2,5-Dimethoxybenzaldehyde

Product Name: 2,5-Dimethoxybenzaldehyde
CAS No.: 93-02-7
Chemical Name: 2,5-Dimethoxybenzaldehyde
Synonyms: Benzaldehyde, 2,5-dimethoxy-;34007;93-02--7;Benzaldehyde CRS;2,5-DiMethoxybenzaldehyde, 97% 25GR;NSC 6315;AKOS BBS-00003162;2,5-DimethoxybenzaL;2,5-Dimethoxybenzald;5-DiMethoxy benzaldehyde
CBNumber: CB6348890
Molecular Formula: C9H10O3
Formula Weight: 166.17
MOL File: 93-02-7.mol

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2,5-Dimethoxybenzaldehyde Property

Melting point:: 46-48 °C (lit.)
Boiling point:: 146 °C/10 mmHg (lit.)
Density: 1.1708 (rough estimate)
refractive index: 1.5260 (estimate)
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: 795mg/l
form: Crystalline Powder, Crystals and/or Chunks
color: Yellow to beige
Water Solubility: Soluble in chloroform and methanol. Slightly soluble in water.
Sensitive: Air Sensitive
BRN: 509301
InChIKey: AFUKNJHPZAVHGQ-UHFFFAOYSA-N
LogP: 1.910
CAS DataBase Reference: 93-02-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzaldehyde, 2,5-dimethoxy-(93-02-7)
EPA Substance Registry System: Benzaldehyde, 2,5-dimethoxy- (93-02-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-43
Safety Statements: 26-36/37/39-24/25-36
WGK Germany: 2
RTECS: CU5740500
Hazard Note: Irritant
TSCA: Yes
HS Code: 29124900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D130605
Product name: 2,5-Dimethoxybenzaldehyde
Purity: 99%
Packaging: 25g
Price: $54
Updated: 2025/07/31

Sigma-Aldrich

Product number: D130605
Product name: 2,5-Dimethoxybenzaldehyde
Purity: 99%
Packaging: 100g
Price: $115.9
Updated: 2025/07/31

TCI Chemical

Product number: D1111
Product name: 2,5-Dimethoxybenzaldehyde
Purity: >97.0%(GC)
Packaging: 25g
Price: $57
Updated: 2025/07/31

TCI Chemical

Product number: D1111
Product name: 2,5-Dimethoxybenzaldehyde
Purity: >97.0%(GC)
Packaging: 250g
Price: $389
Updated: 2021/12/16

TRC

Product number: D460855
Product name: 2,5-Dimethoxybenzaldehyde
Packaging: 10g
Price: $65
Updated: 2021/12/16

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2,5-Dimethoxybenzaldehyde Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline solid

Uses

2,5-Dimethoxybenzaldehyde is used in the preparation of 2,5-dimethoxyphenethylamine, which is utilized to prepare psychoactive drugs such as 2,5-dimethoxy-4-bromophenethylamine, 2,5-dimethoxy-4-iodophenethylamine and 4-Chloro-2,5-dimethoxy-phenethylamine. It acts as an intermediate in organic synthesis.

Application

2,5-Dimethoxybenzaldehyde, also known as 2C-H, is an organic compound and a benzaldehyde derivative. It can be used to produce 2,5-dimethoxyphenethylamine. 2C-H is also used to produce many other substituted phenethylamines such as 2C-B, 2C-I and 2C-C.

Definition

ChEBI: 2,5-dimethoxy-Benzaldehyde is a dimethoxybenzene.

Preparation

2,5-Dimethoxybenzaldehyde synthesis: Anethole is oxidized to anisaldehyde , which after isolation is subjected to a BaeyerVilliger oxidation reaction with performic or peracetic acid. The O-formyl-4-methoxyphenol obtained this way is hydrolyzed . 4-Methoxyphenol is subsequently formylated using the Reimer-Tiemann method and the obtained 2-hydroxy-5-methoxybenzaldehyde is methylated with dimethylsulfate to 2,5-dimethoxybenzaldehyde.

