Benzyl 2-bromoethyl ether
- Product Name
- Benzyl 2-bromoethyl ether
- CAS No.
- 1462-37-9
- Chemical Name
- Benzyl 2-bromoethyl ether
- Synonyms
- Benzyloxyethyl Bromide;UMECLIDIUM intermediate;2-Bromoethylbenzyl ether;2- benzyloxy bromoethane;Benzyl 2-bromoethyl ethe;2-BENZYLOXY-1-BROMOETHANE;1-BENZYLOXY-2-BROMOETHANE;1-BROMO-2-BENZYLOXYETHANE;BENZYL 2-BROMOETHYL ETHER;bromoethyl-2-benzyl ether
- CBNumber
- CB1393800
- Molecular Formula
- C9H11BrO
- Formula Weight
- 215.09
- MOL File
- 1462-37-9.mol
Benzyl 2-bromoethyl ether Property
- Boiling point:
- 254 °C(lit.)
- Density
- 1.36 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.541(lit.)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- liquid
- color
- colorless to yellow
- Water Solubility
- Slightly soluble in water
- InChI
- InChI=1S/C9H11BrO/c10-6-7-11-8-9-4-2-1-3-5-9/h1-5H,6-8H2
- InChIKey
- FWOHDAGPWDEWIB-UHFFFAOYSA-N
- SMILES
- C1(COCCBr)=CC=CC=C1
- CAS DataBase Reference
- 1462-37-9
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 474819
- Product name
- Benzyl 2-bromoethyl ether
- Purity
- 97%
- Packaging
- 1g
- Price
- $25.46
- Updated
- 2025/07/31
- Product number
- 474819
- Product name
- Benzyl 2-bromoethyl ether
- Purity
- 97%
- Packaging
- 10g
- Price
- $245.1
- Updated
- 2025/07/31
- Product number
- B2817
- Product name
- Benzyl 2-Bromoethyl Ether
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $34
- Updated
- 2025/07/31
- Product number
- B2817
- Product name
- Benzyl 2-Bromoethyl Ether
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $134
- Updated
- 2025/07/31
- Product number
- B684680
- Product name
- [(2-Bromoethyloxy)methyl]benzene
- Packaging
- 5G
- Price
- $95
- Updated
- 2021/12/16
Benzyl 2-bromoethyl ether Chemical Properties,Usage,Production
Chemical Properties
Clear colorless to pale yellow liquid
Uses
Benzyl 2-broMoethyl ether is a reactant used in the preparation of muscarinic antagonist.
Uses
Alkylation reagent for synthesis of a macrocyclic antifungal antibiotic. Building block used to prepare a copper phthalocyanine discotic liquid crystal.
General Description
Benzyl 2-bromoethyl ether is an organic building block. Its enthalpy of vaporization at boiling point (527.15K) has been reported to be 46.499kjoule/mol.
Synthesis
622-08-2
1462-37-9
Step 2: To a stirred solution of 2-benzyloxyethanol (17.0 g, 111.884 mmol) and triphenylphosphine (35.0 g, 134.21 mmol) in dichloromethane (170 mL) was slowly added N-bromosuccinimide (23.88 g, 134.21 mmol) in batches at a temperature between -10°C and -5°C, keeping the reaction temperature at -10 °C to -5 °C. After the addition was completed, the reaction mixture was continued to be stirred at room temperature for 1 hour until complete consumption of the feedstock was confirmed by thin layer chromatography (TLC) analysis. Upon completion of the reaction, the mixture was concentrated and the crude product was purified by column chromatography (CC) using a petroleum ether solution of 5% ethyl acetate as eluent to afford benzyl 2-bromoethyl ether (13.5 g, 56.2% yield) as a light yellow liquid (TLC conditions: petroleum ether solution of 30% ethyl acetate; Rf value: 0.7).
References
Martin W. M. Fijten.; Claudia Haensch.; Bart M. van Lankvelt.; Richard Hoogenboom.; Ulrich S. Schubert. Clickable Poly(2-Oxazoline)s as Versatile Building Blocks. Macromolecular Chemistry and Physics. 2008, 209 (18),1887-1895. DOI:10.1002/MACP.200800226
Britt A. Minch.; Wei Xia.; Carrie L. Donley.; Ryan M. Hernandez.; Chet Carter.; Michael D. Carducci.; Alice Dawson.; David F. O'Brien.; Neal R. Armstrong. Octakis(2-benzyloxyethylsulfanyl) Copper (II) Phthalocyanine: A New Liquid Crystalline Discotic Material with Benzyl-Terminated, Thioether-Linked Side Chains. Chem. Mater.2005,17 (7),1618-1627. DOI:10.1021/CM0483745
Org. Lett. 5, 4049-4052, (2003) 2. Chem. Mater. 17, 1618, (2005)
Benzyl 2-bromoethyl ether Preparation Products And Raw materials
Raw materials
Preparation Products
Benzyl 2-bromoethyl ether Suppliers
- Tel
- --
- Fax
- --
- fo@acros.com
- Country
- Belgium
- ProdList
- 3824
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@acros.com
- Country
- Belgium
- ProdList
- 6772
- Advantage
- 81
View Lastest Price from Benzyl 2-bromoethyl ether manufacturers
- Product
- BENZYL 2-BROMOETHYL ETHER 1462-37-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-04
- Product
- 2-Benzyloxy-1-bromoethane 1462-37-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-30
- Product
- Benzyl 2-bromoethyl ether 1462-37-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 100tons
- Release date
- 2023-09-12