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VISNAGIN

Product Name
VISNAGIN
CAS No.
82-57-5
Chemical Name
VISNAGIN
Synonyms
VISNAGIN;visnagine;visnagidin;VISNAGIN(P);VISNAGIN(RG);Metofuroxime;desmethoxykhellin;VISNAGIN USP/EP/BP;LABOTEST-BB LT00441024;4-Methoxy-7-methyl-5H-furo
CBNumber
CB5434295
Molecular Formula
C13H10O4
Formula Weight
230.22
MOL File
82-57-5.mol
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VISNAGIN Property

Melting point:
139-142 °C
Boiling point:
292.2°C (rough estimate)
Density 
1.1302 (rough estimate)
refractive index 
1.4300 (estimate)
storage temp. 
2-8°C
solubility 
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form 
Fine Crystalline Powder
color 
Beige
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
LogP
2.260 (est)
CAS DataBase Reference
82-57-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
RTECS 
LV1420000
HS Code 
29162000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T341649
Product name
VISNAGIN
Purity
Aldrich
Packaging
1g
Price
$179
Updated
2024/03/01
TRC
Product number
V675008
Product name
Visnagin
Packaging
500mg
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FV42573
Product name
Visnagin
Packaging
5G
Price
$100
Updated
2021/12/16
Biorbyt Ltd
Product number
orb546235
Product name
Visnagin
Purity
>98%
Packaging
25mg
Price
$127.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FV42573
Product name
Visnagin
Packaging
10g
Price
$175
Updated
2021/12/16
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VISNAGIN Chemical Properties,Usage,Production

Description

Visnagin (82-57-5) is a natural product isolated from the plant Ammi visnaga.? It displays protective effects against doxorubicin-induced cardiomyopathy via inhibition of mitochondrial malate dehydrogenase resulting in a decrease in cardiomyocyte apoptosis.1

Chemical Properties

BEIGE FINE CRYSTALLINE POWDER

Uses

antiinflammatory, neuroprotective

Definition

ChEBI: Visnagin is a furanochromone that is furo[3,2-g]chromen-5-one which is substituted at positions 4 and 7 by methoxy and methyl groups, respectively. Found in the toothpick-plant, Ammi visnaga. It has a role as a phytotoxin, an EC 1.1.1.37 (malate dehydrogenase) inhibitor, a vasodilator agent, an antihypertensive agent, an anti-inflammatory agent and a plant metabolite. It is a furanochromone, an aromatic ether and a polyketide. It is functionally related to a 5H-furo[3,2-g]chromen-5-one.

Purification Methods

Crystallise visnagin from water. It is soluble in CHCl3 but slightly soluble in EtOH. [Aneja et al. Tetrahedron 3 230 1958, Beilstein 19 III/IV 2640.]

References

1) Liu et al. (2014), Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase; Sci. Transl. Med. 6 266ra170

VISNAGIN Preparation Products And Raw materials

Raw materials

Preparation Products

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VISNAGIN Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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62
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
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61
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
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65
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
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75
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
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Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
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China
ProdList
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Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
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China
ProdList
8065
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Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
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028-81705658
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3003855609@qq.com
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China
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7887
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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0510-85629785 18013409632
Fax
051085625359
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sales@reading-chemicals.com
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China
ProdList
15178
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