2,5-Dimethoxybenzaldehyde
- Product Name
- 2,5-Dimethoxybenzaldehyde
- CAS No.
- 93-02-7
- Chemical Name
- 2,5-Dimethoxybenzaldehyde
- Synonyms
- Benzaldehyde, 2,5-dimethoxy-;34007;93-02--7;Benzaldehyde CRS;2,5-DiMethoxybenzaldehyde, 97% 25GR;NSC 6315;IAV-IN-4;AKOS BBS-00003162;2,5-DimethoxybenzaL;2,5-Dimethoxybenzald
- CBNumber
- CB6348890
- Molecular Formula
- C9H10O3
- Formula Weight
- 166.17
- MOL File
- 93-02-7.mol
2,5-Dimethoxybenzaldehyde Property
- Melting point:
- 46-48 °C (lit.)
- Boiling point:
- 146 °C/10 mmHg (lit.)
- Density
- 1.1708 (rough estimate)
- refractive index
- 1.5260 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- 795mg/l
- form
- Crystalline Powder, Crystals and/or Chunks
- color
- Yellow to beige
- Water Solubility
- Soluble in chloroform and methanol. Slightly soluble in water.
- Sensitive
- Air Sensitive
- BRN
- 509301
- InChI
- 1S/C9H10O3/c1-11-8-3-4-9(12-2)7(5-8)6-10/h3-6H,1-2H3
- InChIKey
- AFUKNJHPZAVHGQ-UHFFFAOYSA-N
- SMILES
- [H]C(=O)c1cc(OC)ccc1OC
- LogP
- 1.910
- CAS DataBase Reference
- 93-02-7(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzaldehyde, 2,5-dimethoxy-(93-02-7)
- EPA Substance Registry System
- Benzaldehyde, 2,5-dimethoxy- (93-02-7)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-43
- Safety Statements
- 26-36/37/39-24/25-36
- WGK Germany
- 2
- RTECS
- CU5740500
- Hazard Note
- Irritant
- TSCA
- TSCA listed
- HS Code
- 29124900
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Resp. Sens. 1
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D130605
- Product name
- 2,5-Dimethoxybenzaldehyde
- Purity
- 99%
- Packaging
- 25g
- Price
- $57.5
- Updated
- 2026/03/19
- Product number
- D130605
- Product name
- 2,5-Dimethoxybenzaldehyde
- Purity
- 99%
- Packaging
- 100g
- Price
- $130
- Updated
- 2026/03/19
- Product number
- D1111
- Product name
- 2,5-Dimethoxybenzaldehyde
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $57
- Updated
- 2026/03/19
- Product number
- D1111
- Product name
- 2,5-Dimethoxybenzaldehyde
- Purity
- >97.0%(GC)
- Packaging
- 250g
- Price
- $389
- Updated
- 2021/12/16
- Product number
- D460855
- Product name
- 2,5-Dimethoxybenzaldehyde
- Packaging
- 10g
- Price
- $65
- Updated
- 2021/12/16
2,5-Dimethoxybenzaldehyde Chemical Properties,Usage,Production
Chemical Properties
yellow crystalline solid
Uses
2,5-Dimethoxybenzaldehyde is used in the preparation of 2,5-dimethoxyphenethylamine, which is utilized to prepare psychoactive drugs such as 2,5-dimethoxy-4-bromophenethylamine, 2,5-dimethoxy-4-iodophenethylamine and 4-Chloro-2,5-dimethoxy-phenethylamine. It acts as an intermediate in organic synthesis.
Application
2,5-Dimethoxybenzaldehyde, also known as 2C-H, is an organic compound and a benzaldehyde derivative. It can be used to produce 2,5-dimethoxyphenethylamine. 2C-H is also used to produce many other substituted phenethylamines such as 2C-B, 2C-I and 2C-C.
Definition
ChEBI: 2,5-dimethoxy-Benzaldehyde is a dimethoxybenzene.
Preparation
2,5-Dimethoxybenzaldehyde synthesis: Anethole is oxidized to anisaldehyde , which after isolation is subjected to a BaeyerVilliger oxidation reaction with performic or peracetic acid. The O-formyl-4-methoxyphenol obtained this way is hydrolyzed . 4-Methoxyphenol is subsequently formylated using the Reimer-Tiemann method and the obtained 2-hydroxy-5-methoxybenzaldehyde is methylated with dimethylsulfate to 2,5-dimethoxybenzaldehyde.
Synthesis
The synthesis of 2,5-dimethoxybenzaldehyde (2,5-DMBA) is mainly achieved through several well-established chemical methods, typically using readily available precursors as starting materials. A common industrial method is the formylation of 1,4-dimethoxybenzene (hydroquinone dimethyl ether), usually using the Vilsmeier-Haack reaction with reagents including N,N-dimethylformamide and phosphorus oxychloride; or using a Friedel-Crafts-type reaction, starting with 1,1-dichlorodimethyl ether, directly introducing the aldehyde group onto the activated aromatic ring. In addition, 2,5-DMBA can also be prepared by oxidizing the methyl group of 2,5-dimethoxytoluene, or through a multi-step reaction, starting with p-methoxyphenol, first undergoing a Reimer-Tiemann reaction to generate 2-hydroxy-5-methoxybenzaldehyde, and finally methoxylating it with dimethyl sulfate. These methods offer flexibility in terms of scale and precursor availability, making 2,5-DMBA a versatile intermediate for the synthesis of a wide range of fine chemicals, particularly psychoactive compounds such as 2C-H.
2,5-Dimethoxybenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,5-Dimethoxybenzaldehyde manufacturers
- Product
- 2,5-Dimethoxybenzaldehyde 93-02-7
- Price
- US $280.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 99999
- Release date
- 2026-04-05
- Product
- 2,5-Dimethoxybenzaldehyde 93-02-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100tons
- Release date
- 2025-11-20
- Product
- 2,5-Dimethoxybenzaldehyde 93-02-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2025-09-12