ChemicalBook > CAS DataBase List > Adrenalone

Adrenalone

Product Name
Adrenalone
CAS No.
99-45-6
Chemical Name
Adrenalone
Synonyms
u2134;adrenon;stypnon;chemosan;adrenone;haemodan;kephrine;ketogaze;remestyp;stryphnon
CBNumber
CB1388796
Molecular Formula
C9H11NO3
Formula Weight
181.19
MOL File
99-45-6.mol
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Adrenalone Property

Melting point:
235.5°C (rough estimate)
Boiling point:
314.29°C (rough estimate)
Density 
1.2375 (rough estimate)
refractive index 
1.5270 (estimate)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Aqueous Acid (Slightly)
form 
Solid
pka
7.32±0.20(Predicted)
color 
Pale Yellow to Light Yellow
Stability:
Hygroscopic
InChI
InChI=1S/C9H11NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,10-12H,5H2,1H3
InChIKey
PZMVOUYYNKPMSI-UHFFFAOYSA-N
SMILES
C(=O)(C1=CC=C(O)C(O)=C1)CNC
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A305095
Product name
Adrenalone
Packaging
10g
Price
$1185
Updated
2021/12/16
AK Scientific
Product number
Q759
Product name
Adrenalone
Packaging
100mg
Price
$212
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BIO0000126
Product name
ADRENALONE
Purity
95.00%
Packaging
1G
Price
$329.7
Updated
2021/12/16
AK Scientific
Product number
Q759
Product name
Adrenalone
Packaging
1g
Price
$455
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
42795
Product name
Adrenalone
Packaging
1g
Price
$875
Updated
2021/12/16
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Adrenalone Chemical Properties,Usage,Production

Chemical Properties

Needle-shaped crystal. Decomposition temperature 235-236 ℃, slightly soluble in water, alcohol, ether. Its hydrochloride, melting point 243 ° C, soluble in water, soluble in ethanol, insoluble in ether.

Originator

Adrenalone ,Yick-Vic Chemicals and Pharmaceuticals (HK) Ltd.

Uses

Adrenergic (ophthalmic).

Uses

Adrenalone is a ketone derivative of Epinephrine (E588585) and a potential dopamine β oxidase inhibitor.

Definition

ChEBI: Adrenalone is an aromatic ketone.

Preparation

Preparation by reaction of excess 33% aqueous methylamine with 3,4-dihydroxy-a-chloroacetophenone.

Manufacturing Process

To a suspension of 1 part ω-chloro-3,4-dihydroxyacetophenone (prerared from chloroacetyl chloride and benzcatechole, see J. Russ. Phys. Chem. Ges., 25, 154) was added dropwise 1 part 60% solution of methylamine. Immediately was formed a residue of the salt of methylamine and ω-chloro-3,4- dihydroxyacetophenone. The dissolution of the salt was carried out by heating of the mixture. Then the salt was converted in crude 3,4-dihydroxy-α- methylaminoacetophenone. The product was dissolved in dilute hydrochloric acid. To this solution was added dropwise aqueous ammonium solution to prepare light yellow crystal of 3,4-dihydroxy-α-methylaminoacetophenone. The base and the hydrochloride of 3,4-dihydroxy-α-methylaminoacetophenone decomposed at temperature near 230°C and 240°C respectively.

Therapeutic Function

Hemostatic, Sympathomimetic, Vasoconstrictor

Adrenalone Preparation Products And Raw materials

Raw materials

Catechol 2-Chloro-3',4'-dihydroxyacetophenone

Preparation Products

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Adrenalone Suppliers

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View Lastest Price from Adrenalone manufacturers

Dideu Industries Group Limited
Product
Adrenalone 99-45-6
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-05
Career Henan Chemical Co
Product
Adrenalone 99-45-6
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1kg
Release date
2019-12-30

99-45-6, AdrenaloneRelated Search:

L-PICEIN 3'-DIMETHYLAMINOACETOPHENONE Corticotropin 3,4-Dihydroxyacetophenone 4-Aminoacetophenone 2,4-Dihydroxyacetophenone 2-Aminoacetophenone 2-Aminoecetophenone 2'-Methylacetophenone Phenylhydrazine 3-Aminoacetophenone PHENYL VALERATE CORTISONE 4'-Hydroxyacetophenone 3'-(Trifluoromethyl)acetophenone L(-)-Epinephrine Adrenalone hydrochloride monohydrate, 98+%,ADRENALONE HYDROCHLORIDE 1-HYDRATE,ADRENALONE HCL,ADRENALONE HYDROCHLORIDE TRIS EDTA ACETATE BUFFER, 10X, DNASE, RNASE AND PROTEASE FREE, PH 8.3, FOR MOLECULAR BIOLOGY

  • ADRENALONE
  • AKOS NCG-0050
  • 1-(3,4-dihydroxyphenyl)-2-(methylamino)-ethanon
  • 3,4-dihydroxy-alpha-methylaminoacetophenone
  • 3’,4’-dihydroxy-2-(methylamino)-acetophenon
  • 3’,4’-dihydroxy-2-(methylamino)acetophenone
  • 4-methylaminoacetocatechol
  • 4-methylaminoacetopyrocatechol
  • adrenon
  • adrenone
  • chemosan
  • haemodan
  • kephrine
  • 1-(3,4-DIHYDROXY-PHENYL)-2-METHYLAMINO-ETHANONE
  • ketogaze
  • methaminoacetocatechol
  • remestyp
  • stryphnon
  • stryphnone
  • styphnone
  • stypnon
  • u2134
  • 3,4-DIHYDROXY-A-METHYLAMINOACETOPHENONE
  • NSC 243611
  • Dipivefrine EP Impurity B
  • Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-
  • Adrenalone USP/EP/BP
  • 99-45-6 Adrenalone
  • 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanone (adrenalone)
  • c .?1-(3,4-d i h yd roxyph e nyl)-2-(me th yla mi no)e th a none (a d re na lone )
  • Adrenaline EP Impurity C（Carbazochrome Sodium Sulfonate Impurity 3）
  • Dipivefrine EP Impurity B HCl
  • Dipivefrine Hydrochloride Impurity 2 (Dipivefrine Hydrochloride EP Impurity B)
  • Dipivefrine Hydrochloride Impurity 2
  • 99-45-6
  • Pharmaceutical Intermediates