KHELLIN
- Product Name
- KHELLIN
- CAS No.
- 82-02-0
- Chemical Name
- KHELLIN
- Synonyms
- VISNAGIN;eskel;norkel;KHELIN;keloid;ammivin;KHELLIN;chellin;kelamin;kelicor
- CBNumber
- CB5269554
- Molecular Formula
- C14H12O5
- Formula Weight
- 260.24
- MOL File
- 82-02-0.mol
KHELLIN Property
- Melting point:
- 150154°C
- Boiling point:
- 180200°C0.05mm Hg
- Density
- 1.1954 (rough estimate)
- refractive index
- 1.4560 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- crystalline
- color
- light yellow
- Water Solubility
- 247.2g/L(25 ºC)
- Merck
- 14,5309
- BRN
- 263185
- LogP
- 1.770 (est)
- EPA Substance Registry System
- Khellin (82-02-0)
Safety
- Hazard Codes
- T
- Risk Statements
- 25-38-36/37/38-23/24/25
- Safety Statements
- 36/37/39-45-26
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- LV1050000
- HS Code
- 2932.99.7000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Toxicity
- LD50 in mice, rats (mg/kg): 30.6, 34.4 i.v.; 50.8, 68.8 orally (Busch)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PHL89481
- Product name
- Khellin
- Purity
- phyproof? Reference Substance
- Packaging
- 100MG
- Price
- $358
- Updated
- 2024/03/01
- Product number
- 60730
- Product name
- Khellin
- Purity
- for microscopy
- Packaging
- 10g
- Price
- $234
- Updated
- 2024/03/01
- Product number
- 00899
- Product name
- Khellin
- Purity
- analytical standard
- Packaging
- 100MG
- Price
- $244
- Updated
- 2024/03/01
- Product number
- K0039
- Product name
- Khellin
- Purity
- >95.0%(GC)
- Packaging
- 5g
- Price
- $155
- Updated
- 2024/03/01
- Product number
- K0039
- Product name
- Khellin
- Purity
- >95.0%(GC)
- Packaging
- 25g
- Price
- $497
- Updated
- 2024/03/01
KHELLIN Chemical Properties,Usage,Production
Uses
vasodilator (coronary), photosensitizer
Uses
Khellin has been used as a reference standard for supercritical fluid extraction of khellin from Ammi visnaga L. fruits to understand the various medicinal effects of γ-Pyrones by reversed phase HPLC method.
Definition
ChEBI: Khellin is a furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator. It has a role as a vasodilator agent, a bronchodilator agent, an anti-asthmatic agent and a cardiovascular drug. It is an organic heterotricyclic compound, an oxacycle and a furanochromone. It is functionally related to a 5H-furo[3,2-g]chromen-5-one.
brand name
Ammivin (Marion Merrell Dow); Khelloyd (Hoechst-Roussel).
Synthesis Reference(s)
Journal of Medicinal Chemistry, 26, p. 1672, 1983 DOI: 10.1021/jm00366a002
General Description
Khellin, is reported to be an efficient drug for treating vitiligo when combined with ultraviolet A irradiation.
Purification Methods
Crystallise khellin from H2O, MeOH, pet ether or Et2O. The hydrochloride has m 98o(dec) (from EtOH/HCl). [Beilstein 19 II 236, 19 III/IV 2816, 19/6 V 320.]
KHELLIN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from KHELLIN manufacturers
- Product
- Khellin 82-02-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-11