Synthesis

The synthesis of 2,5-dimethoxybenzaldehyde (2,5-DMBA) is mainly achieved through several well-established chemical methods, typically using readily available precursors as starting materials. A common industrial method is the formylation of 1,4-dimethoxybenzene (hydroquinone dimethyl ether), usually using the Vilsmeier-Haack reaction with reagents including N,N-dimethylformamide and phosphorus oxychloride; or using a Friedel-Crafts-type reaction, starting with 1,1-dichlorodimethyl ether, directly introducing the aldehyde group onto the activated aromatic ring. In addition, 2,5-DMBA can also be prepared by oxidizing the methyl group of 2,5-dimethoxytoluene, or through a multi-step reaction, starting with p-methoxyphenol, first undergoing a Reimer-Tiemann reaction to generate 2-hydroxy-5-methoxybenzaldehyde, and finally methoxylating it with dimethyl sulfate. These methods offer flexibility in terms of scale and precursor availability, making 2,5-DMBA a versatile intermediate for the synthesis of a wide range of fine chemicals, particularly psychoactive compounds such as 2C-H.

2,5-Dimethoxybenzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

2,5-Dimethoxybenzylamine

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2,5-Dimethoxybenzaldehyde Suppliers

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View Lastest Price from 2,5-Dimethoxybenzaldehyde manufacturers

Shandong Vital Biotechnology Co., Ltd.

Product: 2,5-Dimethoxybenzaldehyde 93-02-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100tons
Release date: 2025-11-20

Shaanxi Dideu Medichem Co. Ltd

Product: 2,5-Dimethoxybenzaldehyde 93-02-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2025-09-12

RongNa Biotechnology Co.,Ltd

Product: 2,5-Dimethoxybenzaldehyde 93-02-7
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20 tons
Release date: 2025-05-04

93-02-7, 2,5-DimethoxybenzaldehydeRelated Search:

1,1-Dimethoxyethane Benzaldehyde p-Anisaldehyde o-Anisaldehyde 3-(METHOXYMETHOXY)BENZALDEHYDE 4-Dimethylaminobenzaldehyde 3-Methoxybenzaldehyde Diphenyldimethoxysilane Dimethoxymethane 2,4-Dimethoxybenzaldehyde 2',5'-Dimethoxyacetophenone 2,5-DIMETHOXYBENZOYL CHLORIDE 2,4,5-Trimethoxybenzoic acid Veratraldehyde 2,3-DIMETHOXYBENZALDEHYDE 2,6-Dimethoxybenzaldehyde KHELLIN 3,5-Dimethoxybenzaldehyde ,98%

2,5-Dimethoxybenzaldehyde,97%

2,5-Dimethoxybenzald

5-DiMethoxy benzaldehyde

2,5-DiMethoxybenzaldehyde, 97% 25GR

NSC 6315

93-02--7

2,5-Dimethoxybenzaldehyde Vetec(TM) reagent grade, 98%

2,5-DIMETHOXYBENZALDEHYDE

AKOS BBS-00003162

Benzaldehyde, 2,5-dimethoxy-

2,5-Dimethoxybenzaldehyde, 98+%

34007

2,5-dimethoxy-benzaldehyd

Benzaldehyde CRS

2,5-Dimethoxybenzaldehyde &gt

2,5-DimethoxybenzaL

Methoxamine Impurity 2 (2,5-Dimethoxybenzaldehyde)

Supply 2,5-Dimethoxybenzaldehyde

2,5 -Dimethoxybenzaldehyde 2

gentisic aldehyde dimethyl ether

CAS 93-02-7 2, 5-Dimethoxybenzaldehyde 2, 5- (MeO) 2phcho

2,5-Dimethoxybenzaldehyde (2,5-DMB) pure, 98%

93-02-7

1993-02-7

1993-2-7

1993-02-07

92-02-7

ALDEHYDE

Organic Building Blocks

Aldehydes

C9

Carbonyl Compounds

Building Blocks

Carbonyl Compounds

Chemical Synthesis

Organic Building Blocks

Aromatics

FINE Chemical & INTERMEDIATES

BUILDING BLOCKS

Benzaldehyde

Adehydes, Acetals & Ketones

Anisoles, Alkyloxy Compounds & Phenylacetates

Aldehydes

C9

Carbonyl Compounds

93-02-7