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Bupivacaine hydrochloride

Product Name
Bupivacaine hydrochloride
CAS No.
14252-80-3
Chemical Name
Bupivacaine hydrochloride
Synonyms
Sensorcaine;ah-2250;Bupivocoine HCl;Bupivacaine HCI;Bupivacaine HCL API;marcainehydrochloride;Bupivacaine HCL (USP);BUPIVACAINE HYDROCHLORIDE;Bupivacaine Hydrochloride, USP;Bupivacaine hydrochloride,>98%
CBNumber
CB1386202
Molecular Formula
C18H28N2O.ClH
Formula Weight
324.89
MOL File
14252-80-3.mol
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Bupivacaine hydrochloride Property

Melting point:
249-2510C
storage temp. 
Refrigerator
solubility 
Soluble in water, freely soluble in alcohol.
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
InChI
InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H
InChIKey
SIEYLFHKZGLBNX-UHFFFAOYSA-N
SMILES
C1(CCCCN1CCCC)C(=O)NC1C(C)=CC=CC=1C.Cl
CAS DataBase Reference
14252-80-3(CAS DataBase Reference)
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
22-36/37/39-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
TK6125000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2933399090
Toxicity
LD50 in mice (mg/kg): 7.8 i.v., 82 s.c. (Henn, Brattsand)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H330Fatal if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P320Specific treatment is urgent (see … on this label).

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1078507
Product name
Bupivacaine hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
300mg
Price
$366
Updated
2021/12/16
TRC
Product number
B780598
Product name
Bupivacaine hydrochloride
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
B780598
Product name
Bupivacaine hydrochloride
Packaging
500mg
Price
$75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001784
Product name
BUPIVACAINE HYDROCHLORIDE
Purity
95.00%
Packaging
1G
Price
$140.7
Updated
2021/12/16
Chemenu
Product number
CM249371
Product name
1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamidehydrochloride
Purity
97%
Packaging
100g
Price
$210
Updated
2021/12/16
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Bupivacaine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

antineoplastic

Uses

Bupivacaine Hydrochloride is the salt form of Bupivacaine (B689561); is a sodium channel blocker, local anesthetic.

Definition

ChEBI: Bupivacaine hydrochloride (anhydrous) is a racemate composed of equimolar amounts of dextrobupivacaine hydrochloride and levobupivacaine hydrochloride. The monohydrate form is commonly used as a local anaesthetic. It has a role as an adrenergic antagonist, an amphiphile, an EC 3.1.1.8 (cholinesterase) inhibitor, an EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor and a local anaesthetic. It contains a levobupivacaine hydrochloride (anhydrous), a dextrobupivacaine hydrochloride (anhydrous) and a bupivacaine(1+).

brand name

Marcaine (Hospira); Sensorcaine (AstraZeneca).

Biological Functions

Bupivacaine hydrochloride (Marcaine, Sensorcaine) has particularly long action, and some nerve blocks last more than 24 hours; this is often an advantage for postoperative analgesia. Its use for epidural anesthesia in obstetrics has attracted interest because it can relieve the pain of labor at concentrations as low as 0.125% while permitting some motor activity of abdominal muscles to aid in expelling the fetus. The lower concentration minimizes the possibility of cardiac toxicity. Fetal drug concentrations remain low, and drug-induced neurobehavioral changes are not observed in the newborn. Bupivacaine also is approved for spinal anesthesia and is approximately four times more potent and more toxic than mepivacaine and lidocaine. It can be used with or without epinephrine.

Bupivacaine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Bupivacaine hydrochloride Suppliers

Shandong Mingfeng Pharmaceutical and Technology Co. Ltd
Tel
-1345456643 15315114555
Fax
QQ:1345456643
Email
1345456643@qq.com
Country
China
ProdList
248
Advantage
58
Wuhan DingCheng Biochemical Co.Ltd
Tel
027-81302558 13545255233
Email
2851686513@qq.com
Country
China
ProdList
843
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
Advantage
55
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6013
Advantage
61
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7508
Advantage
55
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9555
Advantage
66
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10194
Advantage
62
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
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View Lastest Price from Bupivacaine hydrochloride manufacturers

Wuhan Xinhao Biotechnology Co., Ltd
Product
bupivacaine hydrochloride 14252-80-3
Price
US $10.00-100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 MT/Month
Release date
2024-03-11
Wuhan Haorong Biotechnology Co.,Ltd
Product
Bupivacaine hydrochloride 14252-80-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500
Release date
2023-07-14
PNP Biotech Co. Ltd
Product
Bupivacaine hydrochloride 14252-80-3
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2022-10-19

14252-80-3, Bupivacaine hydrochlorideRelated Search:


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  • 14252-80-3
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  • CAS NO.14252-80
  • 76630-54-0
  • C18H28N2OHClH2O
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