ChemicalBook > CAS DataBase List > AC-IETD-AFC
AC-IETD-AFC
- Product Name
- AC-IETD-AFC
- CAS No.
- 211990-57-7
- Chemical Name
- AC-IETD-AFC
- Synonyms
- AC-IETD-AFC;AC-ILE-GLU-THR-ASP-AFC;Caspase 8 Substrate 1f;CGUOWXRXLQXOKO-FCQBACSVSA-N;M.W. 729.66 C31H38F3N5O12;CASPASE-8 FLUOROGENIC SUBSTRATE;CASPASE 8 SUBSTRATE 1F, FLUOROGENIC;GRANZYME B SUBSTRATE I, COLORIMETRIC;AC-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;N-ACETYL-ILE-GLU-THR-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN)
- CBNumber
- CB1395556
- Molecular Formula
- C31H38F3N5O12
- Formula Weight
- 729.65
- MOL File
- 211990-57-7.mol
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AC-IETD-AFC Property
- Boiling point:
- 1113.8±65.0 °C(Predicted)
- Density
- 1.437±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO
- pka
- 4.09±0.10(Predicted)
- form
- Lyophilized powder
- color
- White to off-white
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N-Bromosuccinimide Price
Alfa Aesar
- Product number
- J64258
- Product name
- N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin
- Packaging
- 5mg
- Price
- $161
- Updated
- 2021/12/16
Cayman Chemical
- Product number
- 17480
- Product name
- Ac-IETD-AFC
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17480
- Product name
- Ac-IETD-AFC
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $193
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17480
- Product name
- Ac-IETD-AFC
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $321
- Updated
- 2024/03/01
TRC
- Product number
- A795613
- Product name
- Ac-IETD-AFC
- Packaging
- 5mg
- Price
- $145
- Updated
- 2021/12/16
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AC-IETD-AFC Chemical Properties,Usage,Production
Uses
N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin is a fluorogenic substrate for caspases -6, -8, and -10. The IETD sequence is based on the procaspase-3 cleavage site. Residues 172-175 of procaspase-3 are cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3.
Uses
Ac-IETD-AFC is a fluorogenic substrate for caspase-8/caspase-3 processing enzyme and granzyme B. It is also a substrate for caspase-10. The IETD sequence is based on caspase-3 proenzyme cleavage site.
AC-IETD-AFC Preparation Products And Raw materials
Raw materials
Preparation Products
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AC-IETD-AFC Suppliers
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15839
- Advantage
- 69
- Tel
- 21-61263452 13641803416
- Fax
- 86-21-61263399
- ymbetter@glbiochem.com
- Country
- China
- ProdList
- 9981
- Advantage
- 64
- Tel
- 010-82967028 13552068683
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12438
- Advantage
- 60
- Tel
- 0330-2528181
- Fax
- 0330-2528171
- sales@vdmbio.com
- Country
- United States
- ProdList
- 510
- Advantage
- 64
- Tel
- 021-20242659 18930833303
- Fax
- +86 (21) 2024-2659
- Sales@changyanchem.cn
- Country
- China
- ProdList
- 5010
- Advantage
- 55
- Tel
- 010-50973186 4009686088
- 3193328036@qq.com
- Country
- China
- ProdList
- 18338
- Advantage
- 68
- Tel
- 17705183659
- Fax
- 84523390
- sales@njleonbiotech.com
- Country
- China
- ProdList
- 5501
- Advantage
- 55
- Tel
- 025-025-58361106-805-805 13082558573
- Fax
- 025-58361106-806
- liugang@njpeptide.com
- Country
- China
- ProdList
- 9979
- Advantage
- 55
- Tel
- 0571-87213919
- Fax
- 0571-87213919
- Eric@peptidego.com
- Country
- China
- ProdList
- 6756
- Advantage
- 58
- Tel
- meitaochem@126.com
- meitaochem@126.com
- Country
- China
- ProdList
- 19103
- Advantage
- 58
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View Lastest Price from AC-IETD-AFC manufacturers
Career Henan Chemical Co
- Product
- AC-IETD-AFC 211990-57-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-03-05