ChemicalBook > CAS DataBase List > 3'-(Trifluoromethyl)acetophenone

3'-(Trifluoromethyl)acetophenone

Product Name
3'-(Trifluoromethyl)acetophenone
CAS No.
349-76-8
Chemical Name
3'-(Trifluoromethyl)acetophenone
Synonyms
3-(TRIFLUOROMETHYL)ACETOPHENONE;3-ACETYLBENZOFLUORIDE;3-Trifluoroacetophenone;3-ACETYLBENZOTRIFLUORIDE;3-trifluoromethylhypnone;3-Trifludromethylacetophen;3-trifluoromethylphenacetone;3'-(Trifluoromethyl)acetophe;3-Trifluorometylacetophenone;3-Trifludromethylacetophenone
CBNumber
CB7290680
Molecular Formula
C9H7F3O
Formula Weight
188.15
MOL File
349-76-8.mol
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3'-(Trifluoromethyl)acetophenone Property

Boiling point:
198-200 °C(lit.)
Density 
1.235 g/mL at 25 °C(lit.)
vapor pressure 
35Pa at 25℃
refractive index 
n20/D 1.4611(lit.)
Flash point:
183 °F
storage temp. 
Sealed in dry,Room Temperature
form 
clear liquid
color 
Colorless to Red to Green
Specific Gravity
1.235
Water Solubility 
620mg/L at 25℃
BRN 
640151
InChI
1S/C9H7F3O/c1-6(13)7-3-2-4-8(5-7)9(10,11)12/h2-5H,1H3
InChIKey
ABXGMGUHGLQMAW-UHFFFAOYSA-N
SMILES
CC(=O)c1cccc(c1)C(F)(F)F
LogP
2.55 at 25℃
CAS DataBase Reference
349-76-8(CAS DataBase Reference)
NIST Chemistry Reference
3-CF3-C6H4-COCH3(349-76-8)
EPA Substance Registry System
Ethanone, 1-[3-(trifluoromethyl)phenyl]- (349-76-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
1
TSCA 
TSCA listed
HazardClass 
IRRITANT
HS Code 
29147090
Storage Class
10 - Combustible liquids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
233161
Product name
3′-(Trifluoromethyl)acetophenone
Purity
99%
Packaging
5g
Price
$37.9
Updated
2023/01/07
Sigma-Aldrich
Product number
233161
Product name
3′-(Trifluoromethyl)acetophenone
Purity
99%
Packaging
25g
Price
$107
Updated
2023/01/07
TCI Chemical
Product number
T1546
Product name
3'-(Trifluoromethyl)acetophenone
Purity
>97.0%(GC)
Packaging
5g
Price
$22
Updated
2025/07/31
TCI Chemical
Product number
T1546
Product name
3'-(Trifluoromethyl)acetophenone
Purity
>97.0%(GC)
Packaging
25g
Price
$86
Updated
2025/07/31
TRC
Product number
T796963
Product name
3''-​(Trifluoromethyl)​acetophenone
Packaging
500mg
Price
$45
Updated
2021/12/16
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3'-(Trifluoromethyl)acetophenone Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID

Uses

3''-?(Trifluoromethyl)?acetophenone is a reagent used in the stabilization of endosomal-toll-like receptor TRL8 creating a sort of inhibitory activity.

General Description

Asymmetric catalytic addition of ethyl groups to 3′-(trifluoromethyl)acetophenone catalyzed by ligands derived from trans-1,2-diaminocyclohexane and camphor sulfonyl chloride has been reported. Phenylation of 3′-(trifluoromethyl)acetophenone in the presence of dihydroxy bis(sulfonamide) ligand (enantioselective catalyst), titanium tetraisopropoxide and diphenylzinc has been investigated.

3'-(Trifluoromethyl)acetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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3'-(Trifluoromethyl)acetophenone Suppliers

Fuxin Simai Chemical Technology Co., Ltd.
Tel
13841818553
Email
929964679@qq.com
Country
China
ProdList
446
Advantage
58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd.
Tel
0513-82104991 18912868322
Fax
QQ1907456386
Email
sales11@btcpharm.com
Country
China
ProdList
1301
Advantage
58
Henan Lingbei Biotechnology Co., Ltd
Tel
86-18539896799 18539896799
Email
71889632@qq.com
Country
China
ProdList
183
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Liaoning Tianhua Chemical Co., Ltd.
Tel
0418-6530555 2855550
Fax
+86-418-6502885
Country
China
ProdList
338
Advantage
69
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9401
Advantage
55
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View Lastest Price from 3'-(Trifluoromethyl)acetophenone manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
3′-(Trifluoromethyl)acetophenone 349-76-8
Price
US $3.00-9.00/KG
Min. Order
0.01KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-06-21
Great Innovation (Shanghai) Pharma Co., Ltd.,
Product
3'-(Trifluoromethyl)acetophenone 349-76-8
Price
US $4190.00/kg
Min. Order
1000kg
Purity
99%
Supply Ability
20T per month
Release date
2024-08-01
Shaanxi Dideu Medichem Co. Ltd
Product
3'-(Trifluoromethyl)acetophenone 349-76-8
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%
Supply Ability
2000tons
Release date
2020-01-16

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