) is a compound useful in organic synthesis.
References
Wang et al. (1995) Glucose transporter 2 expression: prevention of streptozotocin-induced reduction in beta-cells with 5-thio-D-glucose; Clin. Endocrinol. Diabetes, 103 83 Suppl.2 Shah et al. (2019), Recurrent glucose deprivation leads to the preferential use of lactate by neurons in the ventromedial hypothalamus; J. Physiol. Endocrinol. Metab., 316 E948 Li et al. (2014), Stimulation of feeding by three different glucose-sensing mechanisms requires hindbrain catecholamine neurons; J. Physiol. Regul. Integr. Comp. Physiol., 306 R257 Salkovic-Petrisic et al. (2006), Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signaling pathway; J. Neurochem., 96 1005 Lane et al. (2000), 5-thio-D-glucose elevates renal transforming growth factor beta-1 at a dose that does not prevent streptozotocin diabetes in rats; Endocrinology, 141 3337
5-THIO-D-GLUCOSE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-THIO-D-GLUCOSE manufacturers
- Product
- 5-Thio-D-glucose 20408-97-3
- Price
- US $0.00/G
- Min. Order
- 10G
- Purity
- 98%min
- Supply Ability
- 30kg/month
- Release date
- 2023-02-14
- Product
- 5-THIO-D-GLUCOSE 20408-97-3
- Price
- US $1.00/KG
- Min. Order
- 1G
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-08-15