ChemicalBook > CAS DataBase List > 5-THIO-D-GLUCOSE

5-THIO-D-GLUCOSE

Product Name: 5-THIO-D-GLUCOSE
CAS No.: 20408-97-3
Chemical Name: 5-THIO-D-GLUCOSE
Synonyms: d-glucos;NSC 204984;THIOGLUCOSE;5-Thioglucose;5-THIO-D-GLUCOSE;GLUCOTHIOPYRANOSE;D-Glucose, 5-thio-;5-Thio-D-glucose ,98%;α-D-Glucothiopyranose;5-Thio-α-D-glucopyranose
CBNumber: CB1358757
Molecular Formula: C6H12O5S
Formula Weight: 196.22
MOL File: 20408-97-3.mol

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5-THIO-D-GLUCOSE Property

Melting point:: 135-138 °C(lit.)
Boiling point:: 303.11°C (rough estimate)
Density: 1.271 (estimate)
refractive index: 1.5060 (estimate)
storage temp.: 2-8°C
solubility: Soluble in Water (up to 15 mg/ml)
form: Powder
pka: 9.11±0.10(Predicted)
color: White
optical activity: [α]/D 220.0±5.0°, c = 1 in 0.1 M HCl
Water Solubility: Miscible with water.
Merck: 13,9408
BRN: 1865193
Stability:: Stable for 2 years as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.
CAS DataBase Reference: 20408-97-3
EPA Substance Registry System: D-Glucose, 5-thio- (20408-97-3)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
RTECS: LZ7500000
F: 3-10-23
Toxicity: mouse,LD50,intraperitoneal,5500mg/kg (5500mg/kg),International Journal of Radiation Oncology, Biology, Physics. Vol. 8, Pg. 589, 1982.

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 88635
Product name: 5-Thio-D-glucose
Purity: ≥98.0% (HPLC)
Packaging: 1g
Price: $1260
Updated: 2025/07/31

TRC

Product number: T350725
Product name: 5-Thio-D-glucose
Packaging: 0.5mg
Price: $165
Updated: 2021/12/16

Usbiological

Product number: 294755
Product name: 5-Thio-D-glucose
Packaging: 25mg
Price: $340
Updated: 2021/12/16

Usbiological

Product number: 161986
Product name: 5-Thio-D-glucose
Packaging: 10mg
Price: $425
Updated: 2021/12/16

Biosynth Carbosynth

Product number: MT04882
Product name: 5-Thio-D-glucose
Packaging: 500mg
Price: $450
Updated: 2021/12/16

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5-THIO-D-GLUCOSE Chemical Properties,Usage,Production

Description

5-Thio-D-glucose (20408-97-3) is a potent competitive inhibitor of the cellular transport of glucose and glucose-mediated insulin release.1 May be used to induce a state of glucose deprivation in laboratory animals.2 Stimulates feeding in rat models.3? Induces Alzheimer-like changes in frontal cortex and hippocampus in rats.4? Elevates renal TGF-b1 at a dose that does not prevent streptozotocin diabetes in rats.5

Uses

5-Thio-D-glucose (cas# 20408-97-3) is a compound useful in organic synthesis.

References

[1] Z WANG H G. Glucose transporter 2 expression: prevention of streptozotocin-induced reduction in beta-cells with 5-thio-D-glucose.[J]. Experimental and Clinical Endocrinology & Diabetes, 1995, 103 Suppl 2: 83-97. DOI:10.1055/s-0029-1211400
[2] MAITREYEE SHAH. Recurrent glucose deprivation leads to the preferential use of lactate by neurons in the ventromedial hypothalamus.[J]. American journal of physiology. Endocrinology and metabolism, 2019, 316 5: E948-E955. DOI:10.1152/ajpendo.00468.2018
[3] AI-JUN LI. Stimulation of feeding by three different glucose-sensing mechanisms requires hindbrain catecholamine neurons.[J]. American journal of physiology. Regulatory, integrative and comparative physiology, 2014, 306 4: R257-64. DOI:10.1152/ajpregu.00451.2013
[4] MELITA SALKOVIC-PETRISIC. Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway[J]. Journal of Neurochemistry, 2006, 96 4: 1005-1015. DOI:10.1111/j.1471-4159.2005.03637.x
[5] LANE P. 5-thio-D-glucose elevates renal transforming growth factor beta-1 at a dose that does not prevent streptozocine diabetes in rats.[J]. Endocrinology, 2000, 26 1: 3337-3342. DOI:10.1210/en.141.9.3337

5-THIO-D-GLUCOSE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-THIO-D-GLUCOSE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Thio-D-glucose 20408-97-3
Price: US $0.00/G
Min. Order: 10G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-14

Career Henan Chemical Co

Product: 5-THIO-D-GLUCOSE 20408-97-3
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-15

20408-97-3, 5-THIO-D-GLUCOSERelated Search:

5-THIO-D-GLUCOSE 4-MERCAPTO-1-BUTANOL 6-Mercaptohexan-1-ol N-BUTYL ETHYL SULFIDE ISOPROPYL METHYL SULFIDE 3-Methylthiopropanol 2-Mercapto-3-butanol 4-(METHYLTHIO)BUTANOL 3-(ETHYLTHIO)PROPANOL ETHYL ISOPROPYL SULFIDE SEC-BUTYL METHYL SULFIDE Ethyl 2-hydroxyethyl sulfide 1-Hexanethiol 2-(ISOPROPYLTHIO)ETHANOL TETRAHYDROTHIOPYRAN-4-OL 97 ISOPROPYL N-PROPYL SULFIDE Thiane 2-(N-PROPYLTHIO)ETHANOL

5-Thio-α-D-glucopyranose

α-D-Glucothiopyranose

5-Thio-D-glucose,predominantly &-anomer

5-Thio-D-glucose, alpha-anomer

5-Thio-D-glucose ,98%

NSC 204984

5-Thio-D-glucose, ≥98.0% (HPLC)

(2R,3R,4S,5R)-2,3,4,6-Tetrahydroxy-5-mercaptohexanal

-2,3,4,6-Tetrahydroxy-5-mercaptohexanal

5-thio-alpha-d-glucopyranose

alpha-d-glucothiopyranose

d-glucos

5-THIO-D-GLUCOSE

5-Thioglucose

GLUCOTHIOPYRANOSE

THIOGLUCOSE

5-THIO-D -GLUCOSE CRYSTALLINE

5-THIO-D-GLUCOSE, 96%, PREDOMINANTLY ALP HA-ANOMER

5-Deoxy-5-mercapto-D-glucose

(2S)-6β-(Hydroxymethyl)tetrahydro-2H-thiopyran-2α,3α,4β,5α-tetraol

5-O-Thia-α-D-glucopyranose

4-[2,4-bis(4-morpholinyl)-8-pyrimido[5,4-d]pyrimidinyl]morpholine

D-Glucose, 5-thio-

5-THIO-D-GLUCOSE USP/EP/BP

(2R,3R,4S,5R)-2,3,4,6-tetrahydroxy-5-sulfanylhexanal

5-Thio-<sc>D</sc>-glucose

20408-97-3

C6H12O5S

Biochemicals and Reagents

BioChemical

Carbohydrate Synthesis

Carbohydrates

Monosaccharide

Monosaccharides

Specialty Synthesis

13C & 2H Sugars

Carbohydrates & Derivatives

Sulfur & Selenium Compounds

Biochemicals and Reagents

Carbohydrates

Monosaccharide