2-Chloroveratraldehyde
- Product Name
- 2-Chloroveratraldehyde
- CAS No.
- 5417-17-4
- Chemical Name
- 2-Chloroveratraldehyde
- Synonyms
- TIMTEC-BB SBB003539;Vanillin Impurity 20;2-CHLOROVERATRALDEHYDE;LABOTEST-BB LT01147597;2-Chlorveratrumaldehyd;2‐Chlorovanillin methyl ether;2-Chloro-3,4-dimethoxybenzalde;2-CHLORO-3,4-DIMETHOXYBENZALDEHYDE;2-CHLORO-3,4-DIMETHOXYBENZALDE 98%;Benzaldehyde, 2-chloro-3,4-dimethoxy-
- CBNumber
- CB1386257
- Molecular Formula
- C9H9ClO3
- Formula Weight
- 200.62
- MOL File
- 5417-17-4.mol
2-Chloroveratraldehyde Property
- Melting point:
- 71-74 °C (lit.)
- Boiling point:
- 300.9±37.0 °C(Predicted)
- Density
- 1.245±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Sparingly), Ethyl Acetate (Slightly)
- form
- Solid
- color
- White to Pale Yellow
- Sensitive
- Air Sensitive
- BRN
- 2109344
- InChI
- InChI=1S/C9H9ClO3/c1-12-7-4-3-6(5-11)8(10)9(7)13-2/h3-5H,1-2H3
- InChIKey
- SAWHDJTZESXNMM-UHFFFAOYSA-N
- SMILES
- C(=O)C1=CC=C(OC)C(OC)=C1Cl
- CAS DataBase Reference
- 5417-17-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 566004
- Product name
- 2-Chloro-3,4-dimethoxybenzaldehyde
- Purity
- 98%
- Packaging
- 5g
- Price
- $209
- Updated
- 2023/01/07
- Product number
- C1997
- Product name
- 2-Chloro-3,4-dimethoxybenzaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $42
- Updated
- 2025/07/31
- Product number
- C1997
- Product name
- 2-Chloro-3,4-dimethoxybenzaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $96
- Updated
- 2025/07/31
- Product number
- C427660
- Product name
- 2-Chloro-3,4-dimethoxybenzaldehyde
- Packaging
- 25g
- Price
- $250
- Updated
- 2021/12/16
- Product number
- OR28781
- Product name
- 2-Chloro-3,4-dimethoxybenzaldehyde
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
2-Chloroveratraldehyde Chemical Properties,Usage,Production
Chemical Properties
beige-yellow to beige crystalline powder
Uses
2-Chloro-3,4-dimethoxybenzaldehyde is a useful reagent in the synthesis of the human TLR4 agonist euodenine A. 2-Chloro-3,4-dimethoxybenzaldehyde is also used as a reagent in the synthesis of novel 2-methoxyacylhydrazones as potent, selective PDE10A inhibitors with activity in animal models of schizophrenia.
Synthesis
37687-57-3
74-88-4
5417-17-4
Step 2 - Formation of 2-chloro-3,4-dimethoxybenzaldehyde: To a 100 mL solution of 8.03 g (43 mmol) of 2-chloro-3-hydroxy-4-methoxybenzaldehyde in acetonitrile was added 7.7 g (55 mmol) of powdered potassium carbonate, followed by the addition of 8.3 mL (0.13 mol) of iodomethane. The reaction mixture was slowly heated to reflux and stirred continuously at this temperature for 24 hours. Upon completion of the reaction, it was cooled to room temperature, the suspension was filtered and the filtrate was evaporated under vacuum to remove the solvent to give 8.5 g (42 mmol, 98% yield) of white solid. The resulting solid was confirmed to be 2-chloro-3,4-dimethoxybenzaldehyde by 1H NMR analysis.
References
[1] Synlett, 2014, vol. 25, # 20, p. 2891 - 2894
[2] Patent: US5866513, 1999, A
2-Chloroveratraldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloroveratraldehyde Suppliers
- Tel
- --
- Fax
- --
- interchim@interchim.com
- Country
- France
- ProdList
- 6302
- Advantage
- 76
View Lastest Price from 2-Chloroveratraldehyde manufacturers
- Product
- 2-Chloroveratraldehyde 5417-17-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-04
- Product
- 2-Chloroveratraldehyde 5417-17-4
- Price
- US $0.00-0.00/g
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-15
- Product
- 2-Chloroveratraldehyde 5417-17-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-31