ChemicalBook > CAS DataBase List > VISNAGIN

VISNAGIN

Product Name
VISNAGIN
CAS No.
82-57-5
Chemical Name
VISNAGIN
Synonyms
VISNAGIN;visnagine;visnagidin;VISNAGIN(P);VISNAGIN(RG);Metofuroxime;desmethoxykhellin;VISNAGIN USP/EP/BP;LABOTEST-BB LT00441024;4-Methoxy-7-methyl-5H-furo
CBNumber
CB5434295
Molecular Formula
C13H10O4
Formula Weight
230.22
MOL File
82-57-5.mol
More
Less

VISNAGIN Property

Melting point:
139-142 °C
Boiling point:
292.2°C (rough estimate)
Density 
1.1302 (rough estimate)
refractive index 
1.4300 (estimate)
storage temp. 
2-8°C
solubility 
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form 
Fine Crystalline Powder
color 
Beige
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
LogP
2.260 (est)
CAS DataBase Reference
82-57-5(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
RTECS 
LV1420000
HS Code 
29162000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T341649
Product name
VISNAGIN
Purity
Aldrich
Packaging
1g
Price
$179
Updated
2024/03/01
TRC
Product number
V675008
Product name
Visnagin
Packaging
500mg
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FV42573
Product name
Visnagin
Packaging
5G
Price
$100
Updated
2021/12/16
Biorbyt Ltd
Product number
orb546235
Product name
Visnagin
Purity
>98%
Packaging
25mg
Price
$127.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FV42573
Product name
Visnagin
Packaging
10g
Price
$175
Updated
2021/12/16
More
Less

VISNAGIN Chemical Properties,Usage,Production

Description

Visnagin (82-57-5) is a natural product isolated from the plant Ammi visnaga.? It displays protective effects against doxorubicin-induced cardiomyopathy via inhibition of mitochondrial malate dehydrogenase resulting in a decrease in cardiomyocyte apoptosis.1

Chemical Properties

BEIGE FINE CRYSTALLINE POWDER

Uses

antiinflammatory, neuroprotective

Definition

ChEBI: Visnagin is a furanochromone that is furo[3,2-g]chromen-5-one which is substituted at positions 4 and 7 by methoxy and methyl groups, respectively. Found in the toothpick-plant, Ammi visnaga. It has a role as a phytotoxin, an EC 1.1.1.37 (malate dehydrogenase) inhibitor, a vasodilator agent, an antihypertensive agent, an anti-inflammatory agent and a plant metabolite. It is a furanochromone, an aromatic ether and a polyketide. It is functionally related to a 5H-furo[3,2-g]chromen-5-one.

Purification Methods

Crystallise visnagin from water. It is soluble in CHCl3 but slightly soluble in EtOH. [Aneja et al. Tetrahedron 3 230 1958, Beilstein 19 III/IV 2640.]

References

1) Liu et al. (2014), Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase; Sci. Transl. Med. 6 266ra170

VISNAGIN Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

VISNAGIN Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7887
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58

82-57-5, VISNAGINRelated Search:


  • 5-METHOXY-2-METHYL-FURANOCHROMONE
  • 4-METHOXY-7-METHYL-5H-FURO[3,2-G][1]-BENZOPYRAN-5-ONE
  • 4-METHOXY-7-METHYL-FURO[3,2-G]CHROMEN-5-ONE
  • LABOTEST-BB LT00441024
  • VISNAGIN
  • 2-g)(1)benzopyran-5-one,4-methoxy-7-methyl-5h-furo(
  • desmethoxykhellin
  • visnagidin
  • visnagine
  • VISNAGIN(RG)
  • 4-METHOXY-7-METHYL-5H-FURO[3,2-G][1]-BENZOPYRAN-5-ONE 97%
  • 4-METHOXY-7-METHYL-5H-FURO3,2-Ga1a-BENZOPYRAN-5-ONE, 97%
  • 4-Methoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one,97%
  • 4-Methoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-oneVisnagin
  • 4-Methoxy-7-methyl-5H-furo
  • VISNAGIN(P)
  • Metofuroxime
  • 5H-Furo[3,2-g][1]benzopyran-5-one, 4-methoxy-7-methyl-
  • VISNAGIN USP/EP/BP
  • 82-57-5
  • Heterocyclic Building Blocks
  • Coumarins
  • Building Blocks
  • Chromones