Bupivacaine hydrochloride
- Product Name
- Bupivacaine hydrochloride
- CAS No.
- 14252-80-3
- Chemical Name
- Bupivacaine hydrochloride
- Synonyms
- Sensorcaine;ah-2250;Bupivocoine HCl;Bupivacaine HCI;Bupivacaine HCL API;marcainehydrochloride;Bupivacaine HCL (USP);BUPIVACAINE HYDROCHLORIDE;Bupivacaine Hydrochloride, USP;Bupivacaine hydrochloride,>98%
- CBNumber
- CB1386202
- Molecular Formula
- C18H28N2O.ClH
- Formula Weight
- 324.89
- MOL File
- 14252-80-3.mol
Bupivacaine hydrochloride Property
- Melting point:
- 249-2510C
- storage temp.
- Refrigerator
- solubility
- Soluble in water, freely soluble in alcohol.
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H
- InChIKey
- SIEYLFHKZGLBNX-UHFFFAOYSA-N
- SMILES
- C1(CCCCN1CCCC)C(=O)NC1C(C)=CC=CC=1C.Cl
- CAS DataBase Reference
- 14252-80-3(CAS DataBase Reference)
Safety
- Hazard Codes
- T+
- Risk Statements
- 26/27/28
- Safety Statements
- 22-36/37/39-45
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- RTECS
- TK6125000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 2933399090
- Toxicity
- LD50 in mice (mg/kg): 7.8 i.v., 82 s.c. (Henn, Brattsand)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H310Fatal in contact with skin
H330Fatal if inhaled
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P350IF ON SKIN: Gently wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P310Immediately call a POISON CENTER or doctor/physician.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P361Remove/Take off immediately all contaminated clothing.
P363Wash contaminated clothing before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 1078507
- Product name
- Bupivacaine hydrochloride
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 300mg
- Price
- $467
- Updated
- 2025/07/31
- Product number
- B780598
- Product name
- Bupivacaine hydrochloride
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B780598
- Product name
- Bupivacaine hydrochloride
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- API0001784
- Product name
- BUPIVACAINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $140.7
- Updated
- 2021/12/16
- Product number
- CD11259235
- Product name
- 1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamidehydrochloride
- Purity
- 97%
- Packaging
- 10g
- Price
- $38
- Updated
- 2021/12/16
Bupivacaine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
antineoplastic
Uses
Bupivacaine Hydrochloride is the salt form of Bupivacaine (B689561); is a sodium channel blocker, local anesthetic.
Definition
ChEBI: Bupivacaine hydrochloride (anhydrous) is a racemate composed of equimolar amounts of dextrobupivacaine hydrochloride and levobupivacaine hydrochloride. The monohydrate form is commonly used as a local anaesthetic. It has a role as an adrenergic antagonist, an amphiphile, an EC 3.1.1.8 (cholinesterase) inhibitor, an EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor and a local anaesthetic. It contains a levobupivacaine hydrochloride (anhydrous), a dextrobupivacaine hydrochloride (anhydrous) and a bupivacaine(1+).
brand name
Marcaine (Hospira); Sensorcaine (AstraZeneca).
Biological Functions
Bupivacaine hydrochloride (Marcaine, Sensorcaine) has particularly long action, and some nerve blocks last more than 24 hours; this is often an advantage for postoperative analgesia. Its use for epidural anesthesia in obstetrics has attracted interest because it can relieve the pain of labor at concentrations as low as 0.125% while permitting some motor activity of abdominal muscles to aid in expelling the fetus. The lower concentration minimizes the possibility of cardiac toxicity. Fetal drug concentrations remain low, and drug-induced neurobehavioral changes are not observed in the newborn. Bupivacaine also is approved for spinal anesthesia and is approximately four times more potent and more toxic than mepivacaine and lidocaine. It can be used with or without epinephrine.
Clinical Use
Bupivacaine hydrochloride injection is a clear, colorless solution intended for use in adults to provide local or regional anesthesia or analgesia. It is suitable for various applications, including surgical procedures, dental and oral surgery, diagnostic and therapeutic interventions, as well as obstetric procedures.
Bupivacaine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Bupivacaine hydrochloride manufacturers
- Product
- Bupivacaine hydrochloride 14252-80-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99％pure
- Supply Ability
- 1000kg
- Release date
- 2025-07-10
- Product
- Bupivacaine hydrochloride 14252-80-3
- Price
- US $10.00-20.00/kg
- Min. Order
- 1kg
- Purity
- 99.79% HPLC
- Supply Ability
- 20000tons/year
- Release date
- 2025-06-10
- Product
- Bupivacaine hydrochloride 14252-80-3
- Price
- US $5.00-0.50/KG
- Min. Order
- 1KG
- Purity
- 99% hplc
- Supply Ability
- 500TONS
- Release date
- 2025-06-